Splenic histology and histopathology: An update

Seminars in Diagnostic Pathology

Volumn 20, Issue 2, 2003, Pages 84-93

  Kraus, Madeleine D ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Hypersplenism; Littoral; Red pulp; Spleen; Splenectomy; Splenomegaly; White pulp

Indexed keywords

AUTOPSY; CLINICAL FEATURE; ERYTHROPHAGOCYTOSIS; HISTOLOGY; HISTOPATHOLOGY; HUMAN; HYPERSPLENISM; IMMUNE STATUS; IMMUNOLOGY; METHODOLOGY; MORPHOMETRICS; ORGANOGENESIS; PATHOLOGY; PRIORITY JOURNAL; REVIEW; SPLEEN; SPLEEN DISEASE; SPLEEN INJURY; SPLENOMEGALY; THROMBOCYTOPENIA; TISSUE FIXATION;

EID: 0042029678     PISSN: 07402570     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0740-2570(03)00024-8     Document Type: Article

References (66)

1. Timens W, Rozenboom-Uiterwijk T, Poppema S: Fetal and neonatal development of the human spleen: An immunohistochemical study. Immunology 60:603-609, 1987
2. Roberts CW, Shutter JR, Korsmeyer SJ: Hox11 controls the genesis of the spleen. Nature 368:747-749, 1994
3. Dear TN, Colledge WH, Carlton MB, et al: The Hox11 gene is essential for cell survival during spleen development. Development 121:2909-2915, 1995
4. Roberts CW, Sonder AM, Lumsden A, et al: Developmental expression of HOX11 and specification of splenic cell fate. Am J Pathol 146:1089-1101, 1995
5. Lu J, Chang P, Richardson JA, et al: The basic helix-loop-helix transcription factor capsulin controls spleen organogenesis. Proc Nat Acad Sci 97:9525-9530, 2000
6. Patterson M: A mean spleen gene. [Comment] Nat Rev Genet 1:8, 2000
7. Van Krieken JHJM, Feller AC, te Velde J: The distribution of non-Hodgkin's lymphoma in the lymphoid compartments of the human spleen. Am J Surg Pathol 13:757-765, 1989
8. Van Krieken JHJM, te Velde: Normal histology of the spleen, in Sternberg S (ed.): Histology for Pathologists. New York, NY, Raven Press, 1991, pp 253-260
9. Steininger B, Barth P, Herbst B, et al: The species-specific structure of microanatomical compartments in the human spleen. Immunology 92:307-316, 1997
10. Edelman M, Evans L, Zee S, et al: Splenic micro-anatomical localization of small lymphocytic lymphoma/chronic lymphocytic leukemia using a novel combined silver nitrate and immunoperoxidase technique. Am J Surg Pathol 21:445-452, 1997
11. Van Krieken JHJM, te Velde J: Immunohistology of the human spleen: Inventory of the localization of lymphocyte subpopulations. Histopathology 10:285-294, 1986
12. Arber DA, Strickler JG, Chen YY, et al: Splenic vascular tumors: An histologic, immunophenotypic, and virologic study. Am J Surg Pathol 21:827-835, 1997
13. Rosso R, Gianelli U, Chan JKC: Further evidence supporting the sinus lining cell nature of splenic littoral cell angiosarcoma [letter]. Am J Surg Pathol 20:1531, 1996
14. Zukerberg LR, Kaynor BL, Silverman ML, et al: Splenic hamartoma and capillary hemangioma are distinct entities: Immunohistochemical evaluation of CD8 expression by endothelial cells. Hum Pathol 22:1258-1261, 1991
15. Pinkus GS Warhol MJ, O'Connor EM, et al: Immunohistochemical localization of smooth muscle myosin in human spleen, lymph nodes and other lymphoid tissue: Unique staining pattern in white pulp and sinuses, lymphoid follicles and certain vasculature, with ultrastructural correlations. Am J Pathol 1223:440-453, 1986
16. Toccanier-Pelte MF, Skalli O, Kamanci Y, et al: Characterization of splenic stromal cells with myoid features in normal and pathologic conditions. Am J Pathol 129:109-118, 1987
17. Wilkins BS, Jones DB, Treasure JM, Delsol G: Alpha smooth muscle actin expression and white pulp compartmentalization in normal and reactive spleen. J Anatomy 187:206, 1995
18. Steiniger B, Barth P, Hellinger A: The perifollicular and marginal zones of the splenic white pulp: Do fibroblasts guide lymphocyte immigration? Am J Pathol 159:501-512, 2001
19. Bourdessoule D, Gaulard P, Mason DY: Preferential localization of human lymphocytes bearing γ/δ T cell receptors to the red pulp of the spleen. J Clin Pathol 43:461-464, 1990
20. Satoh T, Takeda R, Oikawa H, et al: Immunohistochemical and structural characteristic of the reticular framework of the white pulp and marginal zone in the human spleen. Anatom Rec 249:486-494, 1997
21. Spencer J, Perry ME, Dunn-Walters DK: Human marginal. zone B cells. Immunol Today 19:421-426, 1998
22. Kraus MD, Fleming MD, Vonderheide RH: The diagnostic splenectomy: 10 years' experience at two tertiary care institutions. Cancer 91:2001-2009, 2001
23. Kraus MD, Bartlett NL, Fleming MD, et al: Splenic pathology in myelo-dysplasia: A report of 13 cases with clinical correlation. Am J Surg Pathol 22:1255-1266, 1998
24. Cronin CC, Brady MP, Murphy C, et al: Splenectomy in patients with undiagnosed splenomegaly. Postgrad Med J 70:288-329, 1994
25. Delsol G, Diebold J, Isaacson PG, et al: Pathology of the spleen: Report on the Workshop of the VIIIth meeting of the European Association for Hematopathology. Histopathology 32:172-179, 1988
26. Letoquart J-P, La Gamma A, Kunin N, et al: Splenectomy for splenomegaly exceeding 1000 gm: Analysis of 47 patients. Br J Surg 80:334-335, 1993
27. Pawade J, Wilkins BS, Wright DH: Low-grade B-cell lymphomas of the splenic marginal zone: A clinicopathological and immunohistochemical study of 14 cases. Histopathology 27:129-137, 1995
28. Pittaluga S, Verhoef G, Criel A, et al: "Small" B-cell non-Hodgkin's lymphomas with splenomegaly at presentation are either mantle cell lymphoma or marginal zone cell lymphoma. Am J Surg Pathol 20:211-223, 1996
29. Palutke M, Eisenberg L, Narang S, et al: B lymphocytic lymphoma (large cell) of possible splenic marginal zone origin presenting with prominent splenomegaly and unusual red pulp distribution. Cancer 62:593-600, 1988
30. Cummings OW, Mazur MT: Breast cancer diffusely metastatic to the spleen: Two cases presenting as idiopathic thrombocytopenic purpura. Am J Clin Pathol 97:484-489, 1992
31. Burke JS: Surgical pathology of the spleen: an approach to differential diagnosis of splenic lymphomas and leukemias. Part II: Diseases of Red Pulp. Am J Surg Pathol 5:681-694, 1981
32. Burke JS: Splenic lymphoid hyperplasia versus lymphoma/leukemia: A diagnostic guide. Am J Clin Pathol 99:486-449, 1993
33. Farhi DC, Ashfaq R: Splenic pathology after traumatic injury. Am J Clin Pathol 105:474-478, 1996
34. Drachenberg CB, Papadimitriou JC: Splenic pathology in different forms of traumatic injury [letter]. Am J Clin Pathol 106:695, 1996
35. Ost A, Nilsson-Ardnor S, Henter JI: Autopsy findings in 27 children with hemophagocytic lymphohistiocytosis. Histopathology 32:310-316, 1998
36. Gaffey MJ, Frierson HF Jr, Medeiros LJ, et al: The relationship of Epstein-Barr virus to infection-related (sporadic) and familial hemophagocytic syndrome and secondary hemophagocytosis: An in situ hybridization study. Hum Pathol 24:657-667, 1993
37. Marti M, Feliu E, Campo E, et al: Comparative study of spleen pathology in drug abusers with thrombocytopenia related to human immunodeficiency virus infection and in patients with idiopathic thrombocytopenic purpura. Am J Clin Pathol 100:633-642, 1993
38. Jaffe ES, Costa J, Fauci AS, et al: Malignant lymphoma and erythrophagocytosis simulating malignant histiocytosis. Am J Med 75:741-749, 1983
39. Mori N, Yamashita Y, Tsuzuki T, et al: Lymphomatous features of aggressive NK cell leukaemia/lymphoma with massive necrosis, haemophagocytosis and EB virus infection. Histopathology 37:363-371, 2000
40. Parizshakaya M, Reyes J, Jaffe R: Hemophagocytic syndrome presenting as acute hepatic failure in two infants: Clinical overlap with neonatal hemochromatosis. Pediatr Dev Pathol 2:360-366, 1999
41. Wilkins BS, Green A, Wild AE, et al: Extramedullary haemopoiesis in fetal and adult human spleen: A quantitative immunohistological study. Histopathology 24:241-247, 1994
42. Mackie M, Shephard B: The spleen in myeloproliferative disorders, in Cuschieri A, Forbes C (eds.): Disorders of the Spleen. Oxford, Blackwell Scientific Press, 1994, pp 121-137
43. Mesa RA, Li CY, Schroeder G, et al: Clinical correlates of splenic Histopathology and splenic karyotype in myelofibrosis with myeloid metaplasia. Blood 97:3665-3667, 2001
44. Kraus MD, personal observation, October 2002
45. Beckman EN, Oehrle JS: Fibrous hematopoietic tumors arising in agnogenic myeloid metaplasia. Hum Pathol 13:804-810, 1982
46. Falkan F, Michal M: Nodular transformation of splenic red pulp due to carcinomatous infiltration: A diagnostic pitfall. Histopathology 25:175-178, 1994
47. Burke JS: Extranodal hematopoietic/lymphoid disorders. Am J Clin Pathol 111(Suppl 1):S40-45, 1999
48. Falk S, Stutte HJ: Manifestations of malignant lymphomas in the spleen: An histologic and immunohistochemical study of 500 cases. Prog Surg Pathol 12:49-95, 1992
49. Rakozy CK, Mohamed AN, Vo TD, et al: CD56+/CD4+ lymphomas and leukemias are morphologically, immunophenotypically, cytogenetically, and clinically diverse. Am J Clin Pathol 116:168-76, 2001
50. Yoe J, Gause BL, Curti BD, et al: Development of rheumatoid arthritis after treatment of large granular lymphocyte leukemia with deoxycofromaycin. Am J Hematol 57:253-257, 1998
51. Yoe J, Gause BL, Curti BD, et al: Development of rheumatoid arthritis after treatment of large granular lymphocyte leukemia with deoxycofromaycin. Am J Hematol 57:253-257, 1998
52. Lamy T, Loughran TP: Current concepts: Large granular lymphocyte leukemia. Blood Rev 13:230-240, 1999
53. Agnarsson BA, Loughran TP, Starkenbaum G, et al: The pathology of large granular lymphocyte leukemia. Hum Pathol 20:643-651, 1989
54. Nagakawa A, Masafum I, Saga S: Fatal cytotoxic T cell proliferatinin chronic active Epstein Barr virus infection in childhood. Am J Clin Pathol 117:283-290, 2002
55. Shin SS, Berry GJ, Weiss LM: Infectios monucleosis: Diagnosis by in situ hybridization in two cases with atypical features. Am J Surg Pathol 15:625-631, 1991
56. Strickler JG, Fedeli F, Horwitz CA, et al: Infectious mononucleosis in lymphoid tissue. Arch Pathol Lab Med 117:269-278, 1993
57. Satoh T, Yamada T, Nakano S, et al: The relationship between primary splenic malignant lymphoma and chronic liver disease associated with hepatitis C virus infection. Cancer 80:1981-1988, 1997
58. Agnello V, Mecucci C, Casato M: Regression of splenic lymphoma after treatment of hepatitis C virus infection. N Engl J Med 347:2168-2170, 2002
59. Timesn W, Poppema S: Lymphocyte compartments in human spleen: An immunohistological study. Am J Pathol 120:443-454, 1985
60. Burke JS: Surgical pathology of the spleen: An approach to differential diagnosis of splenic lymphomas and leukemias. Part I: Diseases of White Pulp. Am J Surg Pathol 5:551-563, 1981
61. Isaacson PG: Malignant lymphomas with a follicular growth pattern. Histopathology 28:487-495, 1996
62. Izumi M, Mochizuki M, Kuroda M, et al: Angiomyoid proliferative lesion: an unusual stroma-rich variant of Castleman's disease of hyaline-vascular type. Virchows Archiv 441:400-405, 2002
63. Ordi J, Grau JM, Junque A, et al: Secondary (AA) amyloidosis associated with Castleman's disease: Report of 2 cases and a review of the literature. Am J Clin Pathol 100:394-397, 1993
64. Alkan S, Ross CR, Hanson CA, et al: Follicular lymphoma with involvement of the splenic marginal zone: A pitfall in the differential diagnosis of splenic marginal zone lymphoma. Hum Pathol 27:503-506, 1996
65. Schmid U, Cogliatti SB, Diss TC, et al: Monocytoid/marginal zone B cell differentiation in follicle center cell lymphoma. Histopathology 29:201-208, 1996
66. Kurtin PJ: Marginal zone B cells, monocytoid B cells, and the follicular microenvironment: Determinants of morphologic features in a subset of low-grade B-cell lymphomas. Am J Clin Pathol 114:505-508, 2000