Bizarre leiomyomas of the uterus: A comprehensive pathologic study of 24 cases with long-term follow-up

American Journal of Surgical Pathology

Volumn 21, Issue 11, 1997, Pages 1261-1270

  Downes, Katharine A ^a   Hart, William R ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Atypical; Bizarre leiomyoma; Leiomyoma; Smooth muscle tumor; Symplastic; Uterus

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYSTERECTOMY; LEIOMYOMA; MITOSIS; MUSCLE TUMOR; TUMOR CELL; UTERUS MYOMA; UTERUS TUMOR;

ADULT; FEMALE; FOLLOW-UP STUDIES; HUMANS; LEIOMYOMA; MIDDLE AGED; MITOTIC INDEX; SURVIVAL RATE; UTERINE NEOPLASMS;

EID: 0030831544     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199711000-00001     Document Type: Article

References (29)

1. Amada S, Nakano H, Tsuneyoshi M. Leiomyosarcoma versus bizarre and cellular leiomyomas of the uterus: a comparative study based on the MIB-1 and proliferating cell nuclear antigen indices, p53 expression, DNA flow cytometry, and muscle specific actin. Int J Gynecol Pathol 1995;14:134-42.
2. Bell SW, Kempson RL, Hendrickson MR. Problematic uterine smooth muscle neoplasms: a clinicopathologic study of 213 cases. Am J Surg Pathol 1994;18:535-58.
3. Burns B, Curry RH, Bell MEA. Morphologic features of prognostic significance in uterine smooth muscle tumors: a review of eighty-four cases. Am J Obstet Gynecol 1979;135:109-14.
4. Christopherson WM, Williamson EO, Gray LA. Leiomyosarcoma of the uterus. Cancer 1972;29:1512-7.
5. Evans HL, Chawla SP, Simpson C, et al. Smooth muscle neoplasms of the uterus other than ordinary leiomyoma. A study of 46 cases, with emphasis on diagnostic criteria and prognostic factors. Cancer 1988;62:2239-17.
6. Fechner RE. Atypical leiomyomas and synthetic progestin therapy. Am J Clin Pathol 1968;49:697-703.
7. Hart WR. Problematic uterine smooth muscle neoplasms [Letter]. Am J Surg Pathol 1997;21:252.
8. Hart WR. Unpublished observations.
9. Hart WR, Billman JK. A reassessment of uterine neoplasms originally diagnosed as leiomyosarcomas. Cancer 1978;41:1902-10.
10. Hendrickson MR, Kempson RL. The uterine corpus. In: Sternberg SS, ed. Diagnostic Surgical Pathology. 2nd ed. New York: Raven Press, 1994:2091.
11. Kelly HA, Cullen TS. Myomata of the Uterus. Philadelphia: WB Saunders, 1909.
12. Kempson RL, Bari W. Uterine sarcomas: classification, diagnosis and prognosis. Hum Pathol 1970;1:331-49.
13. Kempson RL, Hendrickson MR. Pure mesenchymal neoplasms of the uterine corpus: selected problems. Semin Diagn Pathol 1988; 5:172-98.
14. Mazur MT, Kraus FF. Histogenesis of morphologic variations in tumors of the uterine wall. Am J Surg Pathol 1980;4:59-74.
15. Myles JL, Hart WR. Apoplectic leiomyomas of the uterus: a clinicopathologic study of five distinctive hemorrhagic leiomyomas associated with oral contraceptive usage. Am J Surg Pathol 1985; 9:798-805.
16. Novak E, Anderson DF. Sarcoma of the uterus. Clinical and pathologic study of fifty-nine cases. Am J Obstet Gynecol 1937;34:740-60.
17. Oliva E, Young RH, Clement PB, Bhan AK, Scully RE. Cellular benign mesenchymal tumors of the uterus: a comparative morphologic and immunohistochemical analysis of 33 highly cellular leiomyomas and six endoimetrial stromal nodules, two frequently confused tumors. Am J Surg Pathol 1995;19:757-68.
18. Ozisik YY, Meloni AM, Sandberg AA, Surti U, Tobon H, Davare J. Cytogenetic findings in a symplastic leiomyoma [Letter]. Cancer Genet Cytogenet 1993;67:79-80.
19. Perrone T, Dehner LP. Prognostically favorable "mitotically active" smooth-muscle tumors of the uterus: a clinicopathologic study of ten cases. Am J Surg Pathol 1988;12:1-8.
20. Phillipe E, Borrel D. Leiomyomes pseudosarcomateux de l'uterus: myomes a cellules fusiformes, myomes plexiformes et myomes avec anomalies nucleaires. J Gynecol Obstet Biol Reprod 1975;4: 657-70.
21. Prakash S, Scully RE. Sarcoma-like pseudopregnancy changes in uterine leiomyomas: report of a case resulting from prolonged norethindrone therapy. Obstet Gynecol 1964;24:106-10.
22. Prayson RA, Goldhlum JR, Hart WR. Epithelioid smooth muscle tumors of the uterus: a clinicopalhologic study of 18 patients. Am J Surg Pathol 1997;21:383-91.
23. Prayson RA, Hart WR. Mitotically active leiomyomas of the uterus. Am J Clin Pathol 1992;97:14-20.
24. Prayson RA, Hart WR. Pathologic considerations of uterine smooth muscle tumors. Obstet Gynecol Clin North Am 1995;22: 637-57.
25. Przybora LA. Leiomyosarcoma in situ of the uterus. Cancer 1961; 14:483-92.
26. Scully RE, Bonfiglio TA, Kurman RJ, Silverberg SG, Wilkinson EJ. Histological typing of female genital tract tumours. World Health Organization International Histological Classification of Tumours. 2nd ed. Berlin: Springer-Verlag, 1994.
27. Silverberg SG, Kurman RJ. Tumors of the Uterine Corpus and Gestational Trophoblaatic Disease. Atlas of Tumor Pathology. Third Series, Fascicle 3. Washington, DC: Armed Forces Institute of Pathology, 1991:127.
28. Sreenan JJ, Prayson RA, Biscotti CV, Thornton MH, Easley KA, Hart WR. Hislopathologic findings in 107 uterine leiomyomas treated with leuprolide acetate compared with 126 controls. Am J Surg Pathol 1996;20:427-32.
29. Taylor HB, Norris HJ. Mesenchymal tumors of the uterus: IV. Diagnosis and prognosis of leiomyosarcomas. Arch Pathol 1966; 82:40-4.