Droplet-based magnetically activated cell separation

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

Volumn 26 IV, Issue , 2004, Pages 2575-2578

  Kim, Y H ^a   Hong, S ^b   Kim, B ^a   Yun, S ^a   Kang, Y R ^a   Paek, K K ^c   Lee, J W ^a   Lee, S H ^b   Ju, B K ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Korea University   (South Korea)

^c Daejin University   (South Korea)

Author keywords

Cell separation; Droplet; MACS; Magnet

Indexed keywords

CELLS; CYTOLOGY; GRAVITATION; MAGNETIC RESONANCE IMAGING; SATURATION (MATERIALS COMPOSITION); SCHEMATIC DIAGRAMS; SURFACE TENSION; TURBULENCE;

CELL SEPARATION; DROPLET; FLUORESCENT ACTIVATED CELL SORTING (FACS); MACS;

SEPARATION;

EID: 11144332124     PISSN: 05891019     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (25)

1. A. K. Gupta and S. Wells, "Surface-Modified Supeiparamagnetic Nanoparticles for Drug Delivery: Preparation, Characterization, and Cytotoxicity Studies," IEEE Transactions on Nanobioscience, vol. 3, no. 1, pp. 66-73, March 2004.
2. C. Chouly, D. Pouliquen, L. Lucet, J. J. Jeune, and P. Jallet, "Development of superparamagnetic nanoparticles for MRI: Effect of particle size, charge and surface nature on biodistribution," J. Microencapsulation, vol. 13, pp. 245-255, 1996.
3. P. K. Gupta and C. T. Hung, "Magnetically controlled targeted microcarrier systems," Life Sci., vol. 44, pp. 175-186, 1989.
4. M. Berger, J. Castelino, R. Huang, M. Shah, and R. H. Austin, "Design of a microfabricated magnetic cell separator," Electrophoresis, vol. 22, pp. 3883-3892, 2001.
5. K. E. McCloskey, L. R. Moore, M. Hoyos, A. Rodriguez, J. J. Chalmers, and M. Zborowski, "Magnetophoretic Cell Sorting Is a Function of Antibody Binding Capacity," Biotechnol. Prog., vol. 19, pp. 899-907, 2003.
6. K. E. McCloskey, K. Comella, J. J. Chalmers, S. Margel, and M. Zborowski, "Mobililty Measurements of Immunomagnetically Labeled Cells Allow Quantitation of Secondary Antibody Binding Amplification," Biotechnology and Bioengineering, vol. 75, no. 6, pp. 642-655, 2001.
7. B. G. Hosu, K. Jakab, P. Banki, F. I. Toth, and G. Forgacs, "Magnetic Tweezers for intracellular applications," Review of Scientific Instruments, vol. 74, no. 9, pp. 4158-4163, 2003.
8. F. J. Alenghat, B. Fabry, K. Y. Tsai, W. H. Goldmann, and D. E. Ingber, "Analysis of Cell Mechanics in Single Vinculin-Deficient Cells Using a Magnetic Tweezer," Biochemical and Biophysical Research Communications, vol. 277, no. 1, pp. 93-99, 2000.
9. A. R. Bausch, F. Ziemann, A. A. Boulbitch, K. Jacobson, and E. Sackmann, "Local Measurements of Viscoelastic Parameters of Adherent Cell Surfaces by Magnetic Bead Microrheometry," Biophysical Journal, vol. 75, pp. 2038-2049, 1998.
10. T. Deng, G. M. Whitesides, M. Radhakrishnan, G. Zabow, and M. Prentiss, "Manipulation of magnetic microbeads in suspension using micromagnetic systems fabricated with soft lithography," Applied Physics Letters, vol. 78, no. 12, pp. 1775-1777, MARCH 19, 2001.
11. S. Miltenyi, "Methods And Materials For Improved High Gradient Magnetic Separation Of Biological Materials," U.S. Patent 5 411 863, 1995.
12. P. Landsorp and T. Thomas, "Device for Separating Magnetically Labelled Cells," U.S. Patent 5 514 340, 1996.
13. T. Deng, M. Prentiss, and G. M. Whitesides, "Fabrication of magnetic microfiltration systems using soft lithography," Applied physics letters, vol. 80, no. 3, pp. 461-463, January 21, 2002.
14. G. Zabow, F. Assi, R. Jenks, and M. Prentiss, "Guide microfluidics by electromagnetic capillary focusing," Applied physics letters, vol. 80, no. 8, pp. 1483-1485, 2002.
15. F. Assi and R. Jenks, "Massively parallel adhesion and reactivity measurements using simple and inexpensive magnetic tweezers," Journal of applied physics, vol. 92, no. 9, pp. 5584-5586, 2002.
16. th IEEE International Conference on Micro Electro Mechanical Systems, pp. 530-533, 2003.
17. C. A. Lepre and J. M. Moore, "Microdrop screening: A rapid method to optimize solvent conditions for NMR spectroscopy of proteins," Journal of Biomolecular NMR, pp. 493-499, 1998.
18. F. Schonfeld and D. Rensink, "Simulation of Droplet Generation by Mixing Nozzles," Chem. Eng. Technol., vol. 26, pp. 585-591, 2003.
19. V. I. Terekhov, M. A. Pakhomov, and V. V. Chichindaev, "Effect of Evaporation of Liquid Droplets on the Distribution of Parameters in a Two-Species Laminar Flow," Journal of Applied Mechanics and Technical Physics, vol. 41, no. 6, pp. 1020-1028, 2000.
20. J. A. Schwartz, J. V. Vykoukal, and P. R. C. Gascoyne, "Droplet-based chemistry on a programmable micro-chip," Lab on a Chip, vol. 4, pp. 11-17, 2004.
21. th IEEE International Conference on Micro Electro Mechanical Systems, pp. 335-338, 2003.
22. S. K. Cho, H. J. Moon, and C.-J. Kim, "Creating, Transporting, Cutting, and Merging Liquid Droplets by Electrowetting-Based Actuation for Digital Microfluidic Circuits," Journal of Microelectromechanical Systems, vol. 12, no. 1, pp. 70-80, 2003.
23. th IEEE International Conference on Micro Electro Mechanical Systems, pp. 359-362, January 25-29, 2004
24. Flow Cytometry, Available: http://www.dakocytomation.com/index/ about_whatwedo/about_business_flow.htm
25. Cell Quest Software User's Guide, BECTON DICKINSON, San Jose, CA, 1994.