Enhanced immunoglobulin A response and protection against Salmonella enterica serovar Typhimurium in the absence of the substance P receptor

Infection and Immunity

Volumn 73, Issue 1, 2005, Pages 317-324

  Walters, Nancy ^a   Trunkle, Theresa ^a   Sura, Michael ^a   Pascual, David W ^a  

^a MONTANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN; CD4 ANTIGEN; COLONIZATION FACTOR ANTIGEN I; IMMUNOGLOBULIN A; INTERLEUKIN 10; NEUROKININ 1 RECEPTOR; SALMONELLOSIS VACCINE; SUBSTANCE P; SUBSTANCE P RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ESCHERICHIA COLI; EXPRESSION VECTOR; FEMALE; FIMBRIA; HELPER CELL; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; INFLAMMATION; KNOCKOUT MOUSE; LAMINA PROPRIA; MALE; MOUSE; MUCOSA; NONHUMAN; ORGAN WEIGHT; PERITONEUM MACROPHAGE; PEYER PATCH; PRIORITY JOURNAL; PROVOCATION TEST; SALMONELLA ENTERICA; SALMONELLOSIS; SEROTYPE; SPLEEN; SURVIVAL RATE;

ANIMALS; ANTIBODIES, BACTERIAL; FIMBRIAE PROTEINS; IMMUNIZATION; IMMUNOGLOBULIN A; INTERLEUKIN-10; INTERLEUKIN-5; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; RECEPTORS, NEUROKININ-1; SALMONELLA TYPHIMURIUM;

EID: 11144314769     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.1.317-324.2005     Document Type: Article

References (47)

1. Ascón, M. A., D. M. Hone, N. Walters, and D. W. Pascual. 1998. Oral immunization with a Salmonella vaccine vector expressing recombinant enterotoxigenic Escherichia coli K99 fimbriae elicits elevated antibody titers for protective immunity. Infect. Immun. 66:5470-5476.
2. Beagley, K. W., J. H. Eldridge, H. Kiyono, M. P. Everson, W. J. Koopman, T. Honjo, and J. R. McGhee. 1988. Recombinant murine IL-5 induces high rate IgA synthesis in cycling IgA-positive Peyer's patch B cells. J. Immunol. 141:2035-2042.
3. Beagley, K. W., J. H. Eldridge, F. Lee, H. Kiyono, M. P. Everson, W. J. Koopman, T. Hirano, T. Kishimoto, and J. R. McGhee. 1989. Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells. J. Exp. Med. 169:2133-2148.
4. Bost, K. L., and J. D. Clements. 1997. Intracellular Salmonella dublin induces substantial secretion of the 40-kilodalton subunit of interleukin-12 (IL-12) but minimal secretion of IL-12 as a 70-kilodalton protein in murine macrophages. Infect. Immun. 65:3186-3192.
5. Bozic, C. R., B. Lu, U. E. Hopken, C. Gerard, and N. P. Gerard. 1996. Neurogenic amplification of immune complex inflammation. Science 273: 1722-1725.
6. Braun, A., P. Wiebe, A. Pfeufer, R. Gessner, and H. Renz. 1999. Differential modulation of human immunoglobulin isotype production by the neuropeptides substance P, NKA, and NKB. J. Neuroimmunol. 97:43-50.
7. Bullifent, H. L., K. F. Griffin, S. M. Jones, A. Yates, L. Harrington, and R. W. Titball. 2000. Antibody responses to Yersinia pestis F1-antigen expressed in Salmonella typhimurium aroA from in vivo-inducible promoters. Vaccine 18:2668-2676.
8. Csencsitis, K. L., and D. W. Pascual. 2002. Absence of L-selectin delays mucosal B cell responses in nonintestinal effector tissues. J. Immunol. 169: 5649-5659.
9. Curtiss, R., S. M. Kelly, P. A. Gulig, and K. Nakayama. 1989. Selective delivery of antigens by recombinant bacteria. Curr. Top. Microbiol. Immunol. 146:34-49.
10. Curtiss, R., S. M. Kelly, and J. O. Hassan. 1993. Live oral avirulent Salmonella vaccines. Vet. Microbiol. 37:397-405.
11. Dybing, J. K., N. Walters, and D. W. Pascual. 1999. The role of endogenous IL-18 in resolving wild-type and attenuated Salmonella typhimurium infections. Infect. Immun. 67:6242-6248.
12. Elsawa, S. F., W. Taylor, C. C. Petty, I. Marriott, J. V. Weinstock, and K. L. Best. 2003. Reduced CTL response and increased viral burden in substance P receptor-deficient mice infected with murine γ-herpesvirus 68. J. Immunol. 170:2605-2612.
13. Fennelly, G. J., S. A. Khan, M. A. Abadi, T. F. Wild, and B. R. Bloom. 1999. Mucosal DNA vaccine immunization against measles with a highly attenuated Shigella flexneri vector. J. Immunol. 162:1603-1610.
14. Girón, J. A., J.-G. Xu, C. R. González, D. Hone, J. B. Kaper, and M. M. Levine. 1995. Simultaneous expression of CFA/I and CS3 colonization factor antigens of enterotoxigenic Escherichia coli by ΔaroC, ΔaroD Salmonella typhi vaccine strain CVD 908. Vaccine 13:939-946.
15. Hall, R. H., D. R. Maneval, Jr., J. H. Collins, J. L. Theibert, and M. M. Levine. 1989. Purification and analysis of colonization factor antigen 1, coli surface antigen 1, and coli surface antigen 3 fimbriae from enterotoxigenic Escherichia coli. J. Bacteriol. 171:6372-6374.
16. Hokfelt, T., B. Pernow, and J. Wahren. 2001. Substance P: a pioneer amongst neuropeptides. J. Intern. Med. 249:27-40.
17. Ichikawa, S., S. P. Sreedharan, E. J. Goetzl, and R. L. Owen. 1994. Immunohistochemical localization of peptidergic nerve fibers and neuropeptide receptors in Peyer's patches of the cat ileum. Regul. Pept. 54:385-395.
18. Joos, G. F., K. O. De Swert, and R. A. Pauwels. 2001. Airway inflammation and tachykinins: prospects for the development of tachykinin receptor antagonists. Eur. J. Pharmacol. 429:239-250.
19. Kang, H. Y., J. Srinivasan, and R. Curtiss III. 2002. Attenuated Salmonella enterica serovar Typhi expressing urease effectively immunizes mice against Helicobacter pylori challenge as part of a heterologous mucosal priming-parenteral boosting vaccination regimen. Infect. Immun. 70:5096-5106.
20. Kidd, B. L., J. J. Inglis, K. Vetsika, V. C. Hood, C. De Felipe, H. Bester, S. P. Hunt, and S. C. Cruwys. 2003. Inhibition of inflammation and hyperalgesia in NK-1 receptor knock-out mice. Neuroreport 14:2189-2192.
21. Kincy-Cain, T., and K. L. Best. 1996. Increased susceptibility of mice to Salmonella infection following in vivo treatment with the substance P antagonist, spantide II. J. Immunol. 157:255-264.
22. Kincy-Cain, T., and K. L. Best. 1997, Substance P-induced IL-12 production by murine macrophages. J. Immunol. 158:2334-2339.
23. Kulkarni-Narla, A., A. J. Beitz, and D. R. Brown. 1999. Catecholaminergic, cholinergic and peptidergic innervation of gut-associated lymphoid tissue in porcine jejunum and ileum. Cell Tissue Res. 298:275-286.
24. Lai, J. P., S. D. Douglas, and W. Z. Ho. 1998. Human lymphocytes express substance P and its receptor. J. Neuroimmunol. 86:80-86.
25. Lotz, M., J. H. Vaughan, and D. A. Carson. 1988. Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science 241: 1218-1221.
26. Mantyh, C. R., T. S. Gates, R. P. Zimmerman, M. L. Welton, E. P. Passaro, Jr., S. R. Vigna, J. E. Maggio, L. Kruger, and P. W. Mantyh. 1988. Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease. Proc. Natl. Acad. Sci. USA 85:3235-3239.
27. - Salmonella vaccines. Microb. Pathog. 13:477-491.
28. Mastroeni, P., B. Villareal-Ramos, J. A. Harrison, R. Demarco de Hormaeche, and C. E. Hormaeche. 1994. Toxicity of lipopolysaccharide and of soluble extracts of Salmonella typhimurium in mice immunized with a live attenuated aroA salmonella vaccine. Infect. Immun. 62:2285-2288.
29. Morrow, C. D., M. J. Novak, D. C. Ansardi, D. C. Porter, and Z. Moldoveanu. 1999. Recombinant viruses as vectors for mucosal immunity. Curr. Top. Microbiol. Immunol. 236:255-273.
30. Noriega, F. R., G. Losonsky, J. Y. Wang, S. B. Formal, and M. M. Levine. 1996. Further characterization of ΔaroA ΔvirG Shigella flexneri 2a strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector vaccine for delivering antigens of enterotoxigenic Escherichia coli. Infect. Immun. 64: 23-27.
31. + Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses. Infect. Immun. 64:1516-1525.
32. Pascual, D. W., J. Xu-Amano, H. Kiyono, J. R. McGhee, and K. L. Bost. 1991. Substance P acts directly upon cloned B lymphoma cells to enhance IgA and IgM production. J. Immunol. 146:2130-2136.
33. Pascual, D. W., K. W. Beagley, H. Kiyono, and J. R. McGhee. 1995. Substance P promotes Peyer's patch and splenic B cell differentiation, p. 52-59. In J. Mestecky et al. (ed.), Advances in mucosal immunology. Plenum Press, New York, N. Y.
34. Pascual, D. W., D. M. Hone, S. Hall, F. W. van Ginkel, M. Yamamoto, N. Walters, K. Fujihashi, R. Powell, S. Wu, J. L. Vancott, H. Kiyono, and J. R. McGhee. 1999. Expression of recombinant enterotoxigenic colonization factor antigen I by Salmonella typhimurium elicits a biphasic T helper cell response. Infect. Immun. 67:6249-6256.
35. Pascual, D. W., M. D. White, T. Larson, and N. Walters. 2001. Impaired mucosal immunity in L-selectin-deficient mice orally immunized with a Salmonella vaccine vector. J. Immunol. 167:407-415.
36. Pascual, D. W., T. Trunkle, and J. Sura. 2002. Fimbriated Salmonella enterica serovar Typhimurium abates the initial inflammatory responses by macrophages. Infect. Immun. 70:4273-4281.
37. Pascual, D. W. 2004. The role of tachykinins on bacterial infections. Front. Biosci. 9:3209-3217.
38. Payan, D. G., D. R. Brewster, and E. J. Goetzl. 1984. Stereo-specific receptors for substance P on cultured IM-9 lymphoblasts. J. Immunol. 133:3260-3265.
39. Piedimonte, G., M. M. Rodriguez, K. A. King, S. McLean, and X. Jiang. 1999. Respiratory syncytial virus upregulates expression of the substance P receptor in rat lungs. Am. J. Physiol. 277:L831-L840.
40. Ramarathinam, L., D. W. Niesel, and G. R. Klimpel. 1993. Salmonella typhimurium induces IFN-γ production in murine splenocytes: role of natural killer cells and macrophages. J. Immunol. 150:3973-3981.
41. Roberts, M., S. N. Chatfield, and G. Dougan. 1994. Salmonella as carriers of heterologous antigens, p. 27-58. In D. T. O'Hagen (ed.), Novel delivery systems for oral vaccines. CRC Press, Boca Raton, Fla.
42. Schafer, R., D. A. Portnoy, S. A. Brassell, and Y. Paterson. 1992. Induction of a cellular immune response to a foreign antigen by a recombinant Listeria monocytogenes vaccine. J. Immunol. 149:53-59.
43. Soussi, N., G. Milon, J. H. Colle, E. Mougneau, N. Glaichenhaus, and P. L. Goossens. 2000. Listeria monocytogenes as a short-lived delivery system for the induction of type 1 cell-mediated immunity against the p36/LACK antigen of Leishmania major. Infect. Immun. 68:1498-1506.
44. Stanisz, A. M., D. Befus, and J. Bienenstock. 1986. Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferation by lymphocytes from Peyer's patches, mesenteric lymph nodes, and spleen. J. Immunol. 136:152-156.
45. VanCott, J. L., H. F. Staats, D. W. Pascual, M. Roberts, S. N. Chatfield, M. Yamamoto, P. B. Carter, H. Kiyono, and J. R. McGhee. 1996. Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. J. Immunol. 156:1504-1514.
46. Weinstock, J. V., A. Blum, A. Metwali, D. Elliott, N. Bunnett, and R. Arsenescu. 2003. Substance P regulates Th1-type colitis in IL-10 knockout mice. J. Immunol. 171:3762-3767.
47. Wu, S., D. W. Pascual, J. L. VanCott, J. R. McGhee, D. R. Maneval, Jr., M. M. Levine, and D. M. Hone. 1995. Immune response to Escherichia coli and Salmonella typhimurium vectors that express colonization factor antigen I (CFA/I) of enterotoxigenic E. coli in the absence of the CFA/I positive regulator cfaR. Infect. Immun. 63:4933-4938.