Tetrahydrobiopterin augments arginine transport in rat cardiac myocytes through modulation of CAT-2 mRNA

Journal of Laboratory and Clinical Medicine

Volumn 137, Issue 5, 2001, Pages 356-362

  Schwartz, Idit F ^a   Schwartz, Doron ^a   Wollman, Yoram ^a   Chernichowski, Tamara ^a   Blum, Miriam ^a   Levo, Yoram ^a   Iaina, Adrian ^a  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIAMINO 6 HYDROXYPYRIMIDINE; AMINO ACID TRANSPORT; ARGININE; BIOPTERIN; CELL MEMBRANE TRANSPORT; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CULTURE MEDIUM; DIMERIZATION; ENZYME ACTIVITY; HEART; LIPOPOLYSACCHARIDE; MONOCYTE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; TETRAHYDROBIOPTERIN;

EID: 0035339278     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1067/mlc.2001.114338     Document Type: Article

References (42)

1. Beasley D, Schwartz JH, Brenner BM. Interleukin 1 induces prolonged L-arginine dependent cyclic guanosine mono phosphate and nitrite production in rat vascular smooth muscle cells. J Clin Invest 1991;87:602-8.
2. Granger DL, Hibbs JB Jr, Perfect JR, Durack DT. Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages. J Clin Invest 1990;85:264-73.
3. Iyengar R, Stuehr DJ, Marletta MA. Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: Precursors and role of the respiratory burst. Proc Natl Acad Sci USA 1987;84:6369-73.
4. White MF, Christensen HN. The two way flux of cationic amino acids across the plasma membrane of mammalian cells is largely explained by a single transport system. J Biol Chem 1982;257:4450-7.
5. White MF, Gazzola GC, Christensen HN. Cationic amino acid transport into cultured animal cells. 1. Influx into cultured human fibroblasts. J Biol Chem 1982;257:4443-9.
6. Albritton LM, Tseng L, Scadden D, Cunningham JM. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 1989;57:659-66.
7. Kim JW, Closs EI, Albritton LM, Cunningham JM. Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature 1991;352:725-8.
8. MacLeod CL, Finley K, Kakuda D, Kozak CA, Wilkinson MF. Activated T cells express a novel gene on chromosome 8 that is closely related to the murine ecotropic retroviral receptor. Mol Cell Biol 1990;10:3663-74.
9. Wang H, Kavanaugh MP, North RA, Kabat D. Cell surface receptor for the ecotropic murine retroviruses is a basic amino acid. Nature 1991;352:729-31.
10. Closs EI, Graf P, Habermeier A, Cunningham JM, Forsterman U. Humen cationic amino acid transporters mCAT-1, mCAT-2A, and mCAT-2B: Three related carriers with distinct transport properties. Biochemistry 1997;36:6462-8.
11. Low BC, Grigor MR. Angiotensin II stimulates system y+ and cationic amino acid transporter gene expression in cultured vascular smooth muscle cells. J Biol Chem 1995;270:27577-83.
12. Hosokawa H, Sawamura T, Kobayashi S, Ninomiya H, Miwa S, Masaki T. Cloning and characterization of a brain-specific cationic amino acid transporter. J Biol Chem 1997;272:8717-22.
13. Ito K, Groudine M. A new member of the cationic amino acid transporter family is preferentially expressed in adult mouse brain. J Biol Chem 1997;272:26780-6.
14. Simmons WW, Closs EI, Cunningham JM, Smith TW, Kelly RA. Cytokines and insulin induce cationic amino acid transporter (CAT) in cardiac myocytes. Regulation of L-arginine transport and NO production by CAT-1, CAT-2A, and CAT-2B. J Biol Chem 1996;271:11694-702.
15. Giovanelli J, Campos KL, Kaufman S. Tetrahydrobiopterin, a cofactor for rat cerebellar nitric oxide synthase, does not function as a reactant in the oxygenation of arginine. Proc Natl Acad Sci USA 1991;88:7091-5.
16. Sakai N, Kaufman S, Milstein S. Tetrahydrobiopterin is required for cytokine-induced nitric oxide production in a murine macrophage cell line (RAW 264). Mol Pharmacol 1992;43:6-10.
17. Balligand JL, Ungureanu-Longrois D, Simmons WW, Pimental D, Malinski TA, Kapturezak M, et al. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro. J Biol Chem 1994;269:27580-8.
18. Hattori Y, Gross SS. GTP cyclohydrolase 1 mRNA is induced by LPS in vascular smooth muscle. Characterization, sequence, and relationship to nitric oxide synthase. Biochem Biophys Res Commun 1993;195:435-41.
19. Scott-Burden T, ELizondo E, Ge T, Boulanger CM, Vanhoutte PM. Growth factor regulation of interleukin 1 beta induced nitric oxide synthase and GTP cyclohydrolase expression in cultured smooth muscle cells. Biochem Biophys Res Commun 1993;196:1261-6.
20. Gross SS, Levi R. Tetrahydrobiopterin synthesis. An absolute requirement for cytokine induced nitric oxide generation by vascular smooth muscle. J Biol Chem 1992;267:25722-9.
21. Mayer B, Werner ER. In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn-Schmiedebergs Arch Pharmacol 1995;351:453-63.
22. Baek KJ, Thiel BA, Lucas S, Stuehr DJ. Macrophage nitric oxide synthase subunits, purification, characterization, and role of prosthetic groups and substrate in regulating their association into a dimeric enzyme. J Biol Chem 1993;268:21120-9.
23. Griscavage JM, Fukuto JM, Komori Y, Ignarro LJ. Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide. J Biol Chem 1994;269:21644-9.
24. Green CE, Dabbs JE, Tyson CA. Functional integrity of isolated rat hepatocytes prepared by whole liver vs biopsy perfusion. Anal Biochem 1983;131:242-5.
25. Rockett KA, Awburn MM, Cowden WB, Clark JA. Killing of Plasmodium falciparum in vitro by nitric oxide derivatives. Infect Immun 1991;59:3280-3.
26. Bartholomew B. A rapid method for the assay of nitrate in the urine using the nitrate reductase enzyme of E. coli. Food Chem Toxicol 1984;22:541-3.
27. Gazzola GC, Dall' Asta V, Franchi-Gazzola R, White MF. The cluster-trey method for rapid measurement of solute fluxes in adherent cultured cells. Anal Biochem 1981;115:368-74.
28. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-9.
29. Jeffreys AJ, Wilson V, Neumann R, Keyte J. Amplification of human minisatellites by the polymerase chain reaction: Towards DNA fingerprinting of single cells. Nucleic Acids Res 1988;16:10953-71.
30. Hyatt SL, Aulak KS, Malandro M, Kilberg M, Hatzoglou S. Adaptive regulation of the cationic amino acid transporter-1 (cat-1) in Fao cells. J Biol Chem 1997;272:19951-7.
31. Stevens BR, Kakuda DK, Yu K, Waters M, Vo CB, Raizada MK. Induced nitric oxide synthesis is dependent on induced alternatively spliced CAT-2 encoding L-arginine transport in brain astrocytes. J Biol Chem 1996;271:24017-22.
32. Bredt DS, Snyder SH. Nitric oxide: A physiologic messenger molecule. Annu Rev Biochem 1994;63:175-95.
33. Gross SS, Wolin MS. Nitric oxide: Pathophysiological mechanisms. Annu Rev Physiol 1995;57:737-69.
34. Simmons WW, Ungureanu-Longrois D, Smith GK, Smith TW, Kelly RA. Glucocorticoids regulate inducible nitric oxide synthase by inhibiting tetrahydrobiopterin synthesis and L-arginine transport. J Biol Chem 1996;271:23928-37.
35. Werner ER, Werner-Felmeyer G, Fuchs D, Hausen A, Ziebnegger G, Wachter H. Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-gamma. Biochem J 1989;262:861-6.
36. Ziegler I, Schott K, Lubbert FK, Herrmann F, Schwulera U, Bacher A. Control of tetrahydrobiopterin synthesis in T lymphocytes by synergistic action of interferon gamma and interleukin-2. J Biol Chem 1990;265:17026-30.
37. Durante W, Liao L, Cheng K, Schafer AI. Selective induction of a cationic amino acid transporter by tumor necrosis factor alpha in vascular endothelium. Proc Assoc Am Physicians 1996;108:356-61.
38. Gill DJ, Low BC, Grigor MR. Interleukin-1 beta and tumor necrosis factor-alpha stimulate the cat-2 gene of the L-arginine transporter in cultured vascular smooth muscle cells. J Biol Chem 1996;271:11280-3.
39. Bogdan C, Werner E, Stenger S, Wachter H, Rollinghoff M, Felmayer GW. 2,4-Diamino-6-hydroxypyrimidine, an inhibitor of tetrahydrobiopterin synthesis, downregulates the expression of iNOS protein and mRNA in primary murine macrophages. FEBS Lett 1995;36:69-74.
40. Nicholson B, Sawamura T, Masaki T, MacLeod CL. Increased Cat3-mediated cationic amino acid transport functionally compensates in cat 1 knockout cell lines. J Biol Chem 1998;273:14663-6.
41. McDonald KK, Zharikov S, Block ER, Kilberg MS. A caveolar complex between the cationic amino acid transporter 1 and endothelial nitric oxide synthase may explain the "arginine paradox." J Biol Chem 1997;272:31213-6.
42. Schwartz D, Mendonca M, Schwartz I, Xia Y, Satriano J, Wilson CB, et al. Inhibition of constitutive nitric oxide synthase (NOS) by nitric oxide generate by inducible NOS after lipopolysaccharide administration provokes renal dysfunction in rats. J Clin Invest 1997;100:439-48.