Thrombin peptide (TP508) treatment of rat growth plate cartilage cells promotes proliferation and retention of the chondrocytic phenotype while blocking terminal endochondral differentiation

Journal of Cellular Physiology

Volumn 202, Issue 2, 2005, Pages 336-343

  Schwartz, Z ^a,b,c   Carney, D H ^d,e   Crowther, R S ^d,e   Ryaby, J T ^f   Boyan, B D ^a,b,g  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^d University of Texas Medical Branch School of Medicine   (United States)

^e Chrysalis BioTechnology Inc   (United States)

^f OrthoLogic Corporation   (United States)

^g GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; CALCITRIOL; CHRYSALIN; PEPTIDE; PROTEOGLYCAN; SULFATE; THROMBIN; THYMIDINE; TP 508; UNCLASSIFIED DRUG; VITAMIN D;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL COUNT; CELL DIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENCHONDRAL OSSIFICATION; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FRACTURE HEALING; GROWTH PLATE; IN VITRO STUDY; MALE; NONHUMAN; OSSIFICATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

24,25-DIHYDROXYVITAMIN D 3; ALKALINE PHOSPHATASE; ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELLS, CULTURED; CHONDROCYTES; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; GROWTH PLATE; MALE; PEPTIDE FRAGMENTS; PHENOTYPE; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY; RIBS; SULFATES; THROMBIN; TIME FACTORS;

ORYCTOLAGUS CUNICULUS;

EID: 11144255822     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20145     Document Type: Article

References (29)

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