Treatment of resting zone chondrocytes with transforming growth factor-β1 induces differentiation into a phenotype characteristic of growth zone chondrocytes by downregulating responsiveness to 24,25-(OH)2D3 and upregulating responsiveness to 1,25-(OH)2D3

Bone

Volumn 23, Issue 5, 1998, Pages 465-470

  Schwartz, Z ^a,b   Sylvia, V L ^b   Liu, Y ^b   Dean, D D ^b   Boyan, B D ^b  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

1,25 dihydroxyvitamin D3; Cartilage; Chondrocytes; Differentiation; Transforming growth factor

Indexed keywords

CALCITRIOL; COLECALCIFEROL; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CARTILAGE CELL; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; NONHUMAN; OSSIFICATION;

24,25-DIHYDROXYVITAMIN D 3; ALKALINE PHOSPHATASE; ANIMALS; CALCITRIOL; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG SYNERGISM; PHENOTYPE; RATS; RATS, SPRAGUE-DAWLEY; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 0031659719     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(98)00132-X     Document Type: Article

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