IkB-α-specific transcript regulation by the C-terminal end of c-Rel

FEBS Letters

Volumn 579, Issue 1, 2005, Pages 141-144

  Iwai, Kazuyuki ^a   Lee, Byung Rho ^a   Hashiguchi, Masaaki ^a   Fukushima, Atsuki ^a   Iwashima, Makio ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

c Rel; IkB; IL 2; NF kB; TCR

Indexed keywords

CYTOKINE; I KAPPA B ALPHA; INTERLEUKIN 2; MESSENGER RNA; TRANSCRIPTION FACTOR REL;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE DELETION; GENE MUTATION; HUMAN; HUMAN CELL; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; WILD TYPE;

GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-2; JURKAT CELLS; MUTATION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-REL; RNA, MESSENGER; SEQUENCE DELETION; T-LYMPHOCYTES; TRANSFECTION;

GALLUS GALLUS;

EID: 11144255286     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2004.11.060     Document Type: Article

References (32)

1. Y. Yamamoto, and R.B. Gaynor IkappaB kinases: key regulators of the NF-kappaB pathway Trends Biochem. Sci. 29 2004 72 79
2. A. Hoffmann, A. Levchenko, M.L. Scott, and D. Baltimore The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation Science 298 2002 1241 1245
3. B.A. Hilliard, N. Mason, L. Xu, J. Sun, S.E. Lamhamedi-Cherradi, H.C. Liou, C. Hunter, and Y.H. Chen Critical roles of c-Rel in autoimmune inflammation and helper T cell differentiation J. Clin. Invest. 110 2002 843 850
4. F. Kontgen, R.J. Grumont, A. Strasser, D. Metcalf, R. Li, D. Tarlinton, and S. Gerondakis Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression Genes Dev. 9 1995 1965 1977
5. H.C. Liou, Z. Jin, J. Tumang, S. Andjelic, K.A. Smith, and M.L. Liou c-Rel is crucial for lymphocyte proliferation but dispensable for T cell effector function Int. Immunol. 11 1999 361 371
6. S. Gerondakis, A. Strasser, D. Metcalf, G. Grigoriadis, J.Y. Scheerlinck, and R.J. Grumont Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor Proc. Natl. Acad. Sci. USA 93 1996 3405 3409
7. A. Strasser, R.J. Grumont, M.L. Stanley, and S. Gerondakis The transcriptional regulator Rel is essential for antigen receptor-mediated stimulation of mature T cells but dispensable for positive and negative selection of thymocytes and T cell apoptosis Eur. J. Immunol. 29 1999 928 935
8. V.S. Shapiro, K.E. Truitt, J.B. Imboden, and A. Weiss CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites Mol. Cell Biol. 17 1997 4051 4058
9. P. Ghosh, T.H. Tan, N.R. Rice, A. Sica, and H.A. Young The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: c-Rel, p50, and p65 Proc. Natl. Acad. Sci. USA 90 1993 1696 1700
10. W.G. Butscher, C. Powers, M. Olive, C. Vinson, and K. Gardner Coordinate transactivation of the interleukin-2 CD28 response element by c-Rel and ATF-1/CREB2 J. Biol. Chem. 273 1998 552 560
11. S. Rao, S. Gerondakis, D. Woltring, and M.F. Shannon c-Rel is required for chromatin remodeling across the IL-2 gene promoter J. Immunol. 170 2003 3724 3731
12. S.C. Sun, P.A. Ganchi, D.W. Ballard, and W.C. Greene NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway Science 259 1993 1912 1915
13. T. Koike, H. Yamagishi, Y. Hatanaka, A. Fukushima, J.W. Chang, Y. Xia, M. Fields, P. Chandler, and M. Iwashima A novel ERK-dependent signaling process that regulates interleukin-2 expression in a late phase of T cell activation J. Biol. Chem. 278 2003 15685 15692
14. L. Venkataraman, S.J. Burakoff, and R. Sen FK506 inhibits antigen receptor-mediated induction of c-rel in B and T lymphoid cells J. Exp. Med. 181 1995 1091 1099
15. M. Iwashima Kinetic perspectives of T cell antigen receptor siganling Immunol. Rev. 192 2003 196 210
16. D. Carrasco, J. Cheng, A. Lewin, G. Warr, H. Yang, C. Rizzo, F. Rosas, C. Snapper, and R. Bravo Multiple hemopoietic defects and lymphoid hyperplasia in mice lacking the transcriptional activation domain of the c-Rel protein J. Exp. Med. 187 1998 973 984
17. Y. Fan, B. Rayet, and C. Gelinas Divergent C-terminal transactivation domains of Rel/NF-kappa B proteins are critical determinants of their oncogenic potential in lymphocytes Oncogene 23 2004 1030 1042
18. M. Zurovec, O. Petrenko, R. Roll, and P.J. Enrietto A chicken c-Rel-estrogen receptor chimeric protein shows conditional nuclear localization, DNA binding, transformation and transcriptional activation Oncogene 16 1998 3133 3142
19. B.L. Brizzard, R.G. Chubet, and D.L. Vizard Immunoaffinity purification of FLAG epitope-tagged bacterial alkaline phosphatase using a novel monoclonal antibody and peptide elution Biotechniques 16 1994 730 735
20. S. Yamasaki, M. Takamatsu, and M. Iwashima The kinase, SH3, and SH2 domains of Lck play critical roles in T-cell activation after ZAP-70 membrane localization Mol. Cell Biol. 16 1996 7151 7160
21. Y.H. Chien, M. Iwashima, K.B. Kaplan, J.F. Elliott, and M.M. Davis A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation Nature 327 1987 677 682
22. S. Ghosh, M.J. May, and E.B. Kopp NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses Annu. Rev. Immunol. 16 1998 225 260
23. B.S. Sylla, and H.M. Temin Activation of oncogenicity of the c-rel proto-oncogene Mol. Cell Biol. 6 1986 4709 4716
24. J. Kamens, P. Richardson, G. Mosialos, R. Brent, and T. Gilmore Oncogenic transformation by v-rel requires an amino-terminal activation domain Mol. Cell Biol. 10 1990 2840 2847
25. D.T. Starczynowski, J.G. Reynolds, and T.D. Gilmore Deletion of either C-terminal transactivation subdomain enhances the in vitro transforming activity of human transcription factor REL in chicken spleen cells Oncogene 22 2003 6928 6936
26. R.I. Scheinman, P.C. Cogswell, A.K. Lofquist, and A.S. Baldwin Jr Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids Science 270 1995 283 286
27. N. Auphan, J.A. DiDonato, C. Rosette, A. Helmberg, and M. Karin Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis Science 270 1995 286 290
28. S. Yamazaki, T. Muta, and K. Takeshige A novel IkappaB protein, IkappaB-zeta, induced by proinflammatory stimuli, negatively regulates nuclear factor-kappaB in the nuclei J. Biol. Chem. 276 2001 27657 27662
29. H. Kitamura, K. Kanehira, K. Okita, M. Morimatsu, and M. Saito MAIL, a novel nuclear I kappa B protein that potentiates LPS-induced IL-6 production FEBS Lett. 485 2000 53 56
30. H. Haruta, A. Kato, and K. Todokoro Isolation of a novel interleukin-1-inducible nuclear protein bearing ankyrin-repeat motifs J. Biol. Chem. 276 2001 12485 12488
31. Yamazaki, S., Muta, T., Matsuo, S., and Takeshige, K. (2004). Stimulus-specific induction of a novel NF-κB regulator, Ikappa B-zeta, via toll/interleukin-1 receptor is mediated by mRNA stabilization. J. Biol. Chem. November 2, 2004, e-pub
32. J.P. Northrop, K.S. Ullman, and G.R. Crabtree Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex J. Biol. Chem. 268 1993 2917 2923