Interleukin-10 mediates the protective effect of Linomide by reducing CXC chemokine production in endotoxin-induced liver injury

British Journal of Pharmacology

Volumn 143, Issue 7, 2004, Pages 865-871

  Li, Xiang ^a   Klintman, Daniel ^a   Sato, Tohru ^b   Hedlund, Gunnar ^c   Schramm, René ^d   Jeppsson, Bengt ^a   Thorlacius, Henrik ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b STANFORD UNIVERSITY   (United States)

^c Active Biotech Research AB   (Sweden)

^d SAARLAND UNIVERSITY   (Germany)

Author keywords

Adhesion; Chemokines; Endotoxin; Intravital microscopy; Linomide; Sepsis

Indexed keywords

CHEMOATTRACTANT; CHEMOKINE; COMPLEMENTARY DNA; ENDOTOXIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GALACTOSAMINE; IMMUNOMODULATING AGENT; INTERLEUKIN 10; MACROPHAGE INFLAMMATORY PROTEIN 2; ROQUINIMEX;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENDOTOXEMIA; IMMUNOMODULATION; LEUKOCYTE MIGRATION; LIVER CELL; LIVER INJURY; LIVER PERFUSION; LIVER PROTECTION; MALE; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPSIS;

ALANINE TRANSAMINASE; ANIMALS; APOPTOSIS; ASPARTATE AMINOTRANSFERASES; CHEMOKINES, CXC; ENDOTOXINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEPATITIS, TOXIC; HYDROXYQUINOLINES; IMMUNOLOGIC FACTORS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-10; INTERLEUKIN-16; LEUKOCYTES; LIVER; LIVER FUNCTION TESTS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 10844296610     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706015     Document Type: Article

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