Gene deletions by ends-in targeting in Drosophila melanogaster

Genetics

Volumn 168, Issue 3, 2004, Pages 1477-1489

  Xie, Heng B ^a   Golic, Kent G ^a  

^a UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; PROTEIN SIRTUIN 2; SILENT INFORMATION REGULATOR PROTEIN 2; SIRTUIN; UNCLASSIFIED DRUG;

ARTICLE; DNA STRAND BREAKAGE; DROSOPHILA MELANOGASTER; GENE DELETION; GENE TARGETING; INTERMETHOD COMPARISON; NULL ALLELE; PRIORITY JOURNAL;

ANIMALS; DNA TRANSPOSABLE ELEMENTS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE DELETION; GENE TARGETING; HISTONE DEACETYLASES; SIRTUINS; TUMOR SUPPRESSOR PROTEIN P53;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 10844286383     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: 10.1534/genetics.104.030882     Document Type: Article

References (23)

1. + gene is nonessential and has only minor effects on position-effect variegation. Genetics 163: 931-937.
2. DOLEZAL, T., M. GAZI, M. ZUROVEC and P. J. BRYANT, 2003 Genetic analysis of the ADGF multigene family by homologous recombination and gene conversion in Drosophila. Genetics 165: 653-666.
3. EGLI, D., A. SELVARAJ, H. YEPISKOPOSYAN, B. ZHANG, E. HAFEN et al., 2003 Knockout of 'metal-responsive transcription factor' MTF-1 in Drosophila by homologous recombination reveals its central role in heavy metal homeostasis. EMBO J. 22: 100-108.
4. ELMORE, T., R. IGNELL, J. R. CARLSON and D. P. SMITH, 2003 Targeted mutation of a Drosophila odor receptor defines receptor requirement in a novel class of sensillum. J. Neurosci. 23: 9906-9912.
5. GOLIC, K. G., and S. LINDQUIST, 1989 The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome. Cell 59: 499-509.
6. GONG, W. J., and K. G. GOLIC, 2003 Ends-out, or replacement, gene targeting in Drosophila. Proc. Natl. Acad. Sci. USA 100: 2556-2561.
7. GONG, W. J., and K. G. GOLIC, 2004 Genomic deletions of the Drosophila melanogaster hsp70 genes. Genetics 168: 1467-1476.
8. LANKENAU, S., T. BARNICKEL, J. MARHOLD, F. LYKO, B. M. MECHLER et al., 2003 Knockout targeting of the Drosophila Nap1 gene and examination of DNA repair tracts in the recombination products. Genetics 163: 611-623.
9. LINDSLEY, D. L., L. SANDLER, B. S. BAKER, A. T. C. CARPENTER, R. E. DENELL et al., 1972 Segmental aneuploidy and the genetic gross structure of the Drosophila genome. Genetics 71: 157-184.
10. LIU, H., and E. KUBLI, 2003 Sex-peptide is the molecular basis of the sperm effect in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 100: 9929-9933.
11. MARYON, E., and D. CARROLL, 1989 Degradation of linear DNA by a strand-specific exonuclease activity in Xenopus laevis oocytes. Mol. Cell. Biol. 9: 4862-4871.
12. NEWMAN, B. L., J. R. LUNDBLAD, Y. CHEN and S. M. SMOLIK, 2002 A Drosophila homologue of Sir2 modifies position-effect variegation but does not affect life span. Genetics 162: 1675-1685.
13. POSFAI, G., V. KOLISNYCHENKO, Z. BERECZKI and F. R. BLATTNER, 1999 Markerless gene replacement in Escherichia coli stimulated by a double-strand break in the chromosome. Nucleic Acids Res. 27: 4409-4415.
14. PRESTON, C. R., W. ENGELS and C. FLORES, 2002 Efficient repair of DNA breaks in Drosophila: evidence for single-strand annealing and competition with other repair pathways. Genetics 161: 711-720.
15. RONG, Y. S., and K. G. GOLIC, 2000 Gene targeting by homologous recombination in Drosophila. Science 288: 2013-2018.
16. RONG, Y. S., and K. G. GOLIC, 2001 A targeted gene knockout in Drosophila. Genetics 157: 1307-1312.
17. RONG, Y. S., and K. G. GOLIC, 2003 The homologous chromosome is an effective template for the repair of mitodc DNA double-strand breaks in Drosophila. Genetics 165: 1831-1842.
18. RONG, Y. S., S. W. TITEN, H. B. XIE, M. M. GOLIC, M. BASTIANI et al., 2002 Targeted mutagenesis by homologous recombination in D. melanogaster. Genes Dev. 16: 1568-1581.
19. ROSENBERG, M. I., and S. M. PARKHURST, 2002 Drosophila Sir2 is required for heterochromatic silencing and by euchromatic Hairy/E(Spl) bHLH repressors in segmentation and sex determination. Cell 109: 447-458.
20. RUBIN, G. M., and A. C. SPRADLING, 1983 Vectors for P element-mediated gene transfer in Drosophila. Nucleic Acids Res. 11: 6341-6351.
21. SEUM, C., D. PAULI, M. DELATTRE, Y. JAQUET, A. SPIERER et al., 2002 Isolation of Su(var)3-7 mutations by homologous recombination in Drosophila melanogaster. Genetics 161: 1125-1136.
22. SIEGAL, M. L., and D. L. HARTL, 1996 Transgene coplacement and high efficiency site-specific recombination with the Cre/loxP system in Drosophila. Genetics 144: 715-726.
23. SOGAME, N., M. KIM and J. M. ABRAMS, 2003 Drosophila p53 preserves genomic stability by regulating cell death. Proc. Natl. Acad. Sci. USA 100: 4696-4701.