A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons

Brain Research

Volumn 995, Issue 1, 2004, Pages 84-96

  Francis, Jonathan W ^a   Figueiredo, Dayse ^b   VanderSpek, Johanna C ^c   Ayala, Laura M ^a   Kim, Young Seon ^a   Remington, Mary P ^b   Young, Philip J ^d   Lorson, Christian L ^d   Ikebe, Shinichiro ^a   Fishman, Paul S ^b,e   Brown Jr , Robert H ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BALTIMORE VA MEDICAL CENTER   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MISSOURI   (United States)

^e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Diphtheria toxin; Protein delivery; Spinal muscular atrophy; Survival motor neuron (SMN) protein; Tetanus toxin fragment C

Indexed keywords

ANTIBODY; CYTOTOXIN; DIPHTHERIA TOXIN; EWING SARCOMA PROTEIN; HYBRID PROTEIN; NERVE PROTEIN; PEPTIDE; PEPTIDE FRAGMENT; PROTEIN ANTIBODY; PROTEIN DERIVATIVE; PROTEIN SDT; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; SMN PROTEIN (SPINAL MUSCULAR ATROPHY); SURVIVAL MOTOR NEURON PROTEIN; TETANUS ANTIBODY; TETANUS TOXIN; TETANUS TOXIN FRAGMENT C; TOXIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL; ANIMAL CELL; ANTIBODY LABELING; ARTICLE; CATALYSIS; CELL CULTURE; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG PROTEIN BINDING; DRUG PURIFICATION; EMBRYO; ENDOCYTOSIS; ESCHERICHIA COLI; GENE OVEREXPRESSION; GENETICS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; IN VITRO STUDY; INTERNALIZATION; MEMBRANE TRANSPORT; METABOLISM; MOLECULAR WEIGHT; MOTONEURON; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; PHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN TARGETING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; RAT; SPINAL MUSCULAR ATROPHY; WILD TYPE;

EID: 10744233853     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2003.09.063     Document Type: Article

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