The lipocalin 24p3, which is an essential molecule in IL-3 withdrawal-induced apoptosis, is not involved in the G-CSF withdrawal-induced apoptosis

European Journal of Haematology

Volumn 71, Issue 6, 2003, Pages 412-417

  Kamezaki, Kenjirou ^a,b   Shimoda, Kazuya ^a,b   Numata, Akihiko ^a,b   Aoki, Kenichi ^a,b   Kato, Kouji ^a,b   Takase, Ken ^a,b   Nakajima, Hideaki ^c   Ihara, Kenji ^a   Haro, Takashi ^a,b   Ishikawa, Fumihiko ^a,b   Imamura, Rie ^a,b   Miyamoto, Toshihiro ^a,b   Nagafuji, Koji ^a,b   Gondo, Hisashi ^a,b   Hara, Toshiro ^a   Harada, Mine ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

24p3; Apoptosis; Granulocyte colony stimulating factor; Interleukin 3; Stat3

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 3; LIPOCALIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVITY; CELL MATURATION; CONTROLLED STUDY; CYTOKINE RELEASE; GROWTH INHIBITION; HEMATOPOIETIC CELL; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACUTE-PHASE PROTEINS; ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; CULTURE MEDIA, CONDITIONED; GENE EXPRESSION; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELLS; HUMANS; INTERLEUKIN-3; MICE; NEUTROPHILS; ONCOGENE PROTEINS; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS;

EID: 10744233531     PISSN: 09024441     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0902-4441.2003.00160.x     Document Type: Article

References (15)

1. ISHIDA Y, AGATA Y, SHIBAHARA K, HONJO T. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. Embo J 1992;11:3887-3895.
2. KJELDSEN L, COWLAND JB, BORREGAARD N. Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse. Biochim Biophys Acta 2000;1482:272-283.
3. FLOWER DR. The lipocalin protein family: structure and function. Biochem J 1996;318 (Part 1):1-14.
4. DEVIREDDY LR, TEODORO JG, RICHARD FA, GREEN MR. Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation. Science 2001;293:829-834.
5. METCALF D. The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells. Nature 1989;339:27-30.
6. WELTE K, BONILLA MA, GILLIO AP, BOONE TC, POTTER GK, GABRILOVE JL, MOORE MA, O'REILLY RJ, SOUZA LM. Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates. J Exp Med 1987;165:941-948.
7. BARGE RM, DE KONING JP, POUWELS K, DONG F, LOWENBERG B, TOUW IP. Tryptophan 650 of human granulocyte colony-stimulating factor (G-CSF) receptor, implicated in the activation of JAK2, is also required for G-CSF-mediated activation of signaling complexes of the p21ras route. Blood 1996;87:2148-2153.
8. IHLE JN, NOSAKA T, THIERFELDER W, QUELLE FW, SHIMODA K. Jaks and Stats in cytokine signaling. Stem Cells 1997;15 Suppl. 1:105-112.
9. TIAN SS, LAMB P, SEIDEL HM, STEIN RB, ROSEN J. Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor. Blood 1994;84:1760-1764.
10. SHIMODA K, FENG J, MURAKAMI H, NAGATA S, WATLING D, ROGERS NC, STARK GR, KERR IM, IHLE JN. Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor. Blood 1997;90:597-604.
11. AZAM M, ERDJUMENT-BROMAGE H, KREIDER BL, XIA M, QUELLE F, BASU R, SARIS C, TEMPST P, IHLE JN, SCHINDLER C. Interleukin-3 signals through multiple isoforms of Stat5. Embo J 1995;14:1402-1411.
12. NAKAJIMA H, IHLE JN. Granulocyte colony-stimulating factor regulates myeloid differentiation through CCAAT/enhancer-binding protein epsilon. Blood 2001;98:897-905.
13. KINOSHITA T, YOKOTA T, ARAI K, MIYAJIMA A. Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors. Embo J 1995;14:266-275.
14. GARAY-ROJAS E, HARPER M, HRABA-RENEVEY S, KRESS M. An apparent autocrine mechanism amplifies the dexamethasone- and retinoic acid-induced expression of mouse lipocalin-encoding gene 24p3. Gene 1996;170:173-180.
15. TONG Z, WU X, KEHRER JP. Increased expression of the lipocalin 24p3 as an apoptotic mechanism for MK886. Biochem J 2003;372:203-210