Gene delivery to aortocoronary saphenous vein grafts in a large animal model of intimal hyperplasia

Journal of Thoracic and Cardiovascular Surgery

Volumn 127, Issue 1, 2004, Pages 27-33

  Petrofski, Jason A ^a   Hata, Jonathan A ^a   Gehrig, Thomas R ^a   Hanish, Steven I ^a   Williams, Matthew L ^a   Thompson, Richard B ^a   Parsa, Cyrus J ^a   Koch, Walter J ^a   Milano, Carmelo A ^a   Sellke, Frank W ^b   Kherani, Aftab R ^b   Kurlansky, Paul A ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR KINASE CARBOXYL TERMINUS; BETA GALACTOSIDASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTOCORONARY SAPHENOUS VEIN GRAFT; ARTERIOGRAPHY; ARTERY INTIMA PROLIFERATION; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DOG; EX VIVO STUDY; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC TRANSFECTION; GRAFT PATENCY; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SAPHENOUS VEIN GRAFT; STAINING; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS PARTICLE; VIRUS RECOMBINANT;

EID: 10744233479     PISSN: 00225223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2003.07.032     Document Type: Article

References (28)

1. Campeau L, Enjalbert M, Lesperance J, Vaislic C, Grondin CM, Bourassa MG. Atherosclerosis and late closure of aortocoronary saphenous vein grafts: sequential angiographic studies at 2 weeks, 1 year, 5 to 7 years, and 10 to 12 years after surgery. Circulation. 1983;68(3 Pt 2):111-7.
2. Bourassa MG, Campeau L, Lesperance J, Grondin CM. Changes in grafts and coronary arteries after saphenous vein aortocoronary bypass surgery: results at repeat angiography. Circulation. 1982;65(7 Pt 2): 90-7.
3. Newby AC, Zaltsman AB. Molecular mechanisms in intimal hyperplasia. J Pathol. 2000;190:300-9.
4. Souza DS, Dashwood MR, Tsui JC, Filbey D, Bodin L, Johansson B, et al. Improved patency in vein grafts harvested with surrounding tissue: results of a randomized study using three harvesting techniques, Ann Thorac Surg. 2002;73:1189-95.
5. Goldman S, Copeland J, Moritz T, Henderson W, Zadina K, Ovitt T, et al. Improvement in early saphenous vein graft patency after coronary artery bypass surgery with antiplatelet therapy: results of a Veterans Administration Cooperative Study. Circulation. 1988;77:1324-32.
6. Stein PD, Dalen JE, Goldman S, Schwartz L, Turpie AG, Theroux P. Antithrombotic therapy in patients with saphenous vein and internal mammary artery bypass grafts following percutaneous transluminal coronary angioplasty. Chest. 1992;102(4 Suppl):508S-15S.
7. Yoshimura S, Morishita R, Hayashi K, Yamamoto K, Nakagami H, Kaneda Y, et al. Inhibition of intimal hyperplasia after balloon injury in rat carotid artery model using cis-element "decoy" of nuclear factor-kappaB binding site as a novel molecular strategy. Gene Ther. 2001;8:1635-42.
8. Laukkanen MO, Kivela A, Rissanen T, Rutanen J, Karkkainen MK, Leppanen O, et al. Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloon-denuded rabbit aorta. Circulation. 2002;106:1999-2003.
9. Iaccarino G, Smithwick LA, Letkowitz RJ, Koch WJ. Targeting Gbeta gamma signaling in arterial vascular smooth muscle proliferation: a novel strategy to limit restenosis. Proc Natl Acad Sci U S A. 1999;96:3945-50.
10. Mangi AA, Dzau VJ. Gene therapy for human bypass grafts. Ann Med. 2001;33:153-5.
11. Morishita R, Gibbons GH, Horiuchi M, Ellison KE, Nakama M, Zhang L, et al. A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo. Proc Natl Acad Sci U S A. 1995;92:5855-9.
12. White DC, Hata JA, Shah AS, Glower DD, Lefkowitz RJ, Koch WJ. Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction. Proc Natl Acad Sci U S A. 2000;97:5428-33.
13. Davies MG, Huynh TT, Fulton GJ, Lefkowitz RJ, Svendsen E, Hagen PO, et al. G protein signaling and vein graft intimal hyperplasia: reduction of intimal hyperplasia in vein grafts by a Gbetagamma inhibitor suggests a major role of G protein signaling in lesion development. Arterioscler Thromb Vasc Biol. 1998;18:1275-80.
14. Silver MD, MacGregor DC, Agarwal VK, Lixfeld W. Aortocoronary bypass graft: early histologic changes in dogs. Can J Surg. 1973;16:246-51.
15. Brody WR, Angell WW, Kosek JC. Histologic fate of the venous coronary artery bypass in dogs. Am J Pathol. 1972;66:111-9.
16. Silver MD, Wilson GJ, Lixfeld W, Trimble AS, MacGregor DC. Aortocoronary bypass graft in dogs: late histologic changes. Pathology. 1976;8:343-51.
17. Tsukioka K, Suzuki J, Fujimori M, Wada Y, Yamaura K, Ito K, et al. Expression of matrix metalloproteinases in cardiac allograft vasculopathy and its attenuation by anti MMP-2 ribozyme gene transfection. Cardiovasc Res. 2002;56:472-8.
18. Huang J, Kontos CD. PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects. J Biol Chem. 2002;277:10760-6.
19. Koch WJ, Inglese J, Stone WC, Lefkowitz RJ. The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. J Biol Chem. 1993;268:8256-60.
20. Koch WJ, Hawes BE, Inglese J, Luttrell LM, Lefkowitz RJ. Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling. J Biol Chem. 1994;269:6193-7.
21. Iaccarino G, Koch WJ. G beta gamma-mediated signaling: new therapeutic target for proliferative vascular disease. IUBMB Life. 1999;48:257-61.
22. Chiu-Pinheiro CK, O'Brien T, Katusic ZS, Bonilla LF, Hamner CE, Schaff HV. Gene transfer to coronary artery bypass conduits. Ann Thorac Surg. 2002;74:1161-6.
23. Chester AH, Buttery LD, Borland JA, Springall DR, Rothery S, Severs NJ, et al. Structural, biochemical and functional effects of distending pressure in the human saphenous vein: implications for bypass grafting. Coron Artery Dis. 1998;9:143-51.
24. Hausmann H, Merker HJ, Hetzer R. Pressure controlled preparation of the saphenous vein with papaverine for aortocoronary venous bypass. J Card Surg. 1996;11:155-62.
25. Kennedy JH, Lever MJ, Addis BJ, Paneth M. Changes in vein interstitium following distension for aortocoronary bypass. J Card Surg. 1989;30:992-5.
26. Angelini GD, Passani SL, Breckenridge IM, Newby AC. Nature and pressure dependence of damage induced by distension of human saphenous vein coronary artery bypass grafts. Cardiovasc Res. 1987;21:902-7.
27. Ehsan A, Mann MJ, Dell'Acqua G, Dzau VJ. Long-term stabilization of vein graft wall architecture and prolonged resistance to experimental atherosclerosis after E2F decoy oligonucleotide gene therapy; J Thorac Cardiovasc Surg. 2001;121:714-22.
28. Muir WW, Hubbell JAE, Skarda RT, Bednarski RM. The handbook of veterinary anesthesia. 3rd ed. New York: Mosby; 2000.