L-Arginine Depletion in Preeclampsia Orients Nitric Oxide Synthase Toward Oxidant Species

Hypertension

Volumn 43, Issue 3, 2004, Pages 614-622

  Noris, Marina ^a   Todeschini, Marta ^a   Cassis, Paola ^a   Pasta, Fabio ^b   Cappellini, Anna ^b   Bonazzola, Samantha ^a   Macconi, Daniela ^a   Maucci, Raffaella ^a   Porrati, Francesca ^a   Benigni, Ariela ^a   Picciolo, Claudio ^b   Remuzzi, Giuseppe ^c  

^a MARIO NEGRI INST PHARMACOL RES   (Italy)

^b SAN GERARDO HOSPITAL   (Italy)

^c OSPEDALI RIUNITI   (Italy)

Author keywords

Arginine; Nitric oxide synthase; Nitrites; Oxidative stress; Preeclampsia

Indexed keywords

3 NITROTYROSINE; 4 HYDROXYNONENAL; AMINO ACID TRANSPORTER; ARGINASE; ARGINASE 2; ARGININE; CITRULLINE; LYSINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; ORNITHINE; OXIDIZING AGENT; PEROXIDASE; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIOAVAILABILITY; CHORION VILLUS; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; OXIDATIVE STRESS; PLACENTA PERFUSION; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; TISSUE INJURY; UMBILICAL CORD BLOOD; VASODILATATION; WESTERN BLOTTING;

ADULT; AMINO ACID TRANSPORT SYSTEMS, BASIC; ARGINASE; ARGININE; FEMALE; HUMANS; LIPID PEROXIDATION; MATERNAL-FETAL EXCHANGE; NADPH DEHYDROGENASE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PEROXYNITROUS ACID; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; REACTIVE NITROGEN SPECIES;

EID: 10744232765     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000116220.39793.c9     Document Type: Article

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