IL4-589C/T polymorphism and IgE levels in severe malaria

Acta Tropica

Volumn 90, Issue 2, 2004, Pages 205-209

  Verra, Federica ^a,b   Luoni, Gaia ^a,f   Calissano, Carlo ^a,c   Troye Blomberg, Marita ^c   Perlmann, Peter ^c   Perlmann, Hedvig ^c   Arcà, Bruno ^a,d   Sirima, Bienvenu Sodiomon ^e   Konaté, Amadou ^e   Coluzzi, Mario ^a,b   Kwiatkowski, Dominic ^f   Modiano, David ^a,b  

^a WHO Collaborating Ctr for Nutrition   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e Ctr Natl Rech/Form Paludisme   (Burkina Faso)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Cytokines; Plasmodium falciparum specific IgE; Severe malaria; Total IgE; West Africa

Indexed keywords

IMMUNOGLOBULIN E;

MALARIA;

ADOLESCENT; AFRICA; ALLELE; ARTICLE; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; DNA POLYMORPHISM; ENDEMIC DISEASE; FEMALE; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALARIA; MALE; NEWBORN; PLASMODIUM FALCIPARUM; PROMOTER REGION;

BURKINA FASO; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; HUMANS; IMMUNOGLOBULIN E; INFANT; INTERLEUKIN-4; MALARIA; POLYMORPHISM, GENETIC; VARIATION (GENETICS);

PLASMODIUM FALCIPARUM;

EID: 10744232364     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actatropica.2003.11.014     Document Type: Article

References (20)

1. Allan R.J., Beattie P., Bate C., Van Hensbroek M.B., Morris-Jones S., Greenwood B.M., Kwiatkowski D. Strain variation in tumor necrosis factor induction by parasites from children with acute falciparum malaria. Infect. Immun. 63:1995;1173-1175.
2. Borish L., Mascali J.J., Klinnert M., Leppert M., Rosenwasser L.J. SSC polymorphisms in interleukin genes. Hum. Mol. Genet. 3:1994;1710.
3. Esposito F., Lombardi S., Modiano D., Zavala F., Reeme J., Lamizana L., Coluzzi M., Nussenzweig R.S. Prevalance and levels of antibodies to the circumsporozoite protein of Plasmodium falciparum in an endemic area and their relationship to resistance against malaria infection. Trans. R. Soc. Trop. Med. Hyg. 82:1988;827-832.
4. Flori L., Kumulungui B., Aucan C., Esnault C., Traoré A.S., Fumoux F., Rihet P. Linkage and association between Plasmodium falciparum blood infection levels and chromosome 5q31-q33. Genes Immun. 4:2003;265-268.
5. Gupta S., Hill A.V.S., Kwiatkowski D., Greenwood A.M., Greenwood B.M., Day K.P. Parasite virulence and disease patterns in Plasmodium falciparum malaria. Proc. Natl. Acad. Sci. U.S.A. 91:1994;3715-3719.
6. Luoni G., Verra F., Arcà B., Sirima B.S., Troye-Blomberg M., Coluzzi M., Kwiatkowski D., Modiano D. Antimalarial antibody levels and IL-4 polymorphism in the Fulani of West Africa. Genes Immun. 2:2001;411-414.
7. Maeno Y., Perlmann P., Perlmann H., Kusuhara Y., Taniguchi K., Nakabayashi T., Win K., Looareesuwan S., Aikawa M. IgE deposition in brain microvessels and on parasitized erythrocytes from cerebral malaria patients. Am. J. Trop. Med. Hyg. 63:2000;128-132.
8. Marsh D.G., Neely J.D., Breazeale D.R., Ghosh B., Freidhoff L.R., Ehrlich-Kautzky E., Schou C., Krishnaswamy G., Beaty T.H. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science. 264:1994;1152-1156.
9. Modiano D., Petrarca V., Sirima B.S., Bosman A., Nebie I., Diallo D., Lamizana L., Esposito F., Coluzzi M. Plasmodium falciparum malaria in sympatric ethnic groups of Burkina Faso, West Africa. Parassitologia. 37:1995;255-259.
10. Modiano D., Petrarca V., Sirima B.S., Nebie I., Diallo D., Esposito F., Coluzzi M. Different response to Plasmodium falciparum malaria in West African sympatric ethnic groups. Proc. Natl. Acad. Sci. U.S.A. 93:1996;13206-13211.
11. Miller S.A., Dykes D.D., Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucl. Acids Res. 16:1988;1215.
12. Mshana R.N., Boulandi J., Mshana N.M., Mayombo J., Mendome G. Cytokines in the pathogenesis of malaria levels of IL-Ibeta, IL-4, IL-6, TNF-α and IFN-gamma in plasma of healthy individuals and malaria patients in a holoendemic area. J. Clin. Lab. Immunol. 34:1991;131-139.
13. Nacher M., Singhasivanon P., Gay F., Silachamroon U., Looareesuwan S. Case-control studies on host factors in severe malaria. Trends Parasitol. 17:2001;253-254.
14. Perlmann H., Helmby H., Hagstedt M., Carlson J., Larsson P.H., Troye-Blomberg M., Perlmann P. IgE elevation and IgE anti-malarial antibodies in Plasmodium falciparum malaria: association of high IgE levels with cerebral malaria. Clin. Exp. Immunol. 97:1994;284-292.
15. Perlmann P., Perlmann H., Wahlin Flyg B.W., Hagstedt M., Elghazali G., Worku S., Fernandez V., Rutta A.S., Troye-Blomberg M. Immunoglobulin E, a pathogenic factor in Plasmodium falciparum malaria. Infect. Immun. 65:1997;116-121.
16. Perlmann P., Perlmann H., ElGhazali G., Troye-Blomberg M. IgE and tumor necrosis factor in malaria infection. Immunol. Lett. 65:1999;29-33.
17. Petrarca V., Petrangeli G., Rossi P., Sabatinelli G. Etude chromosomique d'Anopheles gambiae et Anopheles arabiensis a Ouagadougou (Burkina Faso) et dans quelques villages voisins. Parassitologia. 28:1986;41-61.
18. Rihet P., Traoré Y., Abel L., Aucan C., Traoré-Leroux T., Fumoux F. Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33. Am. J. Hum. Genet. 63:1998;498-505.
19. Rosenwasser L.J., Klemm D.J., Dresback J.K., Inamura H., Mascali J.J., Klinnert M., Borish L. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin. Exp. Allergy. 25(Suppl. 2):1995;74-78.
20. Troye-Blomberg M., Riley E.M., Kabilan L., Holmberg M., Perlmann H., Andersson U., Heusser C.H., Perlmann P. Production by activated human T cells of interleukin 4 but not interferon-γ is associated with elevated levels of serum antibodies to activating malaria antigens. Proc. Natl. Acad. Sci. U.S.A. 87:1990;5484-5488.