Antimalarial antibody levels and IL4 polymorphism in the Fulani of West Africa

Genes and Immunity

Volumn 2, Issue 7, 2001, Pages 411-414

  Luoni, G ^a   Verra, F ^a   Arca B ^a   Sirima, B S ^b   Troye Blomberg, M ^c   Coluzzi, M ^a   Kwiatkowski, D ^d   Modiano, D ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b MINISTÈRE DE LA SANTÉ   (Burkina Faso)

^c STOCKHOLM UNIVERSITY   (Sweden)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Ethnic groups; Interleukin 4; Malarial immunity; Polymorphism

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN G; INTERLEUKIN 4; PARASITE ANTIGEN;

AFRICA; ANIMAL; ARTICLE; DISEASE PREDISPOSITION; ETHNIC GROUP; ETHNOLOGY; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; IMMUNOLOGY; MALARIA; MALE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PROMOTER REGION;

AFRICA, WESTERN; ANIMALS; ANTIBODIES; ANTIGENS, PROTOZOAN; DISEASE SUSCEPTIBILITY; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-4; MALARIA; MALE; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS);

EID: 0035513854     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363797     Document Type: Article

References (20)

1. Modiano D, Petrarca V, Sirima BS et al. Plasmodium falciparum malaria in sympatric ethnic groups of Burkina Faso, West Africa. Parassitologia 1995; 37: 255-259.
2. Modiano D, Petrarca V, Sirima BS et al. Different response to Plasmodium falciparum malaria in West African sympatric ethnic groups. Proc Natl Acad Sci USA 1996; 93: 13206-13211.
3. Modiano D, Luoni G, Petrarca V et al. HLA class I in three West African ethnic groups: genetic distances from sub-Saharan and Caucasoid populations. Tissue Antigens 2001; 57: 128-137.
4. Modiano D, Luoni G, Sirima BS et al. The lower susceptibility to Plasmodium falciparum malaria of Fulani of Burkina Faso (West Africa) is associated with low frequencies of classical malaria resistance alleles. Trans R Soc Trop Med Hyg 2000; 95: 1-4.
5. Modiano D, Chiucchiuini A, Petrarca V et al. Humoral response to Plasmodium falciparum Pf155/ring-infected erythrocyte surface antigen and Pf332 in three sympatric ethnic groups of Burkina Faso. Am J Trop Med Hyg 1998; 58: 220-224.
6. Modiano D, Chiucchiuini A, Petrarca V et al. Interethnic differences in the humoral response to non-repetitive regions of the Plasmodium falciparum circumsporozoite protein. Am J Trop Med Hyg 1999; 61: 663-667.
7. Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rew Immunol 1989; 7: 145-173.
8. Marsh DG, Neely JD, Breazeale DR et al. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994; 20: 1152-1156.
9. Marsh DG, Neely JD, Breazeale DR et al. Total serum IgE levels and chromosome 5q. Clin Exp Allergy 1995; 25: 79-83.
10. Troye-Blomberg M, Riley E.M, Kabilan L et al. Production by activated human T cells of interleukin 4 but not interferon-γ is associated with elevated levels of serum antibodies to activating malaria antigens. Proc Natl Acad Sci USA 1990; 87: 5484-5488.
11. Rihet P, Abel L, Traore Y, Traore-Leroux T, Aucan C, Fumoux F. Human malaria: segregation analysis of blood infection levels in a suburban area and a rural area in Burkina Faso. Genet Epidemiol 1998; 15: 435-450.
12. Rihet P, Traore Y, Abel L, Aucan C, Traore-Leroux T, Fumoux F. Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33. Am J Hum Genet 1998; 63: 2-9.
13. Borish L, Mascali JJ, Klinnert M, Leppert M, Rosenwasser LJ. SSC polymorphisms in interleukin genes. Hum Mol Genet 1995; 4: 974.
14. Rosenwasser LJ, Klemm DJ, Dresback JK et al. Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy 1995; 25: 74-78.
15. Suzuki I, Yamaguchi E, Hizawa N, Itoh A, Kawakami Y. A new polymorphism in the 5′ flanking region of the human interleukin (IL)-4 gene. Immunogenetics 1999; 49: 738-739.
16. Elghazali G, Perlmann H, Rutta ASM, Perlmann P, Troye-Blomberg M. Elevated plasma levels of IgE in Plasmodium falciparum-primed individuals reflect an increased ratio of IL-4 to Interferon-gamma (IFN-γ)-producing cells. Clin Exp Immunol 1997; 109: 84-89.
17. Taylor-Robinson AW, Phillips RS, Severn A, Moncada S, Liew FY. The role of TH1 and TH2 cells in a rodent malaria infection. Science 1993; 25: 1931-1934.
18. Taylor-Robinson AW. Immunoregulation of malarial infection: balancing the vices and virtues. Int J Parasitol 1998; 28: 135-148.
19. Winkler S, Willheim M, Baier K, Graninger W, Kremsner PG. Frequency of cytokine-producing CD4-CD8-peripheral blood mononuclear cells in patients with Plasmodium falciparum malaria. Eur Cytokine Netw 1999; 10: 155-160.
20. Loots GG, Locksley RM, Blankespoor CM et al. Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. Science 2000; 7: 136-140.