Insulin Promoter Factor-1 Mutations and Diabetes in Trinidad: Identification of a Novel Diabetes-Associated Mutation (E224K) in an Indo-Trinidadian Family

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 2, 2004, Pages 971-978

  Cockburn, Brian N ^a,c   Bermano, Giovanna ^b   Boodram, Laura Lee G ^a,c   Teelucksingh, Surujpal ^a   Tsuchiya, Takafumi ^c   Mahabir, Deepak ^d   Allan, Andrew B ^b   Stein, Roland ^e   Docherty, Kevin ^b   Bell, Graeme I ^c  

^a UNIVERSITY OF THE WEST INDIES   (Trinidad and Tobago)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c UNIVERSITY OF CHICAGO   (United States)

^d Ministry of Health Trinidad and Tobago   (Trinidad and Tobago)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; LEUCINE; TRANSCRIPTION FACTOR PDX 1;

5' UNTRANSLATED REGION; ADULT; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; FAMILIAL DISEASE; FAMILY HISTORY; FEMALE; GENE DUPLICATION; GENE IDENTIFICATION; GENE MUTATION; GENE SILENCING; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; MAJOR CLINICAL STUDY; MALE; MATURITY ONSET DIABETES MELLITUS; MISSENSE MUTATION; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS; SEGREGATION DISTORTION; TRANSACTIVATION;

ADULT; AFRICA; AGED; CELL LINE; DIABETES MELLITUS; FEMALE; FOUNDER EFFECT; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; GLUTAMIC ACID; HAPLOTYPES; HELA CELLS; HOMEODOMAIN PROTEINS; HUMANS; INDIA; LYSINE; MALE; MIDDLE AGED; MUTATION; MUTATION, MISSENSE; PEDIGREE; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRINIDAD AND TOBAGO;

EID: 10744231201     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-031282     Document Type: Article

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