Conformation of the trypanocidal pharmaceutical suramin in its free and bound forms: Transferred nuclear overhauser studies

Biochemistry

Volumn 36, Issue 46, 1997, Pages 14202-14217

  Polenova, Tatyana ^a   Iwashita, Takashi ^a   Palmer III, Arthur G ^b   McDermott, Ann E ^a  

^a Columbia University ^*  (United States)

^b SUNTORY LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOGLYCERATE KINASE; SURAMIN;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG CONFORMATION; DRUG PROTEIN BINDING; MOLECULAR DYNAMICS; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SACCHAROMYCES CEREVISIAE; TRYPANOSOMA BRUCEI;

ANIMALS; ANTI-HIV AGENTS; ANTINEOPLASTIC AGENTS; COMPUTER SIMULATION; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHOGLYCERATE KINASE; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SURAMIN; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0030726350     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970297m     Document Type: Article

References (51)

1. Borchert, T. A., Pratt, K., Zeelen, J. P., Callens, M., Noble, M. E. M., Opperdoes, F. R., Michels, P. M., & Wierenga, R. K. (1992) Eur. J. Biochem. 211, 703-710.
2. Boyle, H. A., Fairbrother, W. J., & Williams, R. J. P. (1989) Eur. J. Biochem. 184, 535-543.
3. Brisson, J., & Brissé, F. (1985) Can. J. Chem 63, 3390-3397.
4. Campbell, A. P., & Sykes, B. D. (1993) Annu. Rev. Biophys. Biomol. Struct. 22, 99-122.
5. Carr, H. Y., & Purcell, E. M. (1954) Phys. Rev. 94, 630-638.
6. Clanton, D. J., Moran, R. A., McMahon, J. B., Weislow, O. S., Buckheit, R. W., Hollingshead, M. G., Ciminale, V., Felber, B. K., Pavlakis, G. N., & Bader, J. P. (1992) AIDS 5, 771-781.
7. Collins, J. M., Klecker, R. W., Yarchoan, R., Lane, H. C., Fauci, A. S., Redfield, R. R., Broder, S., & Myers, C. E. (1986) J. Clin. Pharmacol. 26, 22-26.
8. Fairlamb, A. H., & Bowman, I. B. R. (1980) Mol. Biochem. Parasitol. 1, 315-333.
9. Farrow, N. A., Muhandiram, R., Singer, A. U., Pascal, S. M., Kay, C. M., Gish, G., Shoelson, S. E., Pawson, T., Forman-Kay, J. D., & Kay, L. E. (1994) Biochemistry 33, 5984-6003.
10. Fourneau, V., Tréfouel, J., & Vallée, J. (1924) Ann. Inst. Pasteur 38, 8-1.
11. Ganis, P., Avitabile, G., Migdal, S., & Goodman, M. (1971) J. Am. Chem. Soc. 93, 3328-3331.
12. Goeddel, D. V. (1990) Gene expression technology, Academic Press, San Diego.
13. Hammes, G. G., & Schimmel, P. R. (1970) in Enzymes (Boyer, P. D., Eds.) pp 109, Academic Press, New York.
14. Harte, D. (1990) Parasitology Today 5, 117-120.
15. Ishima, R., & Nagayama, K. (1995) Biochemistry 34, 3162-3171.
16. Jentsch, K., Hunsmann, G., Hartmann, H., & Nickel, P. (1987) J. Gen. Virol. 68, 2183-2192.
17. Kashino, S., Ito, K., & Haisa, M. (1979) Bull. Chem. Soc. Jpn. 52, 365-369.
18. Kohda, D., Kawai, G., Yokoyama, S., Kawakami, M., Mizushima, S., & Miyazawa, T. (1987) Biochemistry 26, 6531-6538.
19. Landy, S. B., & Rao, B. D. N. (1989) J. Magn. Reson. 81, 371-377.
20. Lee, W., & Krishna, N. R. (1992) J. Magn. Reson. 98, 36-48.
21. Lipari, G., & Szabo, A. (1980) Biophys. J. 30, 489-506.
22. Lipari, G., & Szabo, A. (1982a) J. Am. Chem. Soc. 104, 4546-4559.
23. Lipari, G., & Szabo, A. (1982b) J. Am. Chem. Soc. 104, 4559-4570.
24. Lippens, G., Dhalluin, C., & Wieruszeski, J.-M. (1995) J. Biomol. NMR 5, 327.
25. Lippens, G. M., Cerf, C., & Hallenga, K. (1992) J. Magn. Reson. 99, 268-281.
26. Macura, S., & Ernst, R. R. (1980) Mol. Phys. 41, 95-117.
27. Marion, D., & Wüthrich, K. (1983) Biochem. Biophys. Res. Commun. 113, 961-914.
28. Meiboom, S., & Gill, D. (1958) Rev. Sci. Instrum. 29, 688-691.
29. Middaugh, C. R., Mach, H., Burke, C. J., Volkin, D. B., Dabora, J. M., Tsai, P. K., Bruner, M. W., Ryan, J. A., & Marfia, K. E. (1992) Biochemistry 31, 9016-9024.
30. Misset, O., & Opperdoes, F. R. (1987) Eur. J. Biochem. 162, 493-500.
31. Mohan, P. (1993) Drug Dev. Res. 29, 1-17.
32. Ni, F. (1994) Progr. NMR Spectr. 26, 517-606.
33. Nickel, V. P., Haack, H.-J., Widjaja, H., Ardanuy, U., Gurgel, C., Düwel, D., Loewe, H., & Raether, W. (1986) Arzneim.-Forsch./ Drug Res. 36 (II), 1153-1157.
34. Opperdoes, F. (1987) Annu. Rev. Microbiol. 41, 127-151.
35. Otting, G., Grutter, R., Leupin, W., Minganti, C., Ganesh, K. N., Sproat, B. S., Gait, M. J., & Wüthrich, K. (1987) Eur. J. Biochem. 166, 215-220.
36. Palmer, A., Rance, M., & Wright, P. (1991) J. Am. Chem. Soc. 113, 4371-4380.
37. Palmer, A. G., III, Hochstrasser, R. A., Millar, D. P., Rance, M., & Wright, P. E. (1993) J. Am. Chem. Soc. 115, 6333-6345.
38. Palmer, A. G., III, Williams, J., & McDermott, A. (1996) J. Phys. Chem. 100, 13293-13310.
39. Peng, J. W. & Wagner, G. (1992a) Biochemistry 31, 8571-8586.
40. Peng, J. W. & Wagner, G. (1992b) J. Magn. Reson. 98, 308-332.
41. Piotto, M., Saudek, V., & Sklenár, V. (1992) J-Bio NMR 2, 661-665.
42. Polenova, T. (1997) in Conformational Analysis of Pharmaceutical Suramin Free and in the Presence of Its Target Receptors by Solution NMR: What We Learned from and about Transferred NOESY, Ph.D. Thesis, Columbia University, New York, 341 pp.
43. Schreiber, G., & Fersht, A. R. (1993) Biochemistry 32, 5145-5150.
44. Schurr, J. M., Babcock, H. P., & Fujimoto, B. S. (1994) J. Magn. Reson., Ser. B 105, 211-224.
45. Shaka, A. J., Keeler, J., & Freeman, R. (1983) J. Magn. Reson. 52, 335-338.
46. Sharp, K., Fine, R., & Honig, B. (1987) Science 236, 1460-1463.
47. Sklenár, V., Piotto, M., Leppik, R., & Saudek, V. (1993) J. Magn. Reson. 102, 241-245.
48. Stein, C. (1993) Cancer Res. 53, 2239-2248.
49. Vansterkenburg, E., Coppens, I., Wilting, J., Bos, O., Fischer, M., Janssen, L., & Opperdoes, F. (1993) Acta Tropica 54, 237-250.
50. Wallis, R., Moore, G. R., James, R., & Kleanthous, C. (1995) Biochemistry 34, 13743-13750.
51. Willson, M., Callens, M., Kuntz, D. A., Perié, J., & Opperdoes, F. R. (1993) Mol. Biochem. Parasitol. 59, 201-210.