-
1
-
-
0027382941
-
Cancer of the ovary
-
Cannistra, S. A. Cancer of the ovary. N. Engl. J. Med., 329: 1550-1559, 1993.
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 1550-1559
-
-
Cannistra, S.A.1
-
2
-
-
0027459228
-
Taxol in ovarian cancer
-
Runowicz, C. D., Wiernik, P. H., Einzig, A. I., Goldberg, G. L., and Horwitz, S. B. Taxol in ovarian cancer. Cancer (Phila.), 71: 1591-1596, 1993.
-
(1993)
Cancer (Phila.)
, vol.71
, pp. 1591-1596
-
-
Runowicz, C.D.1
Wiernik, P.H.2
Einzig, A.I.3
Goldberg, G.L.4
Horwitz, S.B.5
-
4
-
-
84975525035
-
Clinical applications of research on angiogenesis
-
Folkman, J. Clinical applications of research on angiogenesis. N. Engl. J. Med., 333: 1757-1763, 1996.
-
(1996)
N. Engl. J. Med.
, vol.333
, pp. 1757-1763
-
-
Folkman, J.1
-
5
-
-
0031691329
-
Anti-angiogenic therapies in cancer clinical trials
-
Zhang, H. T., and Harris, A. L. Anti-angiogenic therapies in cancer clinical trials. Exp. Opin. Investig. Drugs, 7: 1629-1655, 1998.
-
(1998)
Exp. Opin. Investig. Drugs
, vol.7
, pp. 1629-1655
-
-
Zhang, H.T.1
Harris, A.L.2
-
6
-
-
0030018743
-
A system approach to cancer therapy
-
Teicher, B. A. A system approach to cancer therapy. Cancer Metastasis Rev., 15: 247-272, 1996.
-
(1996)
Cancer Metastasis Rev.
, vol.15
, pp. 247-272
-
-
Teicher, B.A.1
-
7
-
-
0031945505
-
Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the anti-tumor activity of cisplatin in ovarian carcinoma xenografts
-
Giavazzi, R., Garofalo, A., Ferri, C., Lucchini, V., Bone, E. A., Chiari, S., Brown, P. D., Nicoletti, M. I., and Taraboletti, G. Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the anti-tumor activity of cisplatin in ovarian carcinoma xenografts. Clin. Cancer Res., 4: 985-992, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 985-992
-
-
Giavazzi, R.1
Garofalo, A.2
Ferri, C.3
Lucchini, V.4
Bone, E.A.5
Chiari, S.6
Brown, P.D.7
Nicoletti, M.I.8
Taraboletti, G.9
-
8
-
-
0029044875
-
Tumor angiogenesis in advanced stage ovarian carcinoma
-
Hollingsworth, H. C., Kohn, E. C., Steinberg, S. M., Rothenberg, M. L., and Merino, M. J. Tumor angiogenesis in advanced stage ovarian carcinoma. Am. J. Pathol., 147: 33-41, 1995.
-
(1995)
Am. J. Pathol.
, vol.147
, pp. 33-41
-
-
Hollingsworth, H.C.1
Kohn, E.C.2
Steinberg, S.M.3
Rothenberg, M.L.4
Merino, M.J.5
-
9
-
-
0032995287
-
The prognostic significance of angiogenesis in epithelial ovarian carcinoma
-
Alvarez, A. A., Krigman, H. R., Whitaker, R. S., Dodge, R. K., and Rodriguez, G. C. The prognostic significance of angiogenesis in epithelial ovarian carcinoma. Clin. Cancer Res., 5: 587-591, 1999.
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 587-591
-
-
Alvarez, A.A.1
Krigman, H.R.2
Whitaker, R.S.3
Dodge, R.K.4
Rodriguez, G.C.5
-
10
-
-
0028153737
-
Vascular permeability factor gene expression in normal and neoplastic human ovaries
-
Olson, T. A., Mohanraj, D., Carson, L. F., and Ramakrishnan, S. Vascular permeability factor gene expression in normal and neoplastic human ovaries. Cancer Res., 54: 276-280, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 276-280
-
-
Olson, T.A.1
Mohanraj, D.2
Carson, L.F.3
Ramakrishnan, S.4
-
11
-
-
0030838780
-
Angiogenic protein expression in advanced epithelial ovarian cancer
-
Barton, D. P., Cai, A., Wendt, K., Young, M., Gamero, A., and De Cesare, S. Angiogenic protein expression in advanced epithelial ovarian cancer. Clin. Cancer Res., 3: 1579-1586, 1997.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 1579-1586
-
-
Barton, D.P.1
Cai, A.2
Wendt, K.3
Young, M.4
Gamero, A.5
De Cesare, S.6
-
12
-
-
0035352721
-
Angiogenesis: Pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs
-
Fox, S. B., Gasparini, G., and Harris, A. L. Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs. Lancet Oncol., 2: 278-289, 2001.
-
(2001)
Lancet Oncol.
, vol.2
, pp. 278-289
-
-
Fox, S.B.1
Gasparini, G.2
Harris, A.L.3
-
13
-
-
0032852528
-
Molecular and biological properties of vascular endothelial growth factor
-
Ferrara, N. Molecular and biological properties of vascular endothelial growth factor. J. Mol. Med., 77: 527-543, 1999.
-
(1999)
J. Mol. Med.
, vol.77
, pp. 527-543
-
-
Ferrara, N.1
-
14
-
-
0029004025
-
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis
-
Dvorak, H. F., Brown, L. F., Detmar, M., and Dvorak, A. M. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am. J. Pathol., 146: 1029-1039, 1995.
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 1029-1039
-
-
Dvorak, H.F.1
Brown, L.F.2
Detmar, M.3
Dvorak, A.M.4
-
15
-
-
0030484706
-
Vascular targeting of solid and ascites tumours with antibodies to vascular endothelial growth factor
-
Ke-Lin, Qu-Hong, Nagy, J. A., Eckelhoefer, I. A., Masse, E. M., Dvorak, A. M., and Dvorak, H. F. Vascular targeting of solid and ascites tumours with antibodies to vascular endothelial growth factor. Eur. J. Cancer, 32A: 2467-2473, 1996.
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 2467-2473
-
-
Ke-Lin, Q.-H.1
Nagy, J.A.2
Eckelhoefer, I.A.3
Masse, E.M.4
Dvorak, A.M.5
Dvorak, H.F.6
-
16
-
-
0005419856
-
Significant expression of vascular endothelial growth factor/vascular permeability factor in mouse ascites tumors
-
Luo, J. C., Yamaguchi, S., Shinkai, A., Shitara, K., and Shibuya, M. Significant expression of vascular endothelial growth factor/vascular permeability factor in mouse ascites tumors, Cancer Res., 58: 2652-2660, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 2652-2660
-
-
Luo, J.C.1
Yamaguchi, S.2
Shinkai, A.3
Shitara, K.4
Shibuya, M.5
-
17
-
-
0032542703
-
Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice
-
Yoneda, J., Kuniyasu, H., Crispens, M. A., Price, J. E., Bucana, C. D., and Fidler, I. J. Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice. J. Natl. Cancer Inst. (Bethesda), 90: 447-454, 1998.
-
(1998)
J. Natl. Cancer Inst. (Bethesda)
, vol.90
, pp. 447-454
-
-
Yoneda, J.1
Kuniyasu, H.2
Crispens, M.A.3
Price, J.E.4
Bucana, C.D.5
Fidler, I.J.6
-
18
-
-
0031719516
-
Role of vascular endothelial growth factor in ovarian cancer
-
Mesiano, S., Ferrara, N., and Jaffe, R. B. Role of vascular endothelial growth factor in ovarian cancer. Am. J. Pathol., 153: 1249-1256, 1998.
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 1249-1256
-
-
Mesiano, S.1
Ferrara, N.2
Jaffe, R.B.3
-
19
-
-
0033047875
-
VEGFs, receptors and angiogenesis
-
Veikkola, T., and Alitalo, K. VEGFs, receptors and angiogenesis. Semin. Cancer Biol., 9: 211-220, 1999.
-
(1999)
Semin. Cancer Biol.
, vol.9
, pp. 211-220
-
-
Veikkola, T.1
Alitalo, K.2
-
20
-
-
0032710319
-
Clinical applications of angiogenic growth factors and their inhibitors
-
Ferrara, N., and Alitalo, K. Clinical applications of angiogenic growth factors and their inhibitors. Nat. Med., 5: 1359-1364, 1999.
-
(1999)
Nat. Med.
, vol.5
, pp. 1359-1364
-
-
Ferrara, N.1
Alitalo, K.2
-
21
-
-
0024370274
-
Recent developments in the cell biology of basic fibroblast growth factor
-
Rifkin, D. B., and Moscatelli, D. Recent developments in the cell biology of basic fibroblast growth factor. J. Cell Biol., 109: 1-6, 1989.
-
(1989)
J. Cell Biol.
, vol.109
, pp. 1-6
-
-
Rifkin, D.B.1
Moscatelli, D.2
-
23
-
-
0025913891
-
Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma
-
Kandel, J., Bossy-Wetzel, E., Radvanyi, F., Klagsbrun, M., Folkman, J., and Hanahan, D. Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma. Cell, 66: 1095-1104, 1991.
-
(1991)
Cell
, vol.66
, pp. 1095-1104
-
-
Kandel, J.1
Bossy-Wetzel, E.2
Radvanyi, F.3
Klagsbrun, M.4
Folkman, J.5
Hanahan, D.6
-
24
-
-
0028827625
-
Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
-
Asahara, T., Bauters, C., Zheng, L. P., Takeshita, S., Bunting, S., Ferrara, N., Symes, J. F., and Isner, J. M. Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. Circulation, 92: 365-371, 1995.
-
(1995)
Circulation
, vol.92
, pp. 365-371
-
-
Asahara, T.1
Bauters, C.2
Zheng, L.P.3
Takeshita, S.4
Bunting, S.5
Ferrara, N.6
Symes, J.F.7
Isner, J.M.8
-
25
-
-
0026351399
-
Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner
-
Mignatti, P., Morimoto, T., and Rifkin, D. B. Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner. Proc. Natl. Acad. Sci. USA, 88: 11007-1101, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 11007-11101
-
-
Mignatti, P.1
Morimoto, T.2
Rifkin, D.B.3
-
26
-
-
0027446183
-
Effects of modulation of basic fibroblast growth factor on tumor in vivo
-
Gross, J. L., Herblin, W. F., Dusak, B. A., Czerniak, P., Diamond, M. D., Sun, T., Eidsvoog, K., Dexter, D. L., and Yayon, A. Effects of modulation of basic fibroblast growth factor on tumor in vivo. J. Natl. Cancer Inst. (Bethesda), 85: 121-131, 1993.
-
(1993)
J. Natl. Cancer Inst. (Bethesda)
, vol.85
, pp. 121-131
-
-
Gross, J.L.1
Herblin, W.F.2
Dusak, B.A.3
Czerniak, P.4
Diamond, M.D.5
Sun, T.6
Eidsvoog, K.7
Dexter, D.L.8
Yayon, A.9
-
27
-
-
0008887031
-
Endothelial cell hyperplasia in human glioblastoma: Coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation
-
Hermansson, M., Nister, M., Betsholtz, C., Heldin, C. H., Westermark, B., and Funa, K. Endothelial cell hyperplasia in human glioblastoma: coexpression of mRNA for platelet-derived growth factor (PDGF) B chain and PDGF receptor suggests autocrine growth stimulation. Proc. Natl. Acad. Sci. USA, 85: 7748-7752. 1988.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 7748-7752
-
-
Hermansson, M.1
Nister, M.2
Betsholtz, C.3
Heldin, C.H.4
Westermark, B.5
Funa, K.6
-
28
-
-
0026439870
-
Platelet-derived growth factor receptor β is induced during tumor development and upregulated during tumor progression in endothelial cells in human gliomas
-
Plate, K. H., Breier, G., Farrell, C. L., and Risau, W. Platelet-derived growth factor receptor β is induced during tumor development and upregulated during tumor progression in endothelial cells in human gliomas. Lab Investig., 67: 529-534, 1992.
-
(1992)
Lab Investig.
, vol.67
, pp. 529-534
-
-
Plate, K.H.1
Breier, G.2
Farrell, C.L.3
Risau, W.4
-
29
-
-
0030756325
-
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
-
Lindahl, P., Johansson, B. R., Leveen, P., and Betsholtz, C. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science (Wash. DC), 277: 242-245, 1997.
-
(1997)
Science (Wash. DC)
, vol.277
, pp. 242-245
-
-
Lindahl, P.1
Johansson, B.R.2
Leveen, P.3
Betsholtz, C.4
-
30
-
-
0023815412
-
Expression of platelet-derived growth factor (PDGF)-related transcripts and synthesis of biologically active PDGF-like proteins by human malignant epithelial cell lines
-
Sariban, E., Sitaras, N. M., Antoniades, H. N., Kufe, D. W., and Pantazis, P. Expression of platelet-derived growth factor (PDGF)-related transcripts and synthesis of biologically active PDGF-like proteins by human malignant epithelial cell lines. J. Clin. Investig., 82: 1157-1164, 1988.
-
(1988)
J. Clin. Investig.
, vol.82
, pp. 1157-1164
-
-
Sariban, E.1
Sitaras, N.M.2
Antoniades, H.N.3
Kufe, D.W.4
Pantazis, P.5
-
31
-
-
0027365546
-
Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasm
-
Henriksen, R., Funa, K., Wilander, E., Backstrom, T., Ridderheim, M., and Oberg, K. Expression and prognostic significance of platelet-derived growth factor and its receptors in epithelial ovarian neoplasm. Cancer Res., 53: 4550-4554, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4550-4554
-
-
Henriksen, R.1
Funa, K.2
Wilander, E.3
Backstrom, T.4
Ridderheim, M.5
Oberg, K.6
-
32
-
-
0030866653
-
Expression of basic fibroblast growth factor and its mRNA in advanced ovarian cancers
-
Fujimoto, J., Ichigo, S., Hori, M., Hirose, R., Sakaguchi, H., and Tamaja, T. Expression of basic fibroblast growth factor and its mRNA in advanced ovarian cancers. Eur. J. Gynaecol. Oncol., 18: 349-352, 1997.
-
(1997)
Eur. J. Gynaecol. Oncol.
, vol.18
, pp. 349-352
-
-
Fujimoto, J.1
Ichigo, S.2
Hori, M.3
Hirose, R.4
Sakaguchi, H.5
Tamaja, T.6
-
33
-
-
0033650988
-
New paradigms for the treatment of cancer: The role of anti-angiogenesis agents
-
Cherrington, J. M., Strawn, L. M., and Shawver. L. K. New paradigms for the treatment of cancer: the role of anti-angiogenesis agents. Adv. Cancer Res., 79: 1-38, 2000.
-
(2000)
Adv. Cancer Res.
, vol.79
, pp. 1-38
-
-
Cherrington, J.M.1
Strawn, L.M.2
Shawver, L.K.3
-
34
-
-
0033883776
-
SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors
-
Laird, A. D., Vajkoczy, P., Shawver, L. K., Thurnher, A., Liang, C., Mohammadi, M., Schlessinger, J., Ullrich, A., Hubbard, S. R., Blake, R. A., Fong, T. A. T., Strawn, L. M., Sun, L., Tang, C., Hawtin, R., Tang, F., Shenoy, N., Hirth, K. P., McMahon, G., and Cherrington, J. M. SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors. Cancer Res., 60: 4152-4160, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 4152-4160
-
-
Laird, A.D.1
Vajkoczy, P.2
Shawver, L.K.3
Thurnher, A.4
Liang, C.5
Mohammadi, M.6
Schlessinger, J.7
Ullrich, A.8
Hubbard, S.R.9
Blake, R.A.10
Fong, T.A.T.11
Strawn, L.M.12
Sun, L.13
Tang, C.14
Hawtin, R.15
Tang, F.16
Shenoy, N.17
Hirth, K.P.18
McMahon, G.19
Cherrington, J.M.20
more..
-
35
-
-
0035866334
-
Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms
-
Shaheen, R. M., Tseng, W. W., Davis, D. V., Liu, W., Reinmuth, N., Vellagas, R., Wieczorek, A. A., Ogura, Y., McConkey, D. J., Drazan, K. E., Bucana, C. D., McMahon, G., and Ellis, L. M. Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms. Cancer Res., 61: 1464-1468, 2001.
-
(2001)
Cancer Res.
, vol.61
, pp. 1464-1468
-
-
Shaheen, R.M.1
Tseng, W.W.2
Davis, D.V.3
Liu, W.4
Reinmuth, N.5
Vellagas, R.6
Wieczorek, A.A.7
Ogura, Y.8
McConkey, D.J.9
Drazan, K.E.10
Bucana, C.D.11
McMahon, G.12
Ellis, L.M.13
-
36
-
-
0024435434
-
Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapy
-
Masazza, G., Tomasoni, A., Lucchini, V., Allavena, P., Erba, E., Colombo, N., Mantovani, A., D'Incalci, M., Mangioni, C., and Giavazzi, R. Intraperitoneal and subcutaneous xenografts of human ovarian carcinoma in nude mice and their potential in experimental therapy. Int. J. Cancer, 44: 494-500, 1989.
-
(1989)
Int. J. Cancer
, vol.44
, pp. 494-500
-
-
Masazza, G.1
Tomasoni, A.2
Lucchini, V.3
Allavena, P.4
Erba, E.5
Colombo, N.6
Mantovani, A.7
D'Incalci, M.8
Mangioni, C.9
Giavazzi, R.10
-
37
-
-
0032145522
-
Molecular characterisation of a panel of human ovarian carcinoma xenografts
-
Codegoni, A. M., Nicoletti, M. I., Buraggi, G., Valoti, G., Giavazzi, R., D'Incalci, M., Landoni, F., Maneo, A., and Broggini, M. Molecular characterisation of a panel of human ovarian carcinoma xenografts. Eur. J. Cancer, 9: 1432-1438, 1998.
-
(1998)
Eur. J. Cancer
, vol.9
, pp. 1432-1438
-
-
Codegoni, A.M.1
Nicoletti, M.I.2
Buraggi, G.3
Valoti, G.4
Giavazzi, R.5
D'Incalci, M.6
Landoni, F.7
Maneo, A.8
Broggini, M.9
-
38
-
-
0029657597
-
Paclitaxel (Taxol) inhibits motility of paclitaxel-resistant human ovarian carcinoma cells
-
Belotti, D., Rieppi, M., Nicoletti, M. I., Casazza, A. M., Fojo, T., Taraboletti, G., and Giavazzi, R. Paclitaxel (Taxol) inhibits motility of paclitaxel-resistant human ovarian carcinoma cells. Clin. Cancer Res., 2: 1725-1730, 1996.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1725-1730
-
-
Belotti, D.1
Rieppi, M.2
Nicoletti, M.I.3
Casazza, A.M.4
Fojo, T.5
Taraboletti, G.6
Giavazzi, R.7
-
39
-
-
0028046061
-
Soluble intercellular adhesion molecule-1 (ICAM-1) is released into the serum and ascites of human ovarian carcinoma patients and in nude mice bearing tumour xenografts
-
Giavazzi, R., Nicoletti, M. I., Chirivi, R. G. S., Hemingway, I., Bernasconi, S., Allavena, P., and Gearing, A. J. H. Soluble intercellular adhesion molecule-1 (ICAM-1) is released into the serum and ascites of human ovarian carcinoma patients and in nude mice bearing tumour xenografts. Eur. J. Cancer, 30: 1865-1870, 1994.
-
(1994)
Eur. J. Cancer
, vol.30
, pp. 1865-1870
-
-
Giavazzi, R.1
Nicoletti, M.I.2
Chirivi, R.G.S.3
Hemingway, I.4
Bernasconi, S.5
Allavena, P.6
Gearing, A.J.H.7
-
40
-
-
0033986112
-
Anticancer drug targets: Growth factors and growth factor signaling
-
Gibbs, J. B. Anticancer drug targets: growth factors and growth factor signaling. J. Clin. Investig., 105: 9-13, 2000.
-
(2000)
J. Clin. Investig.
, vol.105
, pp. 9-13
-
-
Gibbs, J.B.1
-
41
-
-
85017325712
-
Tyrosine kinases in disease: Overview of kinase inhibitors as therapeutic agents and current drugs in clinical trials
-
Strawn, L. M., and Shawver, L. K. Tyrosine kinases in disease: overview of kinase inhibitors as therapeutic agents and current drugs in clinical trials. Exp. Opin. Investig. Drugs, 7: 553-573, 1998.
-
(1998)
Exp. Opin. Investig. Drugs
, vol.7
, pp. 553-573
-
-
Strawn, L.M.1
Shawver, L.K.2
-
42
-
-
0034655182
-
PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
-
Wood, J. M., Bold, G., Buchdunger, E., Cozens, R., Ferrari, S., Frei, J., Hofmann, F., Mestan, J., Mett, H., O'Reilly, T., Persohn, E., Rosel, J., Schnell, C., Stover, D., Theuer, A., Towbin, H., Wenger, F., Woods-Cook, K., Menrad, A., Siemeister, G., Schirner, M., Thierauch, K., Schneider, M. R., Drevs, J., Martiny-Baron, G., Totzke, F., and Marmé, D. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res., 60: 2178-2189, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 2178-2189
-
-
Wood, J.M.1
Bold, G.2
Buchdunger, E.3
Cozens, R.4
Ferrari, S.5
Frei, J.6
Hofmann, F.7
Mestan, J.8
Mett, H.9
O'Reilly, T.10
Persohn, E.11
Rosel, J.12
Schnell, C.13
Stover, D.14
Theuer, A.15
Towbin, H.16
Wenger, F.17
Woods-Cook, K.18
Menrad, A.19
Siemeister, G.20
Schirner, M.21
Thierauch, K.22
Schneider, M.R.23
Drevs, J.24
Martiny-Baron, G.25
Totzke, F.26
Marmé, D.27
more..
-
43
-
-
12244277954
-
Development of SU5416, a selective small molecule inhibitor of VEGF receptor tyrosine kinase activity, as an anti-angiogenesis agent
-
Mendel, D. B., Laird, A. D., Smolich, B. D., Blake, R. A., Liang, C., Hannah, A. L., Shaheen, R. M., Ellis, L. M., Weitman, S., Shawver, L. K., and Cherrington, J. M. Development of SU5416, a selective small molecule inhibitor of VEGF receptor tyrosine kinase activity, as an anti-angiogenesis agent. Anticancer Drug Des., 15: 29-41, 2000.
-
(2000)
Anticancer Drug Des.
, vol.15
, pp. 29-41
-
-
Mendel, D.B.1
Laird, A.D.2
Smolich, B.D.3
Blake, R.A.4
Liang, C.5
Hannah, A.L.6
Shaheen, R.M.7
Ellis, L.M.8
Weitman, S.9
Shawver, L.K.10
Cherrington, J.M.11
-
44
-
-
0034145605
-
Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases
-
Xu, L., Yoneda, J., Herrera, C., Wood, J., Killion, J. J., and Fidler, I. J. Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Int. J. Oncol., 16: 445-454, 2000.
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 445-454
-
-
Xu, L.1
Yoneda, J.2
Herrera, C.3
Wood, J.4
Killion, J.J.5
Fidler, I.J.6
-
45
-
-
0034212763
-
Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma
-
Bruns, C. J., Solorzano, C. C., Harbison, M. T., Ozawa, S., Tsan, R., Fan, D., Abbruzzese, J., Traxler, P., Buchdunger, E., Radinsky, R., and Fidler, I. J. Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma. Cancer Res., 60: 2926-2935, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 2926-2935
-
-
Bruns, C.J.1
Solorzano, C.C.2
Harbison, M.T.3
Ozawa, S.4
Tsan, R.5
Fan, D.6
Abbruzzese, J.7
Traxler, P.8
Buchdunger, E.9
Radinsky, R.10
Fidler, I.J.11
-
46
-
-
0029802685
-
The microtubule-affecting drug paclitaxel has antiangiogenic activity
-
Belotti, D., Vergani, V., Drudis, T., Borsotti, P., Pitelli, M. R., Viale, G., Giavazzi, R., and Taraboletti, G. The microtubule-affecting drug paclitaxel has antiangiogenic activity. Clin. Cancer Res., 2: 1843-1849, 1996.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 1843-1849
-
-
Belotti, D.1
Vergani, V.2
Drudis, T.3
Borsotti, P.4
Pitelli, M.R.5
Viale, G.6
Giavazzi, R.7
Taraboletti, G.8
-
47
-
-
0035347301
-
Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival
-
Reinmuth, N., Liu, W., Jung, Y. D., Ahmad, S. A., Shaheen, R. M., Fan, F., Bucana, C. D., McMahon, G., Gallick, G. E., and Ellis, L. M. Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival. FASEB J., 15: 1239-1241, 2001.
-
(2001)
FASEB J.
, vol.15
, pp. 1239-1241
-
-
Reinmuth, N.1
Liu, W.2
Jung, Y.D.3
Ahmad, S.A.4
Shaheen, R.M.5
Fan, F.6
Bucana, C.D.7
McMahon, G.8
Gallick, G.E.9
Ellis, L.M.10
-
48
-
-
0036242810
-
SU6668 inhibits Flk-1/KDR and PDGFRβ in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice
-
Laird, A. D., Christensen, J. G., Li, G., Carver, J., Smith, K., Xin, X., Moss, K. G., Louie, S. G., Mendel, D. B., and Cherrington, J. M. SU6668 inhibits Flk-1/KDR and PDGFRβ in vivo, resulting in rapid apoptosis of tumor vasculature and tumor regression in mice. FASEB J., 16: 681-690, 2002.
-
(2002)
FASEB J.
, vol.16
, pp. 681-690
-
-
Laird, A.D.1
Christensen, J.G.2
Li, G.3
Carver, J.4
Smith, K.5
Xin, X.6
Moss, K.G.7
Louie, S.G.8
Mendel, D.B.9
Cherrington, J.M.10
-
49
-
-
0028834106
-
Pathogenesis of ascites tumor growth: Vascular permeability factor, vascular hyperpermeability, and ascites fluid accumulation
-
Nagy, J. A., Masse, E. M., Herzberg, K. T., Meyers, M. S., Yeo, K. T., Yeo, T. K., Sioussat, T. M., and Dvorak, H. F. Pathogenesis of ascites tumor growth: vascular permeability factor, vascular hyperpermeability, and ascites fluid accumulation. Cancer Res., 55: 360-368, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 360-368
-
-
Nagy, J.A.1
Masse, E.M.2
Herzberg, K.T.3
Meyers, M.S.4
Yeo, K.T.5
Yeo, T.K.6
Sioussat, T.M.7
Dvorak, H.F.8
-
50
-
-
0347377779
-
Differential inhibition of fluid accumulation and tumor growth in two mouse ascites tumors by an antivascular endothelial growth factor/permeability factor neutralizing antibody
-
Luo, J. C., Toyoda, M., and Shibuya, M. Differential inhibition of fluid accumulation and tumor growth in two mouse ascites tumors by an antivascular endothelial growth factor/permeability factor neutralizing antibody. Cancer Res., 58: 2594-2600, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 2594-2600
-
-
Luo, J.C.1
Toyoda, M.2
Shibuya, M.3
-
51
-
-
0037390017
-
Is one promiscuous drug against multiple targets better than combinations of molecule-specific drug?
-
Arteaga, C. L. Is one promiscuous drug against multiple targets better than combinations of molecule-specific drug? Clin. Cancer Res., 9: 1231-1232, 2003.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 1231-1232
-
-
Arteaga, C.L.1
-
52
-
-
0031952212
-
Paclitaxel/carboplatin administration along with antiangiogenic, therapy in non-small-cell lung and breast carcinoma models
-
Herbst, R. S., Takeuchi, H., and Teicher, B. A. Paclitaxel/carboplatin administration along with antiangiogenic, therapy in non-small-cell lung and breast carcinoma models. Cancer Chemother. Pharmacol., 41: 497-504, 1998.
-
(1998)
Cancer Chemother. Pharmacol.
, vol.41
, pp. 497-504
-
-
Herbst, R.S.1
Takeuchi, H.2
Teicher, B.A.3
-
53
-
-
0036790060
-
Inhibition of PDGF receptor signaling in stroma enanches antitumor effect of chemotherapy
-
Pietras, K., Rubin, K., Sjoblom, T., Buchdunger, E., Sjoquist, M., Heldin, C., and Ostman, A. Inhibition of PDGF receptor signaling in stroma enanches antitumor effect of chemotherapy. Cancer Res., 62: 5476-5484, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 5476-5484
-
-
Pietras, K.1
Rubin, K.2
Sjoblom, T.3
Buchdunger, E.4
Sjoquist, M.5
Heldin, C.6
Ostman, A.7
-
54
-
-
0035865363
-
Redefining the target: Chemotherapeutics as antiangiogenics
-
Miller, K. D., Sweeney, C. J., and Sledge, G. W. Redefining the target: chemotherapeutics as antiangiogenics. J. Clin. Oncol., 19: 1195-1206, 2001.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 1195-1206
-
-
Miller, K.D.1
Sweeney, C.J.2
Sledge, G.W.3
-
55
-
-
0034534249
-
Antiangiogenic chemotherapeutic agents
-
Schirner, M., Antiangiogenic chemotherapeutic agents. Cancer Metastasis Rev., 19: 67-73, 2000.
-
(2000)
Cancer Metastasis Rev.
, vol.19
, pp. 67-73
-
-
Schirner, M.1
-
56
-
-
0034048358
-
Less is more, regularly: Metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
-
Hanahan, D., Bergers, G., and Bergsland, E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J. Clin. Investig., 105: 1045-1047, 2000.
-
(2000)
J. Clin. Investig.
, vol.105
, pp. 1045-1047
-
-
Hanahan, D.1
Bergers, G.2
Bergsland, E.3
-
57
-
-
0034087691
-
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained regression without over toxicity
-
Klement, G., Baruchel, S., Rak, J., Man, S., Clark, K., Hicklin, D. J., Bohlen, P., and Kerbel, R. S. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained regression without over toxicity. J. Clin. Investig., 105: 15-24, 2000.
-
(2000)
J. Clin. Investig.
, vol.105
, pp. 15-24
-
-
Klement, G.1
Baruchel, S.2
Rak, J.3
Man, S.4
Clark, K.5
Hicklin, D.J.6
Bohlen, P.7
Kerbel, R.S.8
-
58
-
-
0034032882
-
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
-
Browder, T., Butterfield, C. E., Kraling, B. M., Shi, B., Marshall, B., O'Reilly, M. S., and Folkman, J. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res., 60: 1878-1886, 2000.
-
(2000)
Cancer Res.
, vol.60
, pp. 1878-1886
-
-
Browder, T.1
Butterfield, C.E.2
Kraling, B.M.3
Shi, B.4
Marshall, B.5
O'Reilly, M.S.6
Folkman, J.7
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