Hemoglobin and the paracrine and endocrine functions of nitric oxide

New England Journal of Medicine

Volumn 348, Issue 15, 2003, Pages 1483-1485

  Schechter, Alan N ^a   Gladwin, Mark T ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; NITRIC OXIDE; OXYHEMOGLOBIN; S NITROSOHEMOGLOBIN; UNCLASSIFIED DRUG;

ARTICLE; CARDIOVASCULAR SYSTEM; ENDOCRINE FUNCTION; HUMAN; MOLECULAR INTERACTION; NONHUMAN; OXYGEN TENSION; PARACRINE SIGNALING; PRIORITY JOURNAL; VASODILATATION;

ENDOCRINE SYSTEM; ERYTHROCYTES; HEMOGLOBINS; HUMANS; NITRIC OXIDE; PARACRINE COMMUNICATION; RESPIRATORY PHYSIOLOGY;

EID: 0037430993     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMcibr023045     Document Type: Article

References (6)

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2. McMahon TJ, Moon RE, Luschinger BP, et al. Nitric oxide in the human respiratory cycle. Nat Med 2002;8:711-7.
3. Joshi MS, Ferguson TB Jr, Han TH, et al. Nitric oxide is consumed, rather than conserved, by reaction with oxyhemoglobin under physiological conditions. Proc Natl Acad Sci U S A 2002;99:10341-6.
4. 2/NO-linked allosteric function. J Biol Chem 2002;277:27818-28.
5. Rassaf T, Preik M, Kleinbongard P, et al. Evidence for in vivo transport of bioactive nitric oxide in human plasma. J Clin Invest 2002;109:1241-8.
6. Reiter CD, Wang X, Tanus-Santos JE, et al. Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease. Nat Med 2002;8:1383-9.