2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: An exploration of the role of the pyrrolic scaffold

Farmaco

Volumn 58, Issue 10, 2003, Pages 1005-1009

  Micheli, Fabrizio ^a   Di Fabio, Romano ^a   Cavanni, Paolo ^a   Donati, Daniele ^a   Faedo, Stefania ^a   Gehanne, Sylvie ^a   Maffeis, Micaela ^a   Marchioro, Carla ^a   Sabbatini, Fabio Maria ^a   Tarzia, Giorgio ^a   Tranquillini, Maria Elvira ^a   Viziano, Monica ^a,b  

^a GSK   (Italy)

^b GILEAD SCIENCES   (United States)

Author keywords

2,4 Dicarboxy pyrroles; Antagonists; Pyrrole scaffold

Indexed keywords

3 (1,2,2 TRIMETHYLPROPYL) 4 (3,5 DIMETHYL 2 PROPYLOXYCARBONYL)PYRROLECARBOXYLATE; GLUTAMATE RECEPTOR ANTAGONIST; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; NONHUMAN;

EID: 10744220113     PISSN: 0014827X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-827X(03)00112-5     Document Type: Article

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