Synthesis of a library of benzoindolizines using poly(ethylene glycol) as soluble support

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 2, 2005, Pages 453-458

  Yue, Guizhou ^a   Wan, Yadong ^a   Song, Shaojun ^a   Yang, Guichun ^a   Chen, Zuxing ^a  

^a HUBEI UNIVERSITY   (China)

Author keywords

Benzoindolizine; Poly(ethylene glycol); Polymer supported; Ylide

Indexed keywords

ALKENE DERIVATIVE; ALKYNE DERIVATIVE; CHROMIC ACID; INDOLIZINE DERIVATIVE; ISOQUINOLINE DERIVATIVE; MACROGOL; POLYMER; QUINOLINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

BENZENE; INDOLIZINES; ISOQUINOLINES; MODELS, CHEMICAL; POLYETHYLENE GLYCOLS; QUINOLINES; SOLUBILITY;

EID: 10644294597     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.10.054     Document Type: Article

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38. n-)
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40. 3: C, 69.12; H, 5.39; N, 5.76. Found: C, 69.10; H, 5.35; N, 5.77
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42. n-)
43. 3): δ = 9.41 (d, 1H, J = 7.8 Hz, Ar-H), 7.95 (d, 1H, J = 8.4 Hz, Ar-H), 7.74 (d, 2H, J = 7.2 Hz, Ar-H), 7.70 (d, 1H, J = 9.0 Hz, Ar-H), 7.48(t, 1H, J = 7.5 Hz, Ar-H), 7.41 (t, 1H, J = 7.2 Hz, Ar-H), 7.34 (t, 1H, J = 7.8 Hz, Ar-H), 7.26-7.13 (m, 8H, Ar-H), 3.67 (s, 3H, COOMe).