Mutations in the DNA-binding domain of the transcription factor bright act as dominant negative proteins and interfere with immunoglobulin transactivation

Journal of Biological Chemistry

Volumn 279, Issue 50, 2004, Pages 52465-52472

  Nixon, Jamee C ^a,b   Rajaiya, Jaya ^a   Webb, Carol F ^a,b  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DIMERS; ENZYMES; MUTAGENESIS;

CELL REGULATORS; CHAIN TRANSCRIPTION; INTRONIC ENHANCERS; MUTATIONS;

DNA;

IMMUNOGLOBULIN HEAVY CHAIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BRIGHT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CHO CELL; CONTROLLED STUDY; DNA BINDING; DNA FLANKING REGION; GENE MUTATION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; TRANSACTIVATION; UPREGULATION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CHO CELLS; CRICETINAE; DIMERIZATION; DNA; DNA-BINDING PROTEINS; IMMUNOGLOBULIN MU-CHAINS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; ONCOGENES; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSFECTION;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; MURINAE;

EID: 10644294544     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M403028200     Document Type: Article

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