The spectrum of pediatric fibroblastic and myofibroblastic tumors

Ultrastructural Pathology

Volumn 28, Issue 5-6, 2004, Pages 265-281

  Hicks, John ^a   Mierau, Gary ^b  

^a TEXAS CHILDREN S HOSPITAL   (United States)

^b CHILDREN S HOSPITAL   (United States)

Author keywords

Digital fibromatosis; Electron microscopy; Fibroblast; Fibrodysplasia ossificans progressive; Fibrous hamartoma; Hyaline fibromatosis; Immunocytochemistry; Inclusion body fibromatosis; Infantile fibrosarcoma; Myofibroblast; Myofibroma

Indexed keywords

CALCIFYING APONEUROTIC FIBROMA; CALCIFYING FIBROUS TUMOR; CANCER DIAGNOSIS; CANCER GENETICS; CELL ULTRASTRUCTURE; CHILDHOOD CANCER; CONFERENCE PAPER; CYTOGENETICS; DESMOID TUMOR; DIAGNOSTIC ACCURACY; EMERGENCY HEALTH SERVICE; FASCIITIS; FIBROMA; FIBROMATOSIS; FOLLOW UP; GARDNER SYNDROME; HEMANGIOPERICYTOMA; HUMAN; IMMUNOCYTOCHEMISTRY; INCLUSION BODY FIBROMATOSIS; INFANTILE FIBROSARCOMA; INFANTILE HEMANGIOPERICYTOMA; LEIOMYOMA; LIPOFIBROMA; MORPHOLOGY; OSSIFYING MYOSITIS; PLASMA CELL GRANULOMA; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; FIBROBLASTS; FIBROMA; HUMANS; INFANT; INFANT, NEWBORN; MICROSCOPY, ELECTRON, TRANSMISSION; MYOFIBROMA; NEOPLASMS, FIBROUS TISSUE; NEOPLASMS, MUSCLE TISSUE;

EID: 10644285599     PISSN: 01913123     EISSN: None     Source Type: Journal    
DOI: 10.1080/019131290882105     Document Type: Conference Paper

References (46)

1. Coffin CM, Dehner LP. Fibroblastic-myofibroblastic tumors in children and adolescents: a clinicopathologic study of 108 examples in 103 patients. Pediatr Pathol. 1991;11:569-588.
2. Coffin CM, Dehner LP. Soft tissue tumors in first year of life: a report of 190 cases. Pediatr Pathol. 1990;10:509-526.
3. Coffin CM, Dehner LP. Pathologic evaluation of pediatric soft tissue tumors. Am J Clin Pathol. 1998;109(4 Suppl 1):S38-S52.
4. Fletcher CDM, Unni KK, Mertens F. Fibroblastic/myofibroblastic tumors, In: Fletcher CDM, Unni KK, Mertens F, eds. Tumours of Soft Tissue and Bone. Lyon, France: IARC Press, 2002:47-108.
5. Coffin CM, Jaszcz W, O'Shea PA, Dehner LP. So-called congenital-infantile fibrosarcoma: does it exist and what is it? Pediatr Pathol. 1994;14:133-150.
6. Sandberg AA, Bridge JA. Updates on the cytogenetics and molecular genetics of bone and soft tissue tumor: congenital (infantile) fibrosarcoma and mesoblastic nephroma. Cancer Genet Cytogenet. 2002;132:1-13.
7. Wherli BM, Weiss SW, Yandow S, Coffin CM. Gardner-associated fibromas (GAF) in young patients: a distinct fibrous lesion that identifies unsuspected Gardner syndrome and risk for fibromatosis. Am J Surg Pathol. 2001;25:645-651.
8. Joshi VJ, Balarezo F, Hicks MJ, Mierau GW, Tsongalis GJ. Approach to small round cell tumors of childhood. Pathol Case Rev. 2000;5:26-41.
9. Trobs RB, Meier R, Bennek J, Heinrich S, Willnow U. Fibrosarcoma in infants and children: a retrospective analysis-overdiagnosis in early years. Pediatr Surg Int. 1999;15:123-128.
10. Cecchetto G, Carli M, Alaggio R, et al. Italian Cooperative Group. Fibrosarcoma in pediatric patients: results of the Italian Cooperative Group studies (1975-1995). J Surg Oncol. 2001;78:225-231.
11. O, Malley DP, Mierau GW, Beckwith JB, Weeks DA. Ultrastructure of cellular mesoblastic nephroma. Ultrastruct Pathol. 1996;20:417-427.
12. Loeb DM, Hill DA, Dome JS. Complete response of recurrent cellular congenital mesoblastic nephroma to chemotherapy. J Pediatr Hematol Oncol. 2002;24:478-481.
13. Shetty AK, Yu LC, Gardner RV, Warner RP. Role of chemotherapy in the treatment of infantile fibrosarcoma. Med Pediatr Oncol. 1999;33:425-427.
14. Loh ML, Ahn P, Perez-Atayde AR, Gebhardt MC, Shamberger RC, Grier HE. Treatment of infantile fibrosarcoma with chemotherapy and surgery: results from the Dana-Farber Cancer Institute and Children's Hospital, Boston. J Pediatr Hematol Oncol. 2002;24:722-726.
15. McCahon E, Sorensen PHB, Davis JH, Rogers PCJ, Schultz KR. Non-resectable congenital tumors with the ETV6-NTRK3 gene fusion are highly responsive to chemotherapy. Med Pediatr Oncol. 2003;40:288-292.
16. Adem C, Gisselsson D, Cin PD, Nascimento AG. ETV6 rearrangements in patients with infantile fibrosarcomas and congenital mesoblastic nephromas by fluorescence in situ hybridization. Mod Pathol. 2001;14:1246-1251.
17. Argani P, Fritsch M, Kadkol SS, Schuster A, Beckwith JB, Perlman EJ. Detection of ETV6-NTRK3 chimeric RNA of infantile fibrosarcoma/cellular congenital mesoblastic nephroma in paraffin-embedded tissue: application to challenging pediatric renal stromal tumors. Mod Pathol. 1999;13:29-36.
18. Bourgeois JM, Knezevich SR, Mathers JA, Sorensen PHB. Molecular detection of the ETV6-NTRK3 gene fusion differentiates congenital fibrosarcoma form other childhood spindle cell tumors. Am J Surg Pathol. 2000;24:937-946.
19. Knezevich SR, McFadden DE, Tao W, Lim JF, Sorensen PH: A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. Nat Genet. 1998;18:184-187.
20. Behar PM, Albritton FD, Muller S, Todd NW. Multicentric infantile myofibromatosis. Int J Pediatr Otorhinolarngol. 1998;45:249-254.
21. Netscher DT, Eladoumikdachi F, Popek, EJ. Infantile myofibromatosis; case report of a solitary hand lesion with emphasis on differential diagnosis and management. Ann Plast Surg. 2001;46:62-67.
22. Ikediobi NI, Iyengar V, Hwang L, Collins WE, Metry DW. Infantile myofibromatosis: support for autosomal dominant inheritance. J Am Acad Dermatol. 2003;49:S148-S150.
23. Mentzel T, Calonje E, Nascimento AG, Fletcher CDM. Infantile hemangiopericytoma versus infantile myofibromatosis: study of a series suggesting a continuous spectrum of infantile myofibroblastic lesions. Am J Surg Pathol. 1994;18:922-930.
24. Variend S, Bax NMA, Van Gorp J. Are infantile myofibromatosis, congenital fibrosarcoma and congenital haemangiopericytoma histogenetically related? Histopathology. 1995;26:57-62.
25. Dahlen A, Fletcher CDM, Mertens F, et al. Activation of the GLI oncogene through fusion with the beta-actin (ACTB) gene in a group of pericytic tumor with t(7; 12): pericytoma with (t7;12). Am J Pathol. 2004;164:1645-1653.
26. Falcon NA, Upton J. Infantile digital fibromas. J Hand Surg. 1995;20A:1014-1020.
27. Rimareix F, Bardot J, Andrac L, Vasse D, Galinier P, Magalon G. Infantile digital fibroma: report of eleven cases. Eur J Pediatr Surg. 1997;7:345-348.
28. Horii E, Sugiura Y, Nakamura R. A syndrome of digital fibromas, facial pigmentary dysplasia, and metacarpal and metatarsal disorganization. Am J Med Gen. 1998;80:1-5.
29. Breuning MH, Oranje AP, Langemeijer RA, et al. Recurrent digital fibroma, focal dermal hypoplasia, and limb malformations. Am J Med Gen. 2000;94:91-101.
30. Dickey GE, Sotelo-Avila C. Fibrous hamartoma of infancy: current review. Pediatr Dev Pathol. 1999;2:236-243.
31. Scott DM, Pena JR, Omura EF. Fibrous hamartoma of infancy. J Am Acad Dermatol. 1999;41(5 Pt2):857-859.
32. Halem A, Al-Hindi HN, Al-Juboury M, Al-Husseini H, Al-Ajlan A. Juvenile hyaline fibromatosis: morphologic, immunohistochemical, and ultrastructural study of three siblings. Am J Dermatopathol. 2002;24:218-224.
33. Breier F, Fang-Kircher S, Wolff K, Jurecka W. Juvenile hyaline fibromatosis: impaired collagen metabolism in human skin fibroblasts. Arch Dis Child. 1997;77:436-440.
34. Rahman N, Dunstan M, Teare MD, et al. The gene for juvenile hyaline fibromatosis maps to chromosome 4p21. Am J Hum Genet. 2002;71:975-980.
35. Hanks S, Adams S, Douglas J, et al. Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyalinosis fibromatosis and infantile systemic hyalinosis. Am J Hum Genet. 2003;73:791-800.
36. Dowling O, Difeo A, Ramirez MC, et al. Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am J Hum Genet. 2003;73:957-966.
37. Feldman G, Li Ming, Martin S, et al. Fibrodysplasia ossficans progressiva, a heritable disorder of severe heterotopic ossification, maps to human chromosome 4p27-31. Am J Hum Genet. 2000;66:128-135.
38. Kaplan FS, Glaser DL, Hebela N, Shore EM. Heterotopic ossification. J Am Acad Orthop Surg. 2004;12:116-125.
39. Blaszczyk M, Majewski S, Brzezinska-Weislo L, Jablonska S. Fibrodysplasia ossificans progressiva. Eur J Dermatol. 2003;13:234-237.
40. Brandao-Paim L, de Lourdes-Liphaus B, da Silva CAA. Fibrodysplasia ossificans progressiva. Indian Pediatr. 2003;40:786-788.
41. Gannon GH, Glaser DL, Caron R, Thompson LD, Shore EM, Kaplan FS. Mast cell involvement in fibrodysplasia ossificans progressiva. Hum Pathol. 2001;32:842-848.
42. Olmsted EA, Kaplan FS, Shore EM. Bone morphogenic protein-4 regulation in fibrodysplasia ossificans progressiva. Clin Orthop. 2003;408:331-343.
43. Hegyi L, Cannon FH, Glaser DL, Shore EM, Kaplan FS, Shanahan CM. Stromal cells of fibrodysplasia ossificans progressive lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa-1: clues to a vascular origin of heterotopic ossification? J Pathol. 2003;201:141-148.
44. Lucotte G, Barthelier C, Mercier G, et al. Localization of the gene for fibrodysplasia ossificans progressive (FOP) to chromosome 17q21-22. Genet Couns. 2000;11:329-334.
45. Glaser DL, Economides AN, Wang L, et al. In vivo somatic cell gene transfer of an engineered Noggin mutein protein prevents BMP4-induced heterotopic ossification. J Bone Joint Surg Am. 2003;85-A:2332-2342.
46. Semonin O, Fontaine K, Daviaud C, Ayuso C, Lucotte G. Identification of three novel mutations of the noggin gene in patients with fibrodysplasia ossificans progressive. Am J Med Genet. 2001;102:314-317.