Localization of the gene for fibrodysplasia ossificans progressiva (FOP) to chromosome 17q21-22

Genetic Counseling

Volumn 11, Issue 4, 2000, Pages 329-334

  Lucotte, G ^a   Bathelier, C ^a   Mercier, G ^a   Gerard, N ^a   Lenoir, G ^a   Semonin, O ^a   Fontaine, K ^a  

^a HÔPITAL MAISON BLANCHE   (France)

Author keywords

Candidate gene; Fibrodysplasia ossificans progressiva (FOP); Genomewide linkage analysis; Localization in 17q21 22; Noggin (NOG)

Indexed keywords

ARTICLE; CHROMOSOME 17Q; GENE LOCATION; GENETIC ANALYSIS; GENETIC HETEROGENEITY; GENETIC LINKAGE; HUMAN; OSSIFYING MYOSITIS; PHENOTYPE; TOE MALFORMATION;

CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 17; FEMALE; GENOTYPE; HUMANS; LINKAGE (GENETICS); MALE; MICROSATELLITE REPEATS; MYOSITIS OSSIFICANS; PEDIGREE;

EID: 0034535415     PISSN: 10158146     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton
2. The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva
3. Genetic aspects of fibrodysplasia ossificans progressiva
4. A three generation family with fibrodysplasia ossificans progressiva
5. Fibromatose et fibrodysplasie ossifiante progressive: Une erreur diagnostique evitable
6. A comprehensive genetic map of the human genome based on 5 264 microsatellites
7. Fibrodysplasia ossificans progressiva, a heritable disorder of severe heterotopic ossification, maps to human chromosome 4q27-31
8. Genetic transmission of fibrodysplasia ossificans progressiva
9. Parametric and nonparametric linkage analysis: A unified multipoint approach
10. Easy calculations or lod scores and genetic risks on small computers
11. A de novo heterozygous deletion of 42 base-pairs in the nog gin gene or a fibrodysplasia ossificans progressiva patient
12. Does noggin head a new class or Kunitz domain?
13. Bone morphogenetic proteins: An update on basic biology and clinical relevance
14. Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva
15. The human bone morphogenetic protein 4 gene: Molecular structure and transcriptional regulation
16. Fibrodysplasia (myositis) ossificans progressiva: Clinicopathological features and natural history
17. Identification of mammalian noggin and its expression in the adult nervous system
18. Phenotypic and molecular heterogeneity in fibrodysplasia ossificans progressiva
19. The Spemann organizer noggin binds and inactivates bone morphogenetic protein 4