Bone morphogenetic protein-4 regulation in fibrodysplasia ossificans progressiva

Clinical Orthopaedics and Related Research

Volumn 408, Issue , 2003, Pages 331-343

  Olmsted, Elizabeth A ^a   Kaplan, Frederick S ^a   Shore, Eileen M ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; TRANSCRIPTION FACTOR;

ADULT; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CASE REPORT; CHILD; CONNECTIVE TISSUE; ENCHONDRAL OSSIFICATION; FEMALE; GENETIC DISORDER; HALF LIFE TIME; HETEROTOPIC OSSIFICATION; HUMAN; HUMAN CELL; MALE; MOLECULAR MECHANICS; OSSIFYING MYOSITIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN STABILITY; REVERSE TRANSCRIPTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RNA STABILITY; RNA TRANSCRIPTION; STEADY STATE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 0037337134     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/00003086-200303000-00044     Document Type: Article

References (41)

1. Becker-Andre M, Hahlbrock K: Absolute mRNA quantification using the polymerase chain reaction (PCR): A novel approach by a PCR aided transcript titration assay (PATTY). Nucleic Acids Res 17:9437-9446, 1989.
2. Bushdid PB, Brantley DM, Yull FE, et al: Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis. Nature 392:615-618, 1998.
3. Chang C, Hemmati-Brivanlou A: Cell fate determination in embryonic ectoderm. J Neurobiol 36:128-151, 1998.
4. Cohen RB, Hahn GV, Tabas JA, et al: The natural history of heterotopic ossification in patients who have fibrodysplasia ossificans progressiva: A study of forty-four patients. J Bone Joint Surg 75A:215-219, 1993.
5. Connor JM, Evans CC, Evans DAP: Cardiopulmonary function in fibrodysplasia ossificans progressiva. Thorax 36:419-423, 1981.
6. Connor JM, Evans DAP: Fibrodysplasia ossificans progressiva: The clinical features and natural history of 34 patients. J Bone Joint Surg 64B:76-83, 1982.
7. Connor JM, Evans DAP: Genetic aspects of fibrodysplasia ossificans progressiva. J Med Genet 19:35-39, 1982.
8. Connor JM, Skirton H, Lunt PW: A three generation family with fibrodysplasia ossificans progressiva. J Med Genet 30:687-689, 1993.
9. Crofford U, Brahim JS, Zasloff MA, Marini JC: Failure of surgery and isotretinoin to relieve jaw immobilization in fibrodysplasia ossificans progressiva: Report of two cases. J Oral Maxillofac Surg 48:204-208, 1990.
10. Feldman G, Li M, Martin S, et al: Fibrodysplasia ossificans progressiva, a heritable disorder of severe heterotopic ossification, maps to human chromosome 4q27-31. Am J Hum Genet 66:128-135, 2000.
11. Gannon FH, Kaplan FS, Olmsted E, et al: Bone morphogenetic protein (BMP) 2/4 in early fibromatous lesions of fibrodysplasia ossificans progressiva. Hum Pathol 28:339-343, 1997.
12. Gannon FH, Valentine BA, Shore EM, et al: Acute lymphocytic infiltration in extremely early lesions of fibrodysplasia ossificans progressiva. Clin Orthop 346:19-25, 1998.
13. Greenberg ME, Bender TP: Nuclear Runoff Transcription in Mammalian Cells. In Ausubel FM, Brent R, Kingston RE, et al (eds). Short Protocols in Molecular Biology. Ed 2. New York. Wiley and Sons, Inc 4.25-4.29, 1992.
14. Heldin CH, Miyazono K, ten Dijke P: TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390:465-471, 1997.
15. Kaplan FS, McCluskey W, Hahn G, et al: Genetic transmission of fibrodysplasia ossificans progressiva: Report of a family. J Bone Joint Surg 75A:1214-1220, 1993.
16. Kaplan FS, Strear CM, Zasloff MA: Radiographic and scintigraphic features of modeling and remodeling in the heterotopic skeleton of patients who have fibrodysplasia ossificans progressiva. Clin Orthop 304:238-247, 1994.
17. Kaplan FS, Tabas JA, Gannon FH, et al: The histopathology of fibrodysplasia ossificans progressiva: An endochondral process. J Bone Joint Surg 75A:220-230, 1993.
18. Lanchoney TF, Cohen RB, Rocke DM, et al: Permanent heterotopic ossification at the injection site after diphtheria-tetanus-pertussis immunizations in children who have fibrodysplasia ossificans progressiva. J Pediatr 126:762-764, 1995.
19. Lanchoney TF, Olmsted EA, Shore EM, et al: Characterization of bone morphogenetic protein-4 receptors in fibrodysplasia ossificans progressiva. Clin Orthop 346:38-45, 1998.
20. Liu C, Wallace K. Shi C, et al: Post-transcriptional stimulation of transforming growth factor β1 mRNA by TGF-β1 treatment of transformed human osteoblasts. J Bone Miner Res 11:211-217, 1996.
21. Massagué J: TGF-beta signaling: Receptors, transducers, and Mad proteins. Cell 85:947-950, 1996.
22. Mishina Y, Suzuki A, Ueno N, Behringer RR: Bmpr encodes a type 1 bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes Dev 9:3027-3037, 1995.
23. Miyazono K: Signal transduction by bone morphogenetic protein receptors: Functional rules of Smad proteins. Bone 25:91-93, 1999.
24. Nakase T, Nomura S, Yoshikawa H, et al: Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healing. J Bone Miner Res 9:651-659, 1994.
25. Rogers MB: Receptor-selective retinoids implicate retinoic acid receptor alpha and gamma in the regulation of bmp-2 and bmp-4 in F9 embryonal carcinoma cells. Cell Growth Differ 7:115-122, 1996.
26. Sachs AB: Messenger RNA degradation in eukaryotes. Cell 74:413-421, 1993.
27. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press 1989.
28. Schmitt JM, Hwang K, Winn SR, Hollinger JO: Bone morphogenetic proteins: An update on basic biology and clinical relevance. J Orthop Res 17:269-278, 1999.
29. Schroeder HW, Zasloff M: The hand and foot malformations in fibrodysplasia ossificans progressiva. Johns Hopkins Med J 147:73-78, 1980.
30. Shafritz AB, Shore EM, Gannon FH, et al: Overexpression of an osteogenic morphogen in fibrodysplasia ossificans progressiva. N Engl J Med 335:555-561, 1996.
31. Sharrock WJ: Bone and the hematopoietic and immune systems: A report of the proceedings of a scientific workshop. J Bone Miner Res 13:537-543, 1998.
32. Shore EM, Xu M, Shah PB, et al: The human bone morphogenetic protein 4 (BMP-4) gene: Molecular structure and transcriptional regulation. Calcif Tissue Int 63:221-229, 1998.
33. Tabas JA, Hahn GV, Cohen RB, et al: Chromosomal assignment of the human gene for bone morphogenetic protein 4. Clin Orthop 293:310-316, 1993.
34. Vainio S, Karavanova I, Jowett A, Thesleff I: Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell 75:45-58, 1993.
35. Van den Wijngaard A, Pijpers MA, Joosten PH, et al: Functional characterization of two promoters in the human bone morphogenetic protein-4 gene. J Bone Miner Res 14:1432-1441, 1999.
36. Vogt TF, Duboule D: Antagonists go out on a limb. Cell 99:563-566, 1999.
37. Wang AM, Doyle MV, Mark DF: Quantitation of mRNA by the polymerase chain reaction. Proc Natl Acad Sci USA 86:9717-9721, 1989.
38. Wozney JM: The bone morphogenetic protein family and osteogenesis. Mol Reprod Dev 32:160-167, 1992.
39. Wrana JL: Regulation of Smad activity. Cell 100:189-192, 2000.
40. Xu M, Shore EM: Mutational screening of the bone morphogenetic protein 4 gene in a family with fibrodysplasia ossificans progressiva. Clin Orthop 346:53-58, 1998.
41. Zou H, Choe KM, Lu Y, et al: BMP signaling and vertebrate limb development. Cold Spring Harbor Symp Quant Biol 62:269-272, 1997.