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Volumn 93, Issue 12, 2004, Pages 2985-2993

In vitro-in vivo evaluation of supercritical processed solid dispersions: Permeability and viability assessment in Caco-2 cells

Author keywords

Bioavailability; Caco 2 cells; Carbamazepine; in vitro in vivo correlation; Mechanism of absorption; Solid dispersion; Supercritical fluids; TPGS

Indexed keywords

ALPHA TOCOPHEROL; CARBAMAZEPINE; DRUG CARRIER; GELUCIRE; GLYCOPROTEIN P; MACROGOL; TOCOFERSOLAN;

EID: 10644274441     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.20199     Document Type: Article
Times cited : (31)

References (30)
  • 1
    • 0343527392 scopus 로고    scopus 로고
    • Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards
    • Löbenberg R, Amidon GL. 2000. Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards. Eur J Pharm Biopharm 50:3-12.
    • (2000) Eur J Pharm Biopharm , vol.50 , pp. 3-12
    • Löbenberg, R.1    Amidon, G.L.2
  • 2
    • 0035800251 scopus 로고    scopus 로고
    • Processing of carbamazepine-PEG 4000 solid dispersions with supercritical carbon dioxide: Preparation, characterization, and in vitro dissolution
    • Moneghini M, Kikic I, Voinovich D, Perissutti B, Filipovic-Grcic J. 2001. Processing of carbamazepine-PEG 4000 solid dispersions with supercritical carbon dioxide: preparation, characterization, and in vitro dissolution. Int J Pharm 222:129-138.
    • (2001) Int J Pharm , vol.222 , pp. 129-138
    • Moneghini, M.1    Kikic, I.2    Voinovich, D.3    Perissutti, B.4    Filipovic-Grcic, J.5
  • 4
    • 0033230727 scopus 로고    scopus 로고
    • Strategies for particle design using supercritical fluid technologies
    • York P. 1999. Strategies for particle design using supercritical fluid technologies. Pharm Sci Tech Today 2:430-440.
    • (1999) Pharm Sci Tech Today , vol.2 , pp. 430-440
    • York, P.1
  • 5
    • 0000746640 scopus 로고
    • Gas antisolvent recrystallization: A new process to recrystallize compounds in supercritical fluids
    • Gallagher PM, Coffey MP, Krukonis VJ, Klasutis N. 1989. Gas antisolvent recrystallization: A new process to recrystallize compounds in supercritical fluids. Am Chem Soc Symp Ser 406:334-354.
    • (1989) Am Chem Soc Symp Ser , vol.406 , pp. 334-354
    • Gallagher, P.M.1    Coffey, M.P.2    Krukonis, V.J.3    Klasutis, N.4
  • 6
    • 0032885450 scopus 로고    scopus 로고
    • Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems, and recent breakthroughs
    • Serajuddin ATM. 1999. Solid dispersion of poorly water-soluble drugs: Early promises, subsequent problems, and recent breakthroughs. J Pharm Sci 88:1058-1066.
    • (1999) J Pharm Sci , vol.88 , pp. 1058-1066
    • Serajuddin, A.T.M.1
  • 7
    • 0032714228 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein by D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)
    • Dintaman JM, Silverman JA. 1999. Inhibition of P-glycoprotein by D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS). Pharm Res 16:1550-1556.
    • (1999) Pharm Res , vol.16 , pp. 1550-1556
    • Dintaman, J.M.1    Silverman, J.A.2
  • 8
    • 0034665061 scopus 로고    scopus 로고
    • The formulation of halofantrine as either non-solubilising PEG 6000 or solubilising lipid based solid dispersions: Physical stability and absolute bioavailability assessment
    • Khoo SM, Porter CJH, Charman WN. 2000. The formulation of halofantrine as either non-solubilising PEG 6000 or solubilising lipid based solid dispersions: Physical stability and absolute bioavailability assessment. Int J Pharm 205:65-78.
    • (2000) Int J Pharm , vol.205 , pp. 65-78
    • Khoo, S.M.1    Porter, C.J.H.2    Charman, W.N.3
  • 10
    • 0017946933 scopus 로고
    • Clinical pharmacokinetics of carbamazepine
    • Bertillson L. 1978. Clinical pharmacokinetics of carbamazepine. Clin Pharmacokinet 3:128-143.
    • (1978) Clin Pharmacokinet , vol.3 , pp. 128-143
    • Bertillson, L.1
  • 11
    • 0022219842 scopus 로고
    • Dissolution rates of carbamazepine and nitrazepam utilizing sugar solid dispersion system
    • Attia MA, Habib FS. 1985. Dissolution rates of carbamazepine and nitrazepam utilizing sugar solid dispersion system. Drug Dev Ind Pharm 11:1957-1969.
    • (1985) Drug Dev Ind Pharm , vol.11 , pp. 1957-1969
    • Attia, M.A.1    Habib, F.S.2
  • 12
    • 0032526833 scopus 로고    scopus 로고
    • Enhancement of carbamazepine dissolution: In vitro and in vivo evaluation
    • El-Zein H, Riad L, Abd El-Bary A. 1998. Enhancement of carbamazepine dissolution: In vitro and in vivo evaluation. Int J Pharm 168:209-220.
    • (1998) Int J Pharm , vol.168 , pp. 209-220
    • El-Zein, H.1    Riad, L.2    Abd El-Bary, A.3
  • 13
    • 0036771080 scopus 로고    scopus 로고
    • Physicochemical characterization of solid dispersions of carbamazepine formulated by supercritical carbon dioxide and conventional solvent evaporation method
    • Sethia S, Squillante E. 2002. Physicochemical characterization of solid dispersions of carbamazepine formulated by supercritical carbon dioxide and conventional solvent evaporation method. J Pharm Sci 91:1948-1957.
    • (2002) J Pharm Sci , vol.91 , pp. 1948-1957
    • Sethia, S.1    Squillante, E.2
  • 14
    • 0024593744 scopus 로고
    • Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
    • Hidalgo IJ, Raub TJ, Borchardt RT. 1989. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96:736-749.
    • (1989) Gastroenterology , vol.96 , pp. 736-749
    • Hidalgo, I.J.1    Raub, T.J.2    Borchardt, R.T.3
  • 15
    • 0029896241 scopus 로고    scopus 로고
    • Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers
    • Hosoya KI, Kim KJ, Lee VH. 1996. Age-dependent expression of P-glycoprotein gp170 in Caco-2 cell monolayers. Pharm Res 13:885-890.
    • (1996) Pharm Res , vol.13 , pp. 885-890
    • Hosoya, K.I.1    Kim, K.J.2    Lee, V.H.3
  • 16
    • 0025132942 scopus 로고
    • Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa
    • Hilgers AR, Conradi RA, Burton PS. 1990. Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa. Pharm Res 7:902-910.
    • (1990) Pharm Res , vol.7 , pp. 902-910
    • Hilgers, A.R.1    Conradi, R.A.2    Burton, P.S.3
  • 17
    • 0025899234 scopus 로고
    • Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture
    • Cory AH, Owen TC, Barltrop JA, Cory JG. 1991. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun 3:207-212.
    • (1991) Cancer Commun , vol.3 , pp. 207-212
    • Cory, A.H.1    Owen, T.C.2    Barltrop, J.A.3    Cory, J.G.4
  • 18
    • 0016437575 scopus 로고
    • Simple and reliable method for serial sampling of blood from rats
    • Upton RA. 1975. Simple and reliable method for serial sampling of blood from rats. J Pharm Sci 64:112-114.
    • (1975) J Pharm Sci , vol.64 , pp. 112-114
    • Upton, R.A.1
  • 19
    • 0019971584 scopus 로고
    • Simultaneous liquid-chromatographic determination of carbamazepine and its epoxide metabolite in plasma
    • Sawchuk RJ, Cartier LL. 1982. Simultaneous liquid-chromatographic determination of carbamazepine and its epoxide metabolite in plasma. Clin Chem 28:2127-2130.
    • (1982) Clin Chem , vol.28 , pp. 2127-2130
    • Sawchuk, R.J.1    Cartier, L.L.2
  • 20
    • 0026457774 scopus 로고
    • A new diffusion chamber system for the determination of drug permeability coefficients across the human intestinal epithelium that are independent of the unstirred water layer
    • Karlsson J, Arturson P. 1992. A new diffusion chamber system for the determination of drug permeability coefficients across the human intestinal epithelium that are independent of the unstirred water layer. Biochim Biophys Acta 1111:204-210.
    • (1992) Biochim Biophys Acta , vol.1111 , pp. 204-210
    • Karlsson, J.1    Arturson, P.2
  • 21
    • 0013966747 scopus 로고
    • New method of solid-state dispersion for increasing dissolution rates
    • Mayersohn M, Gibaldi M. 1966. New method of solid-state dispersion for increasing dissolution rates. J Pharm Sci 55:1323-1324.
    • (1966) J Pharm Sci , vol.55 , pp. 1323-1324
    • Mayersohn, M.1    Gibaldi, M.2
  • 22
    • 0013901911 scopus 로고
    • Studies on powdered preparations. XVII. Dissolution rate of sulfonamides by rotating disk method
    • Nogami H, Nagai T, Suzuki A. 1966. Studies on powdered preparations. XVII. Dissolution rate of sulfonamides by rotating disk method. Chem Pharm Bull 14:329-338.
    • (1966) Chem Pharm Bull , vol.14 , pp. 329-338
    • Nogami, H.1    Nagai, T.2    Suzuki, A.3
  • 23
    • 0002177778 scopus 로고
    • Biopharmaceutical considerations in drug formation design and evaluation
    • Kaplan SA. 1972. Biopharmaceutical considerations in drug formation design and evaluation. Drug Metab Rev 1:15-34.
    • (1972) Drug Metab Rev , vol.1 , pp. 15-34
    • Kaplan, S.A.1
  • 24
    • 0035900333 scopus 로고    scopus 로고
    • P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain
    • Potschka H, Fedrowitz M, Loscher W. 2001. P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain. Neuroreport 12:3557-3560.
    • (2001) Neuroreport , vol.12 , pp. 3557-3560
    • Potschka, H.1    Fedrowitz, M.2    Loscher, W.3
  • 26
    • 0345402723 scopus 로고
    • Human effective permeability data for atenolol, metroprolol and carbamazepine to be used in the proposed biopharmaceutical classification for IR-products
    • Lennernäs H, Knutson L, Lesko L, Salomonson T, Amidon GL. 1995. Human effective permeability data for atenolol, metroprolol and carbamazepine to be used in the proposed biopharmaceutical classification for IR-products. Pharm Res 12:8-295.
    • (1995) Pharm Res , vol.12 , pp. 8-295
    • Lennernäs, H.1    Knutson, L.2    Lesko, L.3    Salomonson, T.4    Amidon, G.L.5
  • 27
    • 0029075935 scopus 로고
    • Bisphosphonates increases tight junction permeability in the human intestinal epithelial (Caco-2) model
    • Boulenc X, Roques C, Joyeux H, Berger Y, Fabre G. 1995. Bisphosphonates increases tight junction permeability in the human intestinal epithelial (Caco-2) model. Int J Pharm 123:13-24.
    • (1995) Int J Pharm , vol.123 , pp. 13-24
    • Boulenc, X.1    Roques, C.2    Joyeux, H.3    Berger, Y.4    Fabre, G.5
  • 28
    • 0033816196 scopus 로고    scopus 로고
    • Intestinal permeation enhancers
    • Aungst BJ. 2000. Intestinal permeation enhancers. J Pharm Sci 89:429-442.
    • (2000) J Pharm Sci , vol.89 , pp. 429-442
    • Aungst, B.J.1
  • 29
    • 0017469573 scopus 로고
    • D-α-tocopheryl polyethylene glycol 1000 succinate. Acute toxicity, subchronic feeding, reproduction and teratologic studies in the rat
    • Krasavage WJ, Terhaar CJ. 1977. D-α-tocopheryl polyethylene glycol 1000 succinate. Acute toxicity, subchronic feeding, reproduction and teratologic studies in the rat. Agric Food Chem 25:273-278.
    • (1977) Agric Food Chem , vol.25 , pp. 273-278
    • Krasavage, W.J.1    Terhaar, C.J.2
  • 30
    • 0033427847 scopus 로고    scopus 로고
    • Vitamin E-TPGS increases absorption flux of an HIV protease inhibitor by enhancing its solubility and permeability
    • Yu L, Bridgers A, Polli J, Vickers A, Long S, Roy A, Winnike R, Coffin M. 1999. Vitamin E-TPGS increases absorption flux of an HIV protease inhibitor by enhancing its solubility and permeability. Pharm Res 16:1812-1817.
    • (1999) Pharm Res , vol.16 , pp. 1812-1817
    • Yu, L.1    Bridgers, A.2    Polli, J.3    Vickers, A.4    Long, S.5    Roy, A.6    Winnike, R.7    Coffin, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.