Small-sized dense magnetic pellicular support for magnetically stabilized fluidized bed adsorption of protein

Chemical Engineering Science

Volumn 60, Issue 4, 2005, Pages 917-924

  Ding, Yong ^a   Sun, Yan ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

Agarose gel; Glass bead; Magnetic field; Magnetic support; MSFB; Protein adsorption

Indexed keywords

ADSORPTION; FLOW MEASUREMENT; FLUIDIZED BEDS; MAGNETIC FIELDS; MAGNETIZATION; NEGATIVE IONS;

MAGNETIC PELLICULAR SUPPORT (MPS); MAGNETICALLY STABILIZED FLUIDIZED BED (MSFB); OPTIMUM FIELD;

PROTEINS;

ADSORPTION; FLUIDIZED BED; MAGNETIC TECHNIQUE; PROTEIN;

EID: 10644252756     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2004.09.055     Document Type: Article

References (28)

1. Barnfield Frej, A.-K., Johnsson, H.J., Johnsson, S., Leijon, P., 1997. Expanded bed adsorption at production scale: scale-up verification, process example and sanitization of column and adsorbent. Bioprocess Engineering 16, 57-63.
2. Bruce, L.J., Chase, H.A., 2001. Hydrodynamics and adsorption behaviour within an expanded bed adsorption column studied using in-bed sampling. Chemical Engineering Science 56, 3149-3162.
3. Chang, Y.K., Chase, H.A., 1996. Development of operating conditions for protein purification using expanded bed techniques: the effect of the degree of bed expansion on adsorption performance. Biotechnology and Bioengineering 49, 512-526.
4. 4 nanocolloids. Langmuir 7, 647-652.
5. Dekker, R.F.H., 1989. Immobilization of a lactase onto a magnetic support by covalent attachment to polyethyleneimine-glutaraldehyde-activated magnetite. Applied Biochemistry and Biotechnology 22, 289-310.
6. Diettrich, O., Mill, K., Johnson, Å.W., Hasilik, A., Winchester, B.C., 1998. Application of magnetic chromatography to the isolation of lysosome from fibroblasts of patients with lysosomal storage disorders. FEBS Leters 441, 369-372.
7. Franzreb, M., Hausmann, R., Hoffmann, C., Höll, W.H., 2001. Liquidphase mass transfer of magnetic ion exchangers in magnetically influenced fluidized beds I. DC fields. Reactive and Functional Polymers 46, 247-257.
8. Goto, M., Imamura, T., Hirose, T., 1995. Axial dispersion in liquid magnetically stabilized fluidized beds. Journal of Chromatography A 690, 1-8.
9. Griffith, C., Morris, J., Robichaud, M., Annen, M.J., McCormick, A.V., Flickinger, M.C., 1997. Fluidization characteristics of and protein adsorption by porous zirconium oxide particles in a fluidized-bed. Journal of Chromatography A 776, 179-195.
10. Hausmann, R., Hoffmann, C., Franzreb, M., Höll, W.H., 2000. Mass transfer rates in a liquid magnetically stabilized fluidized bed of magnetic ion-exchange particles. Chemical Engineering Science 55, 1477-1482.
11. Hou, Y. Y., Williams, R.A., 2002. Magnetic stabilisation of a liquid fluidised bed. Powder Technology 124, 287-294.
12. Kondo, A., Fukuda, H., 1997. Preparation of thermo-sensitive magnetic hydrogel microspheres and application to enzyme immobilization. Journal of Fermention and Bioengineering 84, 337-341.
13. Levenspiel, O., 1999. Chemical Reaction Engineering, third ed. Wiley, New York.
14. Liu, Y.A., Hamby, R.K., Colberg, R.D., 1991. Fundamental and practical developments of magnetofluidized beds: a review. Powder Technology 64, 3-41.
15. O'Brien, S.M., Sloane, R.P., Thomas, O.R.T., Dunnill, P., 1997. Characterisation of nonporous magnetic chelator supports and their use to recover polyhistidine-tailed T4 lysozyme from a crude E. coli. extract. Journal of Biotechnology 54, 53-67.
16. Pålsson, E., Gustavsson, P.E., Larsson, P.O., 2000. Pellicular expanded bed matrix suitable for high flow rates. Journal of Chromatography A 878, 17-25.
17. Qian, T., Liu, W., 1984. Application Handbook of Ion Exchangers, Chemical Industry Press, Beijing.
18. Serbert, K.D., Burns, M.A., 1998. Effect of hydrodynamic and magnetic stabilization on fluidized-bed adsorption. Biotechnology Progress 14, 749-755.
19. Siegell, J.H., 1987. Liquid-fluidized magnetically stabilized beds. Powder Technology 52, 139-148.
20. Thömmes, J., 1997. Fluidized bed adsorption as a primary recovery step in protein purification. Advances in Biochemical Engineering/Biotechnology 58, 185-230.
21. Thömmes, J., Weiher, M., Karau, A., Kula, M.-R., 1995. Hydrodynamics and performance in fluidized bed adsorption. Biotechnology and Bioengineering 48, 367-374.
22. Tong, X.D., Sun, Y., 2001. Agar-based magnetic affinity support for protein adsorption. Biotechnology Progress 17, 738-743.
23. Tong, X.D., Sun, Y., 2002a. Nd-Fe-B alloy-densified agarose gel for expanded bed adsorption of proteins. Journal of Chromatography A 943, 63-75.
24. Tong, X.D., Sun, Y., 2002b. Particle size and density distributions of two dense matrices in expanded bed system. Journal of Chromatography A 977, 173-183.
25. Tong, X.D., Sun, Y., 2003. Application of magnetic agarose support in liquid magnetically stabilized fluidized bed for protein adsorption. Biotechnology Progress 19, 1721-1727.
26. Webb, C., Kang, K.H., Moffat, G., Williams, R.A., Estévez, A.M., Cuéllar, J., Jaraiz, E., Galan, M.A., 1996. The magnetically stabilized fluidized bed bioreactor: a tool for improved mass transfer in immobilized enzyme systems. The Chemical Engineering Journal 61, 241-246.
27. Zhang, Z.R., O'Sullivan, D.A., Lyddiatt, A., 1999. Magnetically stabilised fluidised bed adsorption: practical benefit of uncoupling bed expansion from fluid velocities in the purification of a recombinant protein from Escherichia coli. Journal of Chemical Technology and Biotechnology 74, 270-274.
28. Zhou, X., Shi, Q.H., Bai, S., Sun, Y., 2004. Dense pellicular agarose-glass beads for expanded bed application: fabrication and characterization for effective protein adsorption. Biochemical Engineering Journal 18, 81-88.