Effect of Estradiol and Nonylphenol on mRNA Expression of Estrogen Receptors α and β, and Cytochrome P450 Aromatase in the Gonad of Chicken Embryos

Journal of Poultry Science

Volumn 39, Issue 4, 2002, Pages 302-309

  Sakimura, Masanori ^a   Tsukada, Akira ^a   Saito, Noboru ^a   Shimada, Kiyoshi ^a   Usami, Makoto ^b   Ohno, Yasuo ^b   Hanzawa, Shozo ^c  

^a NAGOYA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c NATIONAL LIVESTOCK BREEDING CENTER   (Japan)

Author keywords

endocrine disruptor; ER ; ER ; p nonylphenol; P450arom

Indexed keywords

EID: 10444267538     PISSN: 13467395     EISSN: 13490486     Source Type: Journal    
DOI: 10.2141/jpsa.39.302     Document Type: Article

References (23)

1. Bolger R, Wiese TE, Ervin K, Nestich S and Checovich W. Rapid screening of environmental chemicals for estrogen receptor binding capacity. Environmental Health Perspectives, 106: 551–557. 1998.
2. Dugaiczyk A, Haron JA, Stone EM, Dennison OE, Rothblum KN and Schwartz RJ. Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde-3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle. Biochemistry, 22: 1605–1613. 1983.
3. Giesy JP, Pierens SL, Snyder EM, Miles-Richardson S, Kramer VJ, Snyder SA, Nichols KM and Villeneuve DA. Effects of 4-nonylphenol on fecundity and biomarkers of estrogenicity in fathead minnows (Pimephales promelas). Environmental Toxicology and Chemistry, 19: 1368–1377. 2000.
4. Ichikawa K, Yamamoto I, Tsukada A, Saito N and Shimada K. cDNA cloning and mRNA expression of Japanese quail estrogen receptor α. 26th annual meeting of Japanese Avian Endocrinology. Abstract 11–12. 2001.
5. Jobling S and Sumpter JP. Detergent components in sewage effluent are weakly oestrogenic to fish: An in vitro study using rainbow trout (Oncorhynchus my kiss) hepatocytes. Aquatic Toxicology, 27: 361–372. 1993.
6. Krust A, Green S, Argos P, Kumar V, Walter P, Bornert JM and Chambon P. The chicken oestrogen receptor sequence: homology with Y-erbA and the human oestrogen and glucocorticoid receptors. The EMBO Journal, 5: 891–897. 1986.
7. Matthews J, Celius T, Halgren R and Zacharewski T. Differential estrogen receptor binding of estrogenic substances: a species comparison. Journal of Steroid Biochemistry & Molecular Biology, 74: 223–234. 2000.
8. McPhaul MJ, Noble JF, Simpson ER, Mendelson CR and Wilson JD. The expression of a functional cDNA encoding the chicken cytochrome P-450arom (aromatase) that catalyzes the formation of estrogen from androgen. The Journal of Biological Chemistry, 263: 16358–16363. 1988.
9. Nakabayashi O, Kikuchi H, Kikuchi T and Mizuno S. Differential expression of genes for aromatase and estrogen receptor during the gonadal development in chicken embryos. Journal of Molecular Endocrinology, 20: 193–202. 1998.
10. Nishikimi H, Kansaku K, Saito N, Usami M, Ohno Y and Shimada K. Sex differentiation and mRNA expression of P450c 17, P450arom and AMH in gonads of the chicken. Molecular Reproduction and Development, 55: 20–30. 2000.
11. Odum J, Tinwell H, Van Miller J, Joiner R and Ashby J. The uterotrophic activity of nonylphenol in the rat is not mediated by aromatase enzyme induction. Toxicology Letters, 115: 165–169. 2001.
12. Raymond CS, Kettlewell JR, Hirsch B, Bardwell VJ and Zarkower D. Expression of Dmrtl in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development. Developmental Biology, 215: 208–220. 1999.
13. Routledge EJ and Sumpter JP. Structural features of alkylphenolic chemicals associated with estrogenic activity. The Journal of Biological Chemistry, 272: 3280–3288. 1997.
14. Sakimura M, Hanzawa S, Tsukada A, Yamamoto I, Saito N, Usami M, Ohno Y and Shimada K. Effect of estradiol and nonylphenol on mRNA levels of vitellogenin II in the liver of chicken embryos. Journal of Poultry Science, 38: 250–257. 2001.
15. Sakimura M, Usami M, Hanzawa S, Tsukada A, Saito N, Ohno Y and Shimada K. Suppressive effect of p-nonylphenol on male-specific mRNA expression in the embryonic gonad of chickens. Journal of Poultry Science, 39: 91–99. 2002.
16. Shelby MD, Newbold RR, Tully DB, Chae K and Davis VL. Assessing environmental chemicals for estrogenicity using a combination of in vitro and in vivo assays. Environmental Health Perspectives, 104: 1296–1300. 1996.
17. Shimada K. Sex determination and sex differentiation. Avian and Poultry Biology Reviews, 13: 1–14. 2002.
18. Simpson ER, Zhao Y, Agarwal VR, Michael MD, Bulun SE, Hinshelwood MM, Graham-Lorence S, Sun T, Fisher CR, Qin K and Mendelson CR. Aromatase expression in health and disease. Recent Progress in Hormone Research, 52: 185–214. 1997.
19. Smith CA, Andrews JE and Sinclair AH. Gonadal sex differentiation in chicken embryos: Expression of estrogen receptor and aromatase genes. Journal of Steroid Biochemistry & Molecular Biology, 60: 295–302. 1997.
20. Smith CA, Smith MJ and Sinclair AH. Gene expression during gonadogenesis in the chicken embryo. Gene, 234: 395–402. 1999.
21. Warhurst AM. An environmental assessment of alkylphenol ethoxylates and alkylphenols. Friends of the Earth, London, UK. 1995.
22. White R, Jobling S, Hoare SA, Sumpter JP and Parker MG. Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology, 135: 175–182. 1994.
23. 17α hydroxylase and P450 aromatase genes in the chicken gonad before and after sexual differentiation. General and Comparative Endocrinology, 102: 233–240. 1996.