메뉴 건너뛰기




Volumn 527, Issue , 2003, Pages 243-252

Recent advances in physiological and pathological significance of tryptophan-NAD+ metabolites: Lessons from insulin-producing pancreatic β-cells

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALLOXAN; CD83 ANTIGEN; COMPLEMENTARY DNA; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; DNA; GLUCOSE; KYNURENINE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NICOTINIC ACID; NITRIC OXIDE; STREPTOZOCIN; TRYPTOPHAN;

EID: 1042268014     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0135-0_28     Document Type: Conference Paper
Times cited : (15)

References (50)
  • 1
    • 0015240479 scopus 로고
    • Kynurenine metabolism in hyperthyroidism-A biochemical basis for the low NAD(P) level in hyperthyroid rat liver
    • H. Okamoto, F. Okada, O. Hayaishi, Kynurenine metabolism in hyperthyroidism-A biochemical basis for the low NAD(P) level in hyperthyroid rat liver-, J. Biol. Chem. 246, 7759-7763 (1971).
    • (1971) J. Biol. Chem. , vol.246 , pp. 7759-7763
    • Okamoto, H.1    Okada, F.2    Hayaishi, O.3
  • 2
    • 0006224483 scopus 로고
    • Studies on xanthurenic acid III. Xanthurenic acid in the urine of diabetic patients
    • Y. Kotake, Jr., S. Tani, Studies on xanthurenic acid III. Xanthurenic acid in the urine of diabetic patients, J. Biochem. (Tokyo) 40, 295-298 (1953).
    • (1953) J. Biochem. (Tokyo) , vol.40 , pp. 295-298
    • Kotake Jr., Y.1    Tani, S.2
  • 4
    • 0036897224 scopus 로고    scopus 로고
    • Recent advances in the Okamoto model: The CD38-cyclic ADP-ribose signal system and the Reg-Reg receptor system in β-cells
    • in press
    • H. Okamoto, S. Takasawa, Recent advances in the Okamoto model: The CD38-cyclic ADP-ribose signal system and the Reg-Reg receptor system in β-cells, Diabetes (in press) 2002.
    • (2002) Diabetes
    • Okamoto, H.1    Takasawa, S.2
  • 5
    • 0019812690 scopus 로고
    • Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets
    • H. Yamamoto, Y. Uchigata, H. Okamoto, Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets, Nature 294, 284-286 (1981).
    • (1981) Nature , vol.294 , pp. 284-286
    • Yamamoto, H.1    Uchigata, Y.2    Okamoto, H.3
  • 6
    • 0019800333 scopus 로고
    • DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin
    • H. Yamamoto, Y. Uchigata, H. Okamoto, DNA strand breaks in pancreatic islets by in vivo administration of alloxan or streptozotocin, Biochem. Biophys. Res. Commun. 103, 1014-1020 (1981).
    • (1981) Biochem. Biophys. Res. Commun. , vol.103 , pp. 1014-1020
    • Yamamoto, H.1    Uchigata, Y.2    Okamoto, H.3
  • 7
    • 0019443677 scopus 로고
    • Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin-dependent diabetes
    • H. Okamoto, Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin-dependent diabetes, Mo.l Cell. Biochem. 37, 43-61 (1981).
    • (1981) Mol. Cell. Biochem. , vol.37 , pp. 43-61
    • Okamoto, H.1
  • 8
    • 0020315923 scopus 로고
    • Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis
    • Y. Uchigata, H. Yamamoto, A. Kawamura, H. Okamoto, Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis, J. Biol. Chem. 257, 6084-6088 (1982).
    • (1982) J. Biol. Chem. , vol.257 , pp. 6084-6088
    • Uchigata, Y.1    Yamamoto, H.2    Kawamura, A.3    Okamoto, H.4
  • 9
    • 84977305049 scopus 로고
    • Molecular basis of experimental diabetes: Degeneration, oncogenesis, and regeneration of pancreatic B-cells of islets of Langerhans
    • H. Okamoto, Molecular basis of experimental diabetes: degeneration, oncogenesis, and regeneration of pancreatic B-cells of islets of Langerhans, BioEssays 2, 15-21 (1985).
    • (1985) BioEssays , vol.2 , pp. 15-21
    • Okamoto, H.1
  • 11
    • 0019310901 scopus 로고
    • Protection by picolinamide, a novel inhibitor of poly(ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets
    • H. Yamamoto, H. Okamoto, Protection by picolinamide, a novel inhibitor of poly(ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets, Biochem. Biophys. Res. Commun. 95, 474-481 (1980).
    • (1980) Biochem. Biophys. Res. Commun. , vol.95 , pp. 474-481
    • Yamamoto, H.1    Okamoto, H.2
  • 13
    • 0033011114 scopus 로고    scopus 로고
    • Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin
    • V. Burkart, Z.Q. Wang, J. Radons, B. Heller, Z. Herceg, L. Stingl, E.F. Wagner, H. Kolb, Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin, Nature Med. 5, 314-319 (1999).
    • (1999) Nature Med. , vol.5 , pp. 314-319
    • Burkart, V.1    Wang, Z.Q.2    Radons, J.3    Heller, B.4    Herceg, Z.5    Stingl, L.6    Wagner, E.F.7    Kolb, H.8
  • 16
    • 0001066992 scopus 로고
    • Molecular mechanism of degeneration, oncogenesis and regeneration of pancreatic B-cells of islets of Langerhans
    • edited by E. Shafrir and A.E. Renold (John Libbey & Company Ltd, London)
    • H. Okamoto, H. Yamamoto, S. Takasawa, C. Inoue, K. Terazono, K. Shiga, M. Kitagawa, Molecular mechanism of degeneration, oncogenesis and regeneration of pancreatic B-cells of islets of Langerhans, in: Lessons from Animal Diabetes II, edited by E. Shafrir and A.E. Renold (John Libbey & Company Ltd, London, 1988), pp. 149-157.
    • (1988) Lessons from Animal Diabetes II , pp. 149-157
    • Okamoto, H.1    Yamamoto, H.2    Takasawa, S.3    Inoue, C.4    Terazono, K.5    Shiga, K.6    Kitagawa, M.7
  • 17
    • 0002423940 scopus 로고
    • The molecular basis of experimental diabetes
    • edited by H. Okamoto (Cambridge University Press, Cambridge)
    • H. Okamoto, The molecular basis of experimental diabetes, in: Molecular biology of the islets of Langerhans, edited by H. Okamoto (Cambridge University Press, Cambridge, 1990), pp. 209-231.
    • (1990) Molecular Biology of the Islets of Langerhans , pp. 209-231
    • Okamoto, H.1
  • 18
    • 0032579373 scopus 로고    scopus 로고
    • Transgenic mice overexpressing type 2 nitric oxide synthase in pancreatic β cells develop insulin-dependent diabetes without insulitis
    • T. Takamura, I. Kato, N. Kimura, T. Nakazawa, H. Yonekura, S. Takasawa, H. Okamoto, Transgenic mice overexpressing type 2 nitric oxide synthase in pancreatic β cells develop insulin-dependent diabetes without insulitis, J. Biol. Chem. 273, 2493-2496 (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 2493-2496
    • Takamura, T.1    Kato, I.2    Kimura, N.3    Nakazawa, T.4    Yonekura, H.5    Takasawa, S.6    Okamoto, H.7
  • 20
    • 0036261313 scopus 로고    scopus 로고
    • Pancreatic β-Cell death, regeneration and insulin secretion: Roles of poly(ADP-ribose) polymerase and cyclic ADP-ribose
    • S. Takasawa, H. Okamoto, Pancreatic β-Cell death, regeneration and insulin secretion: Roles of poly(ADP-ribose) polymerase and cyclic ADP-ribose, Int. J. Exp. Diabet. Res. 3, 79-96 (2002).
    • (2002) Int. J. Exp. Diabet. Res. , vol.3 , pp. 79-96
    • Takasawa, S.1    Okamoto, H.2
  • 21
    • 0034614897 scopus 로고    scopus 로고
    • Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells
    • B. Sauter, M.L. Albert, L. Francisco, M. Larsson, S. Somersan, N. Bhardwaj, Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells, J. Exp. Med. 191, 423-433 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 423-433
    • Sauter, B.1    Albert, M.L.2    Francisco, L.3    Larsson, M.4    Somersan, S.5    Bhardwaj, N.6
  • 22
    • 0035163803 scopus 로고    scopus 로고
    • Distinct modes of macrophage recognition for apoptotic and necrotic cells are not specified exclusively by phosphatidylserine exposure
    • R.E. Cocco, D.S. Ucker, Distinct modes of macrophage recognition for apoptotic and necrotic cells are not specified exclusively by phosphatidylserine exposure, Mol. Biol. Cel.l 12, 919-930 (2001).
    • (2001) Mol. Biol. Cell , vol.12 , pp. 919-930
    • Cocco, R.E.1    Ucker, D.S.2
  • 23
    • 0027393833 scopus 로고
    • Cyclic ADP-ribose in insulin secretion from pancreatic β-cells
    • S. Takasawa, K. Nata, H. Yonekura, H. Okamoto, Cyclic ADP-ribose in insulin secretion from pancreatic β-cells, Science 259, 370-373 (1993).
    • (1993) Science , vol.259 , pp. 370-373
    • Takasawa, S.1    Nata, K.2    Yonekura, H.3    Okamoto, H.4
  • 24
    • 0027501559 scopus 로고
    • Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP
    • S. Takasawa, A. Tohgo, N. Noguchi, T. Koguma, K. Nata, T. Sugimoto, H. Yonekura, H. Okamoto, Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP, J. Biol. Chem. 268, 26052-26054 (1993).
    • (1993) J. Biol. Chem. , vol.268 , pp. 26052-26054
    • Takasawa, S.1    Tohgo, A.2    Noguchi, N.3    Koguma, T.4    Nata, K.5    Sugimoto, T.6    Yonekura, H.7    Okamoto, H.8
  • 25
    • 0031051548 scopus 로고    scopus 로고
    • Lysine 129 of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) participates in the binding of ATP to inhibit the cyclic ADP-ribose hydrolase
    • A. Tohgo, H. Munakata, S. Takasawa, K. Nata, T. Akiyama, N. Hayashi, H. Okamoto, Lysine 129 of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) participates in the binding of ATP to inhibit the cyclic ADP-ribose hydrolase, J. Biol. Chem. 272, 3879-3882 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 3879-3882
    • Tohgo, A.1    Munakata, H.2    Takasawa, S.3    Nata, K.4    Akiyama, T.5    Hayashi, N.6    Okamoto, H.7
  • 29
    • 0028168459 scopus 로고
    • 2+ stores in insulin-secreting cells: Lack of effect of cADP ribose
    • 2+ stores in insulin-secreting cells: lack of effect of cADP ribose, Cell Calcium 16, 71-80 (1994).
    • (1994) Cell Calcium , vol.16 , pp. 71-80
    • Rutter, G.A.1    Theler, J.-M.2    Wollheim, C.B.3
  • 30
    • 0031465441 scopus 로고    scopus 로고
    • Cyclic ADP-ribose and the pancreatic beta cell: Where do we stand?
    • M.S, Islam, P.O. Berggren, Cyclic ADP-ribose and the pancreatic beta cell: where do we stand? Diabetologia 40, 1480-1484 (1997).
    • (1997) Diabetologia , vol.40 , pp. 1480-1484
    • Islam, M.S.1    Berggren, P.O.2
  • 31
    • 0031437662 scopus 로고    scopus 로고
    • The CD38 - Cyclic ADP-ribose signalling system in insulin secretion: Molecular basis and clinical implications
    • H. Okamoto, S. Takasawa, K. Nata, The CD38 - cyclic ADP-ribose signalling system in insulin secretion: Molecular basis and clinical implications, Diabetologia 40, 1485-1491 (1997).
    • (1997) Diabetologia , vol.40 , pp. 1485-1491
    • Okamoto, H.1    Takasawa, S.2    Nata, K.3
  • 33
    • 0036318475 scopus 로고    scopus 로고
    • 2+-ATPase (SERCA)-2 and ryanodine receptors
    • 2+- ATPase (SERCA)-2 and ryanodine receptors, Diabetes 51, S190-S201 (2002).
    • (2002) Diabetes , vol.51
    • Varadi, A.1    Rutter, G.A.2
  • 34
    • 0034816206 scopus 로고    scopus 로고
    • Significance of ecto-cyclase activity of CD38 in insulin secretion of mouse pancreatic islet cells
    • N.H. An, M.K. Han, C. Um, B.H. Park, B.J. Park, H.K. Kim, U.H. Kim, Significance of ecto-cyclase activity of CD38 in insulin secretion of mouse pancreatic islet cells, Biochem. Biophys. Res. Commun. 282, 781-786 (2001).
    • (2001) Biochem. Biophys. Res. Commun. , vol.282 , pp. 781-786
    • An, N.H.1    Han, M.K.2    Um, C.3    Park, B.H.4    Park, B.J.5    Kim, H.K.6    Kim, U.H.7
  • 35
    • 0033967246 scopus 로고    scopus 로고
    • Physiological and pathological significance of the CD38-cyclic ADP-ribose signaling system
    • H. Okamoto, S. Takasawa, K. Nata, I. Kato, A. Tohgo, N. Noguchi, Physiological and pathological significance of the CD38-cyclic ADP-ribose signaling system, Chem. Immunol. 75, 121-145 (2000).
    • (2000) Chem. Immunol. , vol.75 , pp. 121-145
    • Okamoto, H.1    Takasawa, S.2    Nata, K.3    Kato, I.4    Tohgo, A.5    Noguchi, N.6
  • 36
    • 0346759228 scopus 로고    scopus 로고
    • The CD38-cyclic ADP-ribose signal system in pancreatic β-cells. The discovery and biological significance of a novel signal system in mammalian cells
    • edited by H.C. Lee (Kluwer, Dordrecht), in press
    • S. Takasawa, H. Okamoto, The CD38-cyclic ADP-ribose signal system in pancreatic β-cells. The discovery and biological significance of a novel signal system in mammalian cells, in: Cyclic ADP-Ribose and NAADP: Structure, Metabolism and Functions, edited by H.C. Lee (Kluwer, Dordrecht, 2002), in press.
    • (2002) Cyclic ADP-Ribose and NAADP: Structure, Metabolism and Functions
    • Takasawa, S.1    Okamoto, H.2
  • 37
    • 15144357923 scopus 로고    scopus 로고
    • A missense mutation in the CD38 gene, a novel factor for insulin secretion: Association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro
    • K. Yagui, F. Shimada, M. Miura, N. Hashimoto, Y. Suzuki, Y. Tokuyama, K. Nata, A. Tohgo, F. Ikehata, S. Takasawa, H. Okamoto, H. Makino, Y. Saito, A. Kanatsuka, A missense mutation in the CD38 gene, a novel factor for insulin secretion: Association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro, Diabetologia 41, 1024-1028 (1998).
    • (1998) Diabetologia , vol.41 , pp. 1024-1028
    • Yagui, K.1    Shimada, F.2    Miura, M.3    Hashimoto, N.4    Suzuki, Y.5    Tokuyama, Y.6    Nata, K.7    Tohgo, A.8    Ikehata, F.9    Takasawa, S.10    Okamoto, H.11    Makino, H.12    Saito, Y.13    Kanatsuka, A.14
  • 38
    • 17744413214 scopus 로고    scopus 로고
    • Autoantibodies against CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) which impair glucose-induced insulin secretion in non-insulin dependent diabetes patients
    • F. Ikehata, J. Satoh, K. Nata, A. Tohgo, T. Nakazawa, I. Kato, S. Kobayashi, T. Akiyama, S. Takasawa, T. Toyota, H. Okamoto, Autoantibodies against CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) which impair glucose-induced insulin secretion in non-insulin dependent diabetes patients, J. Clin. Invest. 102, 395-401 (1998).
    • (1998) J. Clin. Invest. , vol.102 , pp. 395-401
    • Ikehata, F.1    Satoh, J.2    Nata, K.3    Tohgo, A.4    Nakazawa, T.5    Kato, I.6    Kobayashi, S.7    Akiyama, T.8    Takasawa, S.9    Toyota, T.10    Okamoto, H.11
  • 39
    • 0033512420 scopus 로고    scopus 로고
    • Autoanitibodies to CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in Caucasian patients with diabetes: Effects on insulin release from human islets
    • C. Pupilli, S. Giannini, P. Marchetti, R. Lupi, A. Antonelli, F. Malavasi, S. Takasawa, H. Okamoto, E. Ferrannini, Autoanitibodies to CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in Caucasian patients with diabetes: Effects on insulin release from human islets, Diabetes 48, 2309-2315 (1999).
    • (1999) Diabetes , vol.48 , pp. 2309-2315
    • Pupilli, C.1    Giannini, S.2    Marchetti, P.3    Lupi, R.4    Antonelli, A.5    Malavasi, F.6    Takasawa, S.7    Okamoto, H.8    Ferrannini, E.9
  • 41
    • 0035038546 scopus 로고    scopus 로고
    • Human anti-CD38 autoantibodies raise intracellular calcium and stimulate insulin release in human pancreatic islets
    • A. Antonelli, G. Baj, P. Marchetti, P. Fallahi, N. Surico, C. Pupilli, F. Malavasi, E. Ferrannini, Human anti-CD38 autoantibodies raise intracellular calcium and stimulate insulin release in human pancreatic islets, Diabetes 50, 985-991 (2001).
    • (2001) Diabetes , vol.50 , pp. 985-991
    • Antonelli, A.1    Baj, G.2    Marchetti, P.3    Fallahi, P.4    Surico, N.5    Pupilli, C.6    Malavasi, F.7    Ferrannini, E.8
  • 42
    • 0021340714 scopus 로고
    • Amelioration of Diabetes mellitus in partially depancreatized rats by poly(ADP-ribose) synthetase inhibitors: Evidence of islet B-cell regeneration
    • Y. Yonemura, T. Takashima, K. Miwa, I. Miyazaki, H. Yamamoto, H. Okamoto, Amelioration of Diabetes mellitus in partially depancreatized rats by poly(ADP-ribose) synthetase inhibitors: Evidence of islet B-cell regeneration, Diabetes 33, 401-404 (1984).
    • (1984) Diabetes , vol.33 , pp. 401-404
    • Yonemura, Y.1    Takashima, T.2    Miwa, K.3    Miyazaki, I.4    Yamamoto, H.5    Okamoto, H.6
  • 44
    • 0025320712 scopus 로고
    • Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues: The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene
    • T. Watanabe, H. Yonekura, K. Terazono, H. Yamamoto, H. Okamoto, Complete nucleotide sequence of human reg gene and its expression in normal and tumoral tissues: The reg protein, pancreatic stone protein, and pancreatic thread protein are one and the same product of the gene, J. Biol. Chem. 265, 7432-7439 (1990).
    • (1990) J. Biol. Chem. , vol.265 , pp. 7432-7439
    • Watanabe, T.1    Yonekura, H.2    Terazono, K.3    Yamamoto, H.4    Okamoto, H.5
  • 47
    • 0031792577 scopus 로고    scopus 로고
    • Amelioration of diabetes in nonobese diabetic mice with advanced disease by Linomide-induced immunoregulation combined with Reg protein treatment
    • D.J. Gross, L. Weiss, I. Reibstein, J. van den Brand, H. Okamoto, A. Clark, S. Slavin, Amelioration of diabetes in nonobese diabetic mice with advanced disease by Linomide-induced immunoregulation combined with Reg protein treatment, Endocrinology 139, 2369-2374 (1998).
    • (1998) Endocrinology , vol.139 , pp. 2369-2374
    • Gross, D.J.1    Weiss, L.2    Reibstein, I.3    Van Den Brand, J.4    Okamoto, H.5    Clark, A.6    Slavin, S.7
  • 48
    • 0033286202 scopus 로고    scopus 로고
    • The Reg gene family and Reg proteins: With special attention to the regeneration of pancreatic β-cells
    • H. Okamoto, The Reg gene family and Reg proteins: With special attention to the regeneration of pancreatic β-cells, J. Hepatobiliary Pancreat. Surg. 6, 254-262 (1999).
    • (1999) J. Hepatobiliary Pancreat. Surg. , vol.6 , pp. 254-262
    • Okamoto, H.1
  • 49
  • 50
    • 17944385649 scopus 로고    scopus 로고
    • Activation of Reg gene, a gene for insulin-producing β-cell regeneration: Poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosyl)ation
    • T. Akiyama, S. Takasawa, K. Nata, S. Kobayashi, M. Abe, N.J. Shervani, T. Ikeda, K. Nakagawa, M. Unno, S. Matsuno, H. Okamoto, Activation of Reg gene, a gene for insulin-producing β-cell regeneration: Poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosyl)ation, PNAS 99, 48-53 (2001).
    • (2001) PNAS , vol.99 , pp. 48-53
    • Akiyama, T.1    Takasawa, S.2    Nata, K.3    Kobayashi, S.4    Abe, M.5    Shervani, N.J.6    Ikeda, T.7    Nakagawa, K.8    Unno, M.9    Matsuno, S.10    Okamoto, H.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.