-
2
-
-
0025285086
-
Lessons learned from molecular biology of insulin gene mutations
-
Steiner, D.F., H.S. Tager, S.J. Chan, K. Nanjo, T. Sanke, and A.H. Rubenstein. 1990. Lessons learned from molecular biology of insulin gene mutations. Diabetes Care. 13:600-609.
-
(1990)
Diabetes Care
, vol.13
, pp. 600-609
-
-
Steiner, D.F.1
Tager, H.S.2
Chan, S.J.3
Nanjo, K.4
Sanke, T.5
Rubenstein, A.H.6
-
3
-
-
2642702808
-
Abnormal products of the human insulin gene
-
H. Okamoto, editor. Cambridge University Press, Cambridge, UK
-
Tager, H.S. 1990. Abnormal products of the human insulin gene. In Molecular Biology of the Islets of Langerhans. H. Okamoto, editor. Cambridge University Press, Cambridge, UK. 263-286.
-
(1990)
Molecular Biology of the Islets of Langerhans
, pp. 263-286
-
-
Tager, H.S.1
-
4
-
-
0026761432
-
Mutations in the insulin receptor gene
-
Taylor, S.I., A. Cama, and D. Accili. 1992. Mutations in the insulin receptor gene. Endocr. Rev. 13:566-595.
-
(1992)
Endocr. Rev.
, vol.13
, pp. 566-595
-
-
Taylor, S.I.1
Cama, A.2
Accili, D.3
-
5
-
-
0001489225
-
Molecular aspects of insulin action
-
C.R. Kahn and G.C. Weir, editors. Lea & Febiger, Philadelphia, PA
-
White, M.F., and C.R. Kahn. 1994. Molecular aspects of insulin action. In Joslin's Diabetes Mellitus, 13th Ed. C.R. Kahn and G.C. Weir, editors. Lea & Febiger, Philadelphia, PA. 139-162.
-
(1994)
Joslin's Diabetes Mellitus, 13th Ed.
, pp. 139-162
-
-
White, M.F.1
Kahn, C.R.2
-
6
-
-
0027472126
-
Familial hyperglycemia due to mutation in glucokinase: Definition of a subtype of diabetes mellitus
-
Froguel, P., H. Zouali, N. Vionnet, G. Velho, M. Vaxillaire, F. Sun, S. Lesage, M. Stoffel, J. Takeda, P. Passa, et al. 1993. Familial hyperglycemia due to mutation in glucokinase: definition of a subtype of diabetes mellitus. N. Eng. J. Med. 328:697-702.
-
(1993)
N. Eng. J. Med.
, vol.328
, pp. 697-702
-
-
Froguel, P.1
Zouali, H.2
Vionnet, N.3
Velho, G.4
Vaxillaire, M.5
Sun, F.6
Lesage, S.7
Stoffel, M.8
Takeda, J.9
Passa, P.10
-
7
-
-
0026583193
-
Linkage of type 2 diabetes to the glucokinase gene
-
Hattersley, A.T., R.C. Turner, M.A. Permutt, P. Patel, Y. Tanizawa, K.C. Chiu, S. O'Rahilly, P.J. Watkins, and J.S. Wainscoat. 1992. Linkage of type 2 diabetes to the glucokinase gene. Lancet. 339:1307-1310.
-
(1992)
Lancet
, vol.339
, pp. 1307-1310
-
-
Hattersley, A.T.1
Turner, R.C.2
Permutt, M.A.3
Patel, P.4
Tanizawa, Y.5
Chiu, K.C.6
O'Rahilly, S.7
Watkins, P.J.8
Wainscoat, J.S.9
-
8
-
-
10544236911
-
Mutations in hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1)
-
Yamagata, K., H. Furuta, N. Oda, P.J. Kaisaki, S. Menzel, N.J. Cox, S.S. Fajans, S. Signorini, M. Stoffel, and G.I. Bell. 1996. Mutations in hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1). Nature. 384:458-460.
-
(1996)
Nature
, vol.384
, pp. 458-460
-
-
Yamagata, K.1
Furuta, H.2
Oda, N.3
Kaisaki, P.J.4
Menzel, S.5
Cox, N.J.6
Fajans, S.S.7
Signorini, S.8
Stoffel, M.9
Bell, G.I.10
-
9
-
-
10544249874
-
Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)
-
Yamagata, K., N. Oda, P.J. Kaisaki, S. Menzel, H. Furuta, M. Vaxillaire, L. Southam, R.D. Cox, G.M. Lathrop, V.V. Boriraj, et al. 1996. Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3). Nature. 384:455-458.
-
(1996)
Nature
, vol.384
, pp. 455-458
-
-
Yamagata, K.1
Oda, N.2
Kaisaki, P.J.3
Menzel, S.4
Furuta, H.5
Vaxillaire, M.6
Southam, L.7
Cox, R.D.8
Lathrop, G.M.9
Boriraj, V.V.10
-
10
-
-
0026849690
-
Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion
-
Ballinger, S.W., J.M. Shoffner, E.V. Hedaya, I. Trounce, M.A. Polak, D.A. Koontz, and D.C. Wallace. 1992. Maternally transmitted diabetes and deafness associated with a 10.4 kb mitochondrial DNA deletion. Nat. Genet. 1: 11-15.
-
(1992)
Nat. Genet.
, vol.1
, pp. 11-15
-
-
Ballinger, S.W.1
Shoffner, J.M.2
Hedaya, E.V.3
Trounce, I.4
Polak, M.A.5
Koontz, D.A.6
Wallace, D.C.7
-
11
-
-
0026906885
-
Leu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness
-
Leu(UUR) gene in a large pedigree with maternally transmitted type II diabetes mellitus and deafness. Nat. Genet. 1:368-371.
-
(1992)
Nat. Genet.
, vol.1
, pp. 368-371
-
-
Van Der Ouweland, J.M.V.1
Lemkes, H.H.P.J.2
Ruitenbeek, W.3
Sandkuijl, L.A.4
De Vijlder, M.F.5
Struyvenberg, P.A.A.6
Van De Kamp, J.J.P.7
Maassen, J.A.8
-
12
-
-
0027393833
-
Cyclic ADP-ribose in insulin secretion from pancreatic β cells
-
Takasawa, S., K. Nata, H. Yonekura, and U. Okamoto. 1993. Cyclic ADP-ribose in insulin secretion from pancreatic β cells. Science. 259:370-373.
-
(1993)
Science
, vol.259
, pp. 370-373
-
-
Takasawa, S.1
Nata, K.2
Yonekura, H.3
Okamoto, U.4
-
13
-
-
0029129832
-
New aspects of the physiological significance of NAD, poly ADP-ribose and cyclic ADP-ribose
-
Okamoto, H., S. Takasawa, and A. Tohgo. 1995. New aspects of the physiological significance of NAD, poly ADP-ribose and cyclic ADP-ribose. Biochimie (Paris). 77:356-363.
-
(1995)
Biochimie (Paris)
, vol.77
, pp. 356-363
-
-
Okamoto, H.1
Takasawa, S.2
Tohgo, A.3
-
14
-
-
0031420602
-
Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38: Inhibition of hydrolysis by ATP and the physiological significance
-
Okamoto, H., S. Takasawa, A. Tohgo, K. Nata, I. Kato, and N. Noguchi. 1997. Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38: inhibition of hydrolysis by ATP and the physiological significance. Methods Enzymol. 280:306-318.
-
(1997)
Methods Enzymol.
, vol.280
, pp. 306-318
-
-
Okamoto, H.1
Takasawa, S.2
Tohgo, A.3
Nata, K.4
Kato, I.5
Noguchi, N.6
-
15
-
-
0031437662
-
The CD38-cyclic ADP-ribose signalling system in insulin secretion: Molecular basis and clinical implications
-
Okamoto, H., S. Takasawa, and K. Nata. 1997. The CD38-cyclic ADP-ribose signalling system in insulin secretion: molecular basis and clinical implications. Diabetologia. 40:1485-1491.
-
(1997)
Diabetologia
, vol.40
, pp. 1485-1491
-
-
Okamoto, H.1
Takasawa, S.2
Nata, K.3
-
16
-
-
0029589269
-
Regulatory role of CD38 ( ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in insulin secretion by glucose in pancreatic β cells. Enhanced insulin secretion in CD38-expressing transgenic mice
-
Kato, I., S. Takasawa, A. Akabane, O. Tanaka, H. Abe, T. Takamura, Y. Suzuki, K. Nata, H. Yonekura, T. Yoshimoto, and H. Okamoto. 1995. Regulatory role of CD38 ( ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) in insulin secretion by glucose in pancreatic β cells. Enhanced insulin secretion in CD38-expressing transgenic mice. J. Biol. Chem. 270:30045-30050.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 30045-30050
-
-
Kato, I.1
Takasawa, S.2
Akabane, A.3
Tanaka, O.4
Abe, H.5
Takamura, T.6
Suzuki, Y.7
Nata, K.8
Yonekura, H.9
Yoshimoto, T.10
Okamoto, H.11
-
17
-
-
0027501559
-
Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP
-
Takasawa, S., A. Tohgo, N. Noguchi, T. Koguma, K. Nata, T. Sugimoto, H. Yonekura, and H. Okamoto. 1993. Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38 and inhibition of the hydrolysis by ATP. J. Biol. Chem. 268:26052-26054.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 26052-26054
-
-
Takasawa, S.1
Tohgo, A.2
Noguchi, N.3
Koguma, T.4
Nata, K.5
Sugimoto, T.6
Yonekura, H.7
Okamoto, H.8
-
18
-
-
0031051548
-
Lysine 129 of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) participates in the binding of ATP to inhibit the cyclic ADP-ribose hydrolase
-
Tohgo, A., H. Munakata, S. Takasawa, K. Nata, T. Akiyama, N. Hayashi, and H. Okamoto. 1997. Lysine 129 of CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase) participates in the binding of ATP to inhibit the cyclic ADP-ribose hydrolase. J. Biol. Chem. 272:3879-3882.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3879-3882
-
-
Tohgo, A.1
Munakata, H.2
Takasawa, S.3
Nata, K.4
Akiyama, T.5
Hayashi, N.6
Okamoto, H.7
-
19
-
-
0029616708
-
2+ mobilization
-
2+ mobilization. J. Biol. Chem. 270:30257-30259.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 30257-30259
-
-
Takasawa, S.1
Ishida, A.2
Nata, K.3
Nakagawa, K.4
Noguchi, N.5
Tohgo, A.6
Kato, I.7
Yonekura, H.8
Fujisawa, H.9
Okamoto, H.10
-
20
-
-
0031013367
-
2+ from islet microsomes
-
2+ from islet microsomes. J. Biol. Chem. 272:3133-3136.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3133-3136
-
-
Noguchi, N.1
Takasawa, S.2
Nata, K.3
Tohgo, A.4
Kato, I.5
Ikehata, F.6
Yonekura, H.7
Okamoto, H.8
-
21
-
-
0032579402
-
2+ mobilization in normal and diabetic β-cells
-
2+ mobilization in normal and diabetic β-cells. J. Biol. Chem. 273:2497-2500.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2497-2500
-
-
Takasawa, S.1
Akiyama, T.2
Nata, K.3
Kuroki, M.4
Tohgo, A.5
Noguchi, N.6
Kobayashi, S.7
Kato, I.8
Katada, T.9
Okamoto, H.10
-
25
-
-
0029120736
-
Expression of CD38 gene, but not of mitochondrial glycerol-3-phosphate dehydrogenase gene, is impaired in pancreatic islets of GK rats
-
Matsuoka, T., Y. Kajimoto, H. Watada, Y. Umayahara, M. Kubota, R. Kawamori, Y. Yamasaki, and T. Kamada. 1995. Expression of CD38 gene, but not of mitochondrial glycerol-3-phosphate dehydrogenase gene, is impaired in pancreatic islets of GK rats. Biochem. Biophys. Res. Commun. 214:239-246.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.214
, pp. 239-246
-
-
Matsuoka, T.1
Kajimoto, Y.2
Watada, H.3
Umayahara, Y.4
Kubota, M.5
Kawamori, R.6
Yamasaki, Y.7
Kamada, T.8
-
26
-
-
0021776150
-
-
Diabetes mellitus: report of a WHO study group. 1985. WHO Tech. Rep. Ser. 727:1-113.
-
(1985)
WHO Tech. Rep. Ser.
, vol.727
, pp. 1-113
-
-
-
27
-
-
0030916182
-
Role of cyclic ADP-ribose in ATP-activated potassium currents in alveolar macrophages
-
Ebihara, S., T. Sasaki, W. Hida, Y. Kikuchi, T. Oshiro, S. Shimura, S. Takasawa, H. Okamoto, A. Nishiyama, N. Akaike, and K. Shirato. 1997. Role of cyclic ADP-ribose in ATP-activated potassium currents in alveolar macrophages. J. Biol. Chem. 272:16023-16029.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16023-16029
-
-
Ebihara, S.1
Sasaki, T.2
Hida, W.3
Kikuchi, Y.4
Oshiro, T.5
Shimura, S.6
Takasawa, S.7
Okamoto, H.8
Nishiyama, A.9
Akaike, N.10
Shirato, K.11
-
28
-
-
0029924210
-
Inositol 1,4,5-trisphosphate receptor subtype 3 in pancreatic islet cell secretory granules revisited
-
Ravazzola, M., P.A. Halvan, and L. Orci. 1996. Inositol 1,4,5-trisphosphate receptor subtype 3 in pancreatic islet cell secretory granules revisited. Proc. Natl. Acad. Sci. USA. 93:2745-2748.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2745-2748
-
-
Ravazzola, M.1
Halvan, P.A.2
Orci, L.3
-
29
-
-
0028085717
-
Cloning and characterization of cDNA encoding rat ADP-rihosyl cyclase/cyclic ADP-ribose hydrolase (homologue to human CD38) from islets of Langerhans
-
Koguma, T., S. Takasawa, A. Tohgo, T. Karasawa, Y. Furuya, H. Yonekura, and H. Okamoto. 1994. Cloning and characterization of cDNA encoding rat ADP-rihosyl cyclase/cyclic ADP-ribose hydrolase (homologue to human CD38) from islets of Langerhans. Biochim. Biophys. Acta. 1223:160-162.
-
(1994)
Biochim. Biophys. Acta
, vol.1223
, pp. 160-162
-
-
Koguma, T.1
Takasawa, S.2
Tohgo, A.3
Karasawa, T.4
Furuya, Y.5
Yonekura, H.6
Okamoto, H.7
-
30
-
-
18844471424
-
Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): Organization, nucleotide sequence and alternative splicing
-
Nata, K., T. Takamura, T. Karasawa, T. Kumagai, W. Hashioka, A. Tohgo, H. Yonekura, S. Takasawa, S. Nakamura, and H. Okamoto. 1997. Human gene encoding CD38 (ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase): organization, nucleotide sequence and alternative splicing. Gene. 186: 285-292.
-
(1997)
Gene
, vol.186
, pp. 285-292
-
-
Nata, K.1
Takamura, T.2
Karasawa, T.3
Kumagai, T.4
Hashioka, W.5
Tohgo, A.6
Yonekura, H.7
Takasawa, S.8
Nakamura, S.9
Okamoto, H.10
-
31
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
32
-
-
0029143465
-
Accumulation of cyclic ADP-ribose measured by a specific radioimmunoassay in differentiated human leukemic HL-60 cells with all-trans-retinoic acid
-
Takahashi, K., I. Kukimoto, K.I. Tokita, K. Inageda, S.I. Inoue, K. Kontani, S.I. Hoshino, H. Nishina, Y. Kanaho, and T. Katada. 1995. Accumulation of cyclic ADP-ribose measured by a specific radioimmunoassay in differentiated human leukemic HL-60 cells with all-trans-retinoic acid. FEBS Lett. 371: 204-208.
-
(1995)
FEBS Lett.
, vol.371
, pp. 204-208
-
-
Takahashi, K.1
Kukimoto, I.2
Tokita, K.I.3
Inageda, K.4
Inoue, S.I.5
Kontani, K.6
Hoshino, S.I.7
Nishina, H.8
Kanaho, Y.9
Katada, T.10
-
33
-
-
2642642324
-
Modulation of insulin secretion by CD38 antibodies
-
Itoh, T., A. Taminato, Y. Kato, H. Natsume, Y. Suzuki, G. Sarwar, and T. Yoshimi. 1997. Modulation of insulin secretion by CD38 antibodies. J. Jpn. Diabetes Soc. 40:211.
-
(1997)
J. Jpn. Diabetes Soc.
, vol.40
, pp. 211
-
-
Itoh, T.1
Taminato, A.2
Kato, Y.3
Natsume, H.4
Suzuki, Y.5
Sarwar, G.6
Yoshimi, T.7
-
34
-
-
15144357923
-
A missense mutation in the CD38 gene, a novel factor for insulin secretion: Association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro
-
In press
-
Yagui, K., F. Shimada, M. Miura, N. Hashimoto, Y. Suzuki, Y. Tokuyama, K. Nata, A. Tohgo, F. Ikehata, S. Takasawa, et al. 1998. A missense mutation in the CD38 gene, a novel factor for insulin secretion: association with Type II diabetes mellitus in Japanese subjects and evidence of abnormal function when expressed in vitro. Diabeteologia. In press.
-
(1998)
Diabeteologia
-
-
Yagui, K.1
Shimada, F.2
Miura, M.3
Hashimoto, N.4
Suzuki, Y.5
Tokuyama, Y.6
Nata, K.7
Tohgo, A.8
Ikehata, F.9
Takasawa, S.10
-
35
-
-
0028294981
-
Control of cytosolic free calcium in cultured human pancreatic β-cells occurs by external calcium-dependent and independent mechanism
-
Rojas, E., P.B. Carroll, C. Ricordi, A.C. Boschero, S.S. Stojilkonic, and I. Atwater. 1994. Control of cytosolic free calcium in cultured human pancreatic β-cells occurs by external calcium-dependent and independent mechanism. Endocrinology. 134:1771-1781.
-
(1994)
Endocrinology
, vol.134
, pp. 1771-1781
-
-
Rojas, E.1
Carroll, P.B.2
Ricordi, C.3
Boschero, A.C.4
Stojilkonic, S.S.5
Atwater, I.6
-
36
-
-
0002955624
-
Mechanism of insulin secretion
-
F.M. Ashcroft and S.J.H Ashcroft, editors. IRL Press, Oxford, UK
-
Ashcroft, P.M., and S.J.H. Ashcroft. 1992. Mechanism of insulin secretion. In Insulin: Molecular Biology to Pathology. F.M. Ashcroft and S.J.H Ashcroft, editors. IRL Press, Oxford, UK. 97-150.
-
(1992)
Insulin: Molecular Biology to Pathology
, pp. 97-150
-
-
Ashcroft, P.M.1
Ashcroft, S.J.H.2
-
37
-
-
2642712691
-
Anti-CD38 antibody as a novel autoantibody in IDDM: Studies in NOD mice
-
Taminato, A., T. Itoh, H. Natsume, Y. Kato, Y. Suzuki, T. Yoshimi, and S. Makino. 1997. Anti-CD38 antibody as a novel autoantibody in IDDM: studies in NOD mice. J. Jpn. Diabetes Soc. 40:203.
-
(1997)
J. Jpn. Diabetes Soc.
, vol.40
, pp. 203
-
-
Taminato, A.1
Itoh, T.2
Natsume, H.3
Kato, Y.4
Suzuki, Y.5
Yoshimi, T.6
Makino, S.7
|