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Volumn 10, Issue 12, 2004, Pages 815-825

Graft-versus-host disease: How to translate new insights into new therapeutic strategies

Author keywords

Alemtuzumab; ATG; Extracorporeal photophoresis; Graft versus host disease; MMR; Pento statin; Sirolimus; Stem cell transplant; T cell depletion

Indexed keywords

ADALIMUMAB; ALEMTUZUMAB; CORTICOSTEROID; CYCLOSPORIN; DACLIZUMAB; DENILEUKIN DIFTITOX; ETANERCEPT; INFLIXIMAB; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR BLOCKING AGENT; METHOTREXATE; METHOXSALEN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NATURAL KILLER CELL RECEPTOR NKG2D; PENTOSTATIN; RAPAMYCIN; RECEPTOR BLOCKING AGENT; TACROLIMUS; THYMOCYTE ANTIBODY; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG;

EID: 10344252879     PISSN: 10838791     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbmt.2004.10.005     Document Type: Review
Times cited : (26)

References (76)
  • 1
    • 0004647768 scopus 로고
    • The effect of adult chicken organ graft on the chick embryo
    • J. Murphy The effect of adult chicken organ graft on the chick embryo J Exp Med 24 1916 1-6
    • (1916) J. Exp. Med. , vol.24 , pp. 1-6
    • Murphy, J.1
  • 2
    • 0001426462 scopus 로고
    • Quantitative studies on tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of runt disease
    • R. Billingham L. Brent Quantitative studies on tissue transplantation immunity. IV. Induction of tolerance in newborn mice and studies on the phenomenon of runt disease Philos Trans R Soc Lond 242 1959 439-477
    • (1959) Philos. Trans. R Soc. Lond. , vol.242 , pp. 439-477
    • Billingham, R.1    Brent, L.2
  • 3
    • 0013989358 scopus 로고
    • The biology of graft-versus-host reactions
    • R.E. Billingham The biology of graft-versus-host reactions Harvey Lect 62 1966 21-78
    • (1966) Harvey Lect. , vol.62 , pp. 21-78
    • Billingham, R.E.1
  • 4
    • 0028208934 scopus 로고
    • Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice
    • C.Q. Xun J.S. Thompson C.D. Jennings et al. Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice Blood 83 1994 2360-2367
    • (1994) Blood , vol.83 , pp. 2360-2367
    • Xun, C.Q.1    Thompson, J.S.2    Jennings, C.D.3
  • 5
    • 0033575383 scopus 로고    scopus 로고
    • Prevention of graft versus host disease by inactivation of host antigen-presenting cells
    • W.D. Shlomchik M.S. Couzens C.B. Tang et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells Science 285 1999 412-415
    • (1999) Science , vol.285 , pp. 412-415
    • Shlomchik, W.D.1    Couzens, M.S.2    Tang, C.B.3
  • 6
    • 0036281797 scopus 로고    scopus 로고
    • Acute graft-versus-host disease does not require alloantigen expression on host epithelium
    • T. Teshima R. Ordemann P. Reddy et al. Acute graft-versus-host disease does not require alloantigen expression on host epithelium Nat Med 8 2002 575-581
    • (2002) Nat. Med. , vol.8 , pp. 575-581
    • Teshima, T.1    Ordemann, R.2    Reddy, P.3
  • 7
    • 2442417361 scopus 로고    scopus 로고
    • Graft-versus-host disease of the skin: Life and death on the epidermal edge
    • C.C. Hofmeister A. Quinn K.R. Cooke et al. Graft-versus-host disease of the skin: Life and death on the epidermal edge Biol Blood Marrow Transplant 10 2004 366-372
    • (2004) Biol. Blood Marrow Transplant , vol.10 , pp. 366-372
    • Hofmeister, C.C.1    Quinn, A.2    Cooke, K.R.3
  • 8
    • 0034193057 scopus 로고    scopus 로고
    • The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: Rationale for the use of cytokine shields in allogeneic bone marrow transplantation
    • G.R. Hill J.L. Ferrara The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: Rationale for the use of cytokine shields in allogeneic bone marrow transplantation Blood 95 2000 2754-2759
    • (2000) Blood , vol.95 , pp. 2754-2759
    • Hill, G.R.1    Ferrara, J.L.2
  • 9
    • 0035854479 scopus 로고    scopus 로고
    • Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
    • F. Paris Z. Fuks A. Kang et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice Science 293 2001 293-297
    • (2001) Science , vol.293 , pp. 293-297
    • Paris, F.1    Fuks, Z.2    Kang, A.3
  • 10
    • 84983719872 scopus 로고    scopus 로고
    • Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic-cell transplantation
    • M.T. Lin B. Storer P.J. Martin et al. Relation of an interleukin-10 promoter polymorphism to graft-versus-host disease and survival after hematopoietic-cell transplantation N Engl J Med 349 2003 2201-2210
    • (2003) N. Engl. J. Med. , vol.349 , pp. 2201-2210
    • Lin, M.T.1    Storer, B.2    Martin, P.J.3
  • 11
    • 1942425017 scopus 로고    scopus 로고
    • Interleukin-10 and tumor necrosis factor alpha region haplotypes predict transplant-related mortality after unrelated donor stem cell transplantation
    • L.J. Keen T.E. DeFor J.L. Bidwell et al. Interleukin-10 and tumor necrosis factor alpha region haplotypes predict transplant-related mortality after unrelated donor stem cell transplantation Blood 103 2004 3599-3602
    • (2004) Blood , vol.103 , pp. 3599-3602
    • Keen, L.J.1    DeFor, T.E.2    Bidwell, J.L.3
  • 13
    • 0001624906 scopus 로고    scopus 로고
    • T cell death and transplantation tolerance
    • X.C. Li T.B. Strom L.A. Turka et al. T cell death and transplantation tolerance Immunity 14 2001 407-416
    • (2001) Immunity , vol.14 , pp. 407-416
    • Li, X.C.1    Strom, T.B.2    Turka, L.A.3
  • 14
    • 0037093217 scopus 로고    scopus 로고
    • The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality
    • P.A. Taylor C.J. Lees B.R. Blazar The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality Blood 99 2002 3493-3499
    • (2002) Blood , vol.99 , pp. 3493-3499
    • Taylor, P.A.1    Lees, C.J.2    Blazar, B.R.3
  • 15
    • 9144261074 scopus 로고    scopus 로고
    • CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans
    • M. Stanzani S.L. Martins R.M. Saliba et al. CD25 expression on donor CD4+ or CD8+ T cells is associated with an increased risk for graft-versus-host disease after HLA-identical stem cell transplantation in humans Blood 103 2004 1140-1146
    • (2004) Blood , vol.103 , pp. 1140-1146
    • Stanzani, M.1    Martins, S.L.2    Saliba, R.M.3
  • 16
    • 4644301368 scopus 로고    scopus 로고
    • Association of Foxp3 regulatory gene expression with graft-versus-host disease
    • Y. Miura C.J. Thoburn E.C. Bright et al. Association of Foxp3 regulatory gene expression with graft-versus-host disease Blood 104 2004 2187-2193
    • (2004) Blood , vol.104 , pp. 2187-2193
    • Miura, Y.1    Thoburn, C.J.2    Bright, E.C.3
  • 17
    • 0026457877 scopus 로고
    • Host-specific interleukin-2-secreting donor T-cell precursors as predictors of acute graft-versus-host disease in bone marrow transplantation between HLA-identical siblings
    • M. Theobald T. Nierle D. Bunjes et al. Host-specific interleukin-2-secreting donor T-cell precursors as predictors of acute graft-versus-host disease in bone marrow transplantation between HLA-identical siblings N Engl J Med 327 1992 1613-1617
    • (1992) N. Engl. J. Med. , vol.327 , pp. 1613-1617
    • Theobald, M.1    Nierle, T.2    Bunjes, D.3
  • 18
    • 0036831613 scopus 로고    scopus 로고
    • New aspects of natural-killer-cell surveillance and therapy of cancer
    • M.J. Smyth Y. Hayakawa K. Takeda et al. New aspects of natural-killer-cell surveillance and therapy of cancer Nat Rev Cancer 2 2002 850-861
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 850-861
    • Smyth, M.J.1    Hayakawa, Y.2    Takeda, K.3
  • 19
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • L. Ruggeri M. Capanni E. Urbani et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants Science 295 2002 2097-2100
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3
  • 20
    • 10744226751 scopus 로고    scopus 로고
    • Acute and chronic graft-versus-host disease after ablative and nonmyeloablative conditioning for allogeneic hematopoietic transplantation
    • D.R. Couriel R.M. Saliba S. Giralt et al. Acute and chronic graft-versus-host disease after ablative and nonmyeloablative conditioning for allogeneic hematopoietic transplantation Biol Blood Marrow Transplant 10 2004 178-185
    • (2004) Biol. Blood Marrow Transplant , vol.10 , pp. 178-185
    • Couriel, D.R.1    Saliba, R.M.2    Giralt, S.3
  • 21
    • 0038494593 scopus 로고    scopus 로고
    • Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation
    • M. Mielcarek P.J. Martin W. Leisenring et al. Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation Blood 102 2003 756-762
    • (2003) Blood , vol.102 , pp. 756-762
    • Mielcarek, M.1    Martin, P.J.2    Leisenring, W.3
  • 22
    • 11944270723 scopus 로고
    • Modulation of acute graft-versus-host-disease after allogeneic bone marrow transplantation by tumor necrosis factor alpha (TNF alpha) release in the course of pretransplant conditioning: Role of conditioning regimens and prophylactic application of a monoclonal antibody neutralizing human TNF alpha (MAK 195F)
    • E. Holler H.J. Kolb J. Mittermuller et al. Modulation of acute graft-versus-host-disease after allogeneic bone marrow transplantation by tumor necrosis factor alpha (TNF alpha) release in the course of pretransplant conditioning: Role of conditioning regimens and prophylactic application of a monoclonal antibody neutralizing human TNF alpha (MAK 195F) Blood 86 1995 890-899
    • (1995) Blood , vol.86 , pp. 890-899
    • Holler, E.1    Kolb, H.J.2    Mittermuller, J.3
  • 23
    • 0025766133 scopus 로고
    • Prevention of acute GVHD by in vivo use of anti-interleukin-2 receptor monoclonal antibody (33B3.1): A feasibility trial in 15 patients
    • D. Blaise D. Olive M. Hirn et al. Prevention of acute GVHD by in vivo use of anti-interleukin-2 receptor monoclonal antibody (33B3.1): A feasibility trial in 15 patients Bone Marrow Transplant 8 1991 105-111
    • (1991) Bone Marrow Transplant , vol.8 , pp. 105-111
    • Blaise, D.1    Olive, D.2    Hirn, M.3
  • 24
    • 0025890101 scopus 로고
    • Prophylaxis of graft-versus-host disease by administration of the murine anti-IL-2 receptor antibody 2A3
    • C. Anasetti P.J. Martin R. Storb et al. Prophylaxis of graft-versus-host disease by administration of the murine anti-IL-2 receptor antibody 2A3 Bone Marrow Transplant 7 1991 375-381
    • (1991) Bone Marrow Transplant , vol.7 , pp. 375-381
    • Anasetti, C.1    Martin, P.J.2    Storb, R.3
  • 25
    • 2442642825 scopus 로고    scopus 로고
    • A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease
    • K.B. Miller T.F. Roberts G. Chan et al. A novel reduced intensity regimen for allogeneic hematopoietic stem cell transplantation associated with a reduced incidence of graft-versus-host disease Bone Marrow Transplant 33 2004 881-889
    • (2004) Bone Marrow Transplant , vol.33 , pp. 881-889
    • Miller, K.B.1    Roberts, T.F.2    Chan, G.3
  • 26
    • 0034307366 scopus 로고    scopus 로고
    • In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation
    • P.D. Kottaridis D.W. Milligan R. Chopra et al. In vivo CAMPATH-1H prevents graft-versus-host disease following nonmyeloablative stem cell transplantation Blood 96 2000 2419-2425
    • (2000) Blood , vol.96 , pp. 2419-2425
    • Kottaridis, P.D.1    Milligan, D.W.2    Chopra, R.3
  • 27
    • 4444283753 scopus 로고    scopus 로고
    • Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzumab (FBC) conditioning
    • A.Y. Ho A. Pagliuca M. Kenyon et al. Reduced-intensity allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome and acute myeloid leukemia with multilineage dysplasia using fludarabine, busulphan, and alemtuzumab (FBC) conditioning Blood 104 2004 1616-1623
    • (2004) Blood , vol.104 , pp. 1616-1623
    • Ho, A.Y.1    Pagliuca, A.2    Kenyon, M.3
  • 28
    • 10344254167 scopus 로고    scopus 로고
    • Tacrolimus and mycophenolate mofetil for GVHD prevention after unrelated donor transplants
    • (abstr.)
    • P. McSweeney S. Abhyankar F. Petersen et al. Tacrolimus and mycophenolate mofetil for GVHD prevention after unrelated donor transplants Blood 102 2003 717a (abstr.)
    • (2003) Blood , vol.102
    • McSweeney, P.1    Abhyankar, S.2    Petersen, F.3
  • 29
    • 0142165064 scopus 로고    scopus 로고
    • Antithymocyteglobulin as prophylaxis of graft failure and graft-versus-host disease in recipients of partially T-cell-depleted grafts from matched unrelated donors: A dose-finding study
    • E. Meijer J.J. Cornelissen B. Lowenberg et al. Antithymocyteglobulin as prophylaxis of graft failure and graft-versus-host disease in recipients of partially T-cell-depleted grafts from matched unrelated donors: A dose-finding study Exp Hematol 31 2003 1026-1030
    • (2003) Exp. Hematol. , vol.31 , pp. 1026-1030
    • Meijer, E.1    Cornelissen, J.J.2    Lowenberg, B.3
  • 30
    • 4644341907 scopus 로고    scopus 로고
    • A phase I/II study of mycophenolate mofetil (MMF) in combination with cyclosporine (CSP) for prophylaxis of graft versus host disease (GVHD) after myeloablative conditioning and allogeneic hematopoietic stem cell transplantation (HCT): Dose escalation of MMF
    • (abstr)
    • R. Nash L. Johnston P. Parker et al. A phase I/II study of mycophenolate mofetil (MMF) in combination with cyclosporine (CSP) for prophylaxis of graft versus host disease (GVHD) after myeloablative conditioning and allogeneic hematopoietic stem cell transplantation (HCT): Dose escalation of MMF Blood 102 2003 240a (abstr)
    • (2003) Blood , vol.102
    • Nash, R.1    Johnston, L.2    Parker, P.3
  • 31
    • 0041941520 scopus 로고    scopus 로고
    • Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation
    • J.H. Antin H.T. Kim C. Cutler et al. Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation Blood 102 2003 1601-1605
    • (2003) Blood , vol.102 , pp. 1601-1605
    • Antin, J.H.1    Kim, H.T.2    Cutler, C.3
  • 32
    • 11144354152 scopus 로고    scopus 로고
    • Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation
    • C. Cutler H.T. Kim E. Hochberg et al. Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation Biol Blood Marrow Transplant 10 2004 328-336
    • (2004) Biol. Blood Marrow Transplant , vol.10 , pp. 328-336
    • Cutler, C.1    Kim, H.T.2    Hochberg, E.3
  • 33
    • 0025986570 scopus 로고
    • Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease
    • P.L. McCarthy Jr S. Abhyankar S. Neben et al. Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease Blood 78 1991 1915-1918
    • (1991) Blood , vol.78 , pp. 1915-1918
    • McCarthy Jr., P.L.1    Abhyankar, S.2    Neben, S.3
  • 34
    • 0037111657 scopus 로고    scopus 로고
    • Interleukin-1 blockade does not prevent acute graft-versus-host disease: Results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation
    • J.H. Antin D. Weisdorf D. Neuberg et al. Interleukin-1 blockade does not prevent acute graft-versus-host disease: Results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation Blood 100 2002 3479-3482
    • (2002) Blood , vol.100 , pp. 3479-3482
    • Antin, J.H.1    Weisdorf, D.2    Neuberg, D.3
  • 35
    • 3543088545 scopus 로고    scopus 로고
    • Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation
    • P.J. Martin J. Pei T. Gooley et al. Evaluation of a CD25-specific immunotoxin for prevention of graft-versus-host disease after unrelated marrow transplantation Biol Blood Marrow Transplant 10 2004 552-560
    • (2004) Biol. Blood Marrow Transplant , vol.10 , pp. 552-560
    • Martin, P.J.1    Pei, J.2    Gooley, T.3
  • 36
    • 0036682940 scopus 로고    scopus 로고
    • Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease
    • G. Gorgun K.B. Miller F.M. Foss Immunologic mechanisms of extracorporeal photochemotherapy in chronic graft-versus-host disease Blood 100 2002 941-947
    • (2002) Blood , vol.100 , pp. 941-947
    • Gorgun, G.1    Miller, K.B.2    Foss, F.M.3
  • 37
    • 0029945316 scopus 로고    scopus 로고
    • Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: A method to ameliorate graft-versus-host disease and extend the donor pool
    • J.G. Gribben E.C. Guinan V.A. Boussiotis et al. Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: A method to ameliorate graft-versus-host disease and extend the donor pool Blood 87 1996 4887-4893
    • (1996) Blood , vol.87 , pp. 4887-4893
    • Gribben, J.G.1    Guinan, E.C.2    Boussiotis, V.A.3
  • 38
    • 0033519661 scopus 로고    scopus 로고
    • Transplantation of anergic histoincompatible bone marrow allografts
    • E.C. Guinan V.A. Boussiotis D. Neuberg et al. Transplantation of anergic histoincompatible bone marrow allografts N Engl J Med 340 1999 1704-1714
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1704-1714
    • Guinan, E.C.1    Boussiotis, V.A.2    Neuberg, D.3
  • 39
    • 0036530011 scopus 로고    scopus 로고
    • Campath-1G causes rapid depletion of circulating host dendritic cells (DCs) before allogeneic transplantation but does not delay donor DC reconstitution
    • P. Klangsinsirikul G.I. Carter J.L. Byrne et al. Campath-1G causes rapid depletion of circulating host dendritic cells (DCs) before allogeneic transplantation but does not delay donor DC reconstitution Blood 99 2002 2586-2591
    • (2002) Blood , vol.99 , pp. 2586-2591
    • Klangsinsirikul, P.1    Carter, G.I.2    Byrne, J.L.3
  • 40
    • 19244365678 scopus 로고    scopus 로고
    • T-cell depletion with Campath-1H "in the bag" for matched related allogeneic peripheral blood stem cell transplantation is associated with reduced graft-versus-host disease, rapid immune constitution and improved survival
    • S. Chakrabarti D. MacDonald G. Hale et al. T-cell depletion with Campath-1H "in the bag" for matched related allogeneic peripheral blood stem cell transplantation is associated with reduced graft-versus-host disease, rapid immune constitution and improved survival Br J Haematol 121 2003 109-118
    • (2003) Br. J. Haematol. , vol.121 , pp. 109-118
    • Chakrabarti, S.1    MacDonald, D.2    Hale, G.3
  • 41
    • 0033214901 scopus 로고    scopus 로고
    • Risk of lymphoproliferative disorders after bone marrow transplantation: A multi-institutional study
    • R.E. Curtis L.B. Travis P.A. Rowlings et al. Risk of lymphoproliferative disorders after bone marrow transplantatio: A multi-institutional study Blood 94 1999 2208-2216
    • (1999) Blood , vol.94 , pp. 2208-2216
    • Curtis, R.E.1    Travis, L.B.2    Rowlings, P.A.3
  • 42
    • 17944375123 scopus 로고    scopus 로고
    • In vivo Campath-1H prevents GvHD following nonmyeloablative stem-cell transplantation
    • P.D. Kottaridis D.W. Milligan R. Chopra et al. In vivo Campath-1H prevents GvHD following nonmyeloablative stem-cell transplantation Cytotherapy 3 2001 197-201
    • (2001) Cytotherapy , vol.3 , pp. 197-201
    • Kottaridis, P.D.1    Milligan, D.W.2    Chopra, R.3
  • 43
    • 18744405985 scopus 로고    scopus 로고
    • Respiratory virus infections in transplant recipients after reduced-intensity conditioning with Campath-1H: High incidence but low mortality
    • S. Chakrabarti I. Avivi S. Mackinnon et al. Respiratory virus infections in transplant recipients after reduced-intensity conditioning with Campath-1H: High incidence but low mortality Br J Haematol 119 2002 1125-1132
    • (2002) Br. J. Haematol. , vol.119 , pp. 1125-1132
    • Chakrabarti, S.1    Avivi, I.2    Mackinnon, S.3
  • 44
    • 0037097836 scopus 로고    scopus 로고
    • High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: Potential role of Campath-1H in delaying immune reconstitution
    • S. Chakrabarti S. Mackinnon R. Chopra et al. High incidence of cytomegalovirus infection after nonmyeloablative stem cell transplantation: Potential role of Campath-1H in delaying immune reconstitution Blood 99 2002 4357-4363
    • (2002) Blood , vol.99 , pp. 4357-4363
    • Chakrabarti, S.1    Mackinnon, S.2    Chopra, R.3
  • 45
    • 0029918886 scopus 로고    scopus 로고
    • Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF)
    • A.C. Allison E.M. Eugui Purine metabolism and immunosuppressive effects of mycophenolate mofetil (MMF) Clin Transplant 10 1996 77-84
    • (1996) Clin. Transplant , vol.10 , pp. 77-84
    • Allison, A.C.1    Eugui, E.M.2
  • 46
    • 0033947957 scopus 로고    scopus 로고
    • Nonmyeloablative transplants: Preclinical and clinical results
    • B.M. Sandmaier P. McSweeney C. Yu et al. Nonmyeloablative transplants: preclinical and clinical results Semin Oncol 27 2000 78-81
    • (2000) Semin. Oncol. , vol.27 , pp. 78-81
    • Sandmaier, B.M.1    McSweeney, P.2    Yu, C.3
  • 47
    • 0344141613 scopus 로고    scopus 로고
    • Mycophenolate mofetil and cyclosporine as graft-versus-host disease prophylaxis after allogeneic blood stem cell transplantation
    • M. Bornhauser U. Schuler G. Porksen et al. Mycophenolate mofetil and cyclosporine as graft-versus-host disease prophylaxis after allogeneic blood stem cell transplantation Transplantation 67 1999 499-504
    • (1999) Transplantation , vol.67 , pp. 499-504
    • Bornhauser, M.1    Schuler, U.2    Porksen, G.3
  • 48
    • 10344225473 scopus 로고    scopus 로고
    • Favorable early transplant outcomes using tacrolimus and mycophenolate mofetil for GVHD prevention after matched sibling allografting
    • (abstr.)
    • P. McSweeney S. Abhyankar J. Foran et al. Favorable early transplant outcomes using tacrolimus and mycophenolate mofetil for GVHD prevention after matched sibling allografting Blood 102 2003 717a (abstr.)
    • (2003) Blood , vol.102
    • McSweeney, P.1    Abhyankar, S.2    Foran, J.3
  • 49
    • 0038299000 scopus 로고    scopus 로고
    • Sirolimus: Its discovery, biological properties, and mechanism of action
    • S.N. Sehgal Sirolimus: Its discovery, biological properties, and mechanism of action Transplant Proc 35 3 suppl 2003 7S-14S
    • (2003) Transplant Proc. , vol.35 , Issue.3 SUPPL.
    • Sehgal, S.N.1
  • 50
    • 0026068942 scopus 로고
    • Synergistic effect of the rapamycin-cyclosporine combination: Median effect analysis of in vitro immune performances by human T lymphocytes in PHA, CD3, and MLR proliferative and cytotoxicity assays
    • B.D. Kahan S. Gibbons N. Tejpal et al. Synergistic effect of the rapamycin-cyclosporine combination: Median effect analysis of in vitro immune performances by human T lymphocytes in PHA, CD3, and MLR proliferative and cytotoxicity assays Transplant Proc 23 1991 1090-1091
    • (1991) Transplant Proc. , vol.23 , pp. 1090-1091
    • Kahan, B.D.1    Gibbons, S.2    Tejpal, N.3
  • 51
    • 0022620989 scopus 로고
    • Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease. A prospective, randomized, double-blind trial
    • R.T. Mitsuyasu R.E. Champlin R.P. Gale et al. Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease. A prospective, randomized, double-blind trial Ann Intern Med 105 1986 20-26
    • (1986) Ann. Intern. Med. , vol.105 , pp. 20-26
    • Mitsuyasu, R.T.1    Champlin, R.E.2    Gale, R.P.3
  • 52
    • 0022495149 scopus 로고
    • Depletion of donor lymphocytes by counterflow centrifugation successfully prevents acute graft-versus-host disease in matched allogeneic marrow transplantation
    • T. de Witte J. Hoogenhout B. de Pauw et al. Depletion of donor lymphocytes by counterflow centrifugation successfully prevents acute graft-versus-host disease in matched allogeneic marrow transplantation Blood 67 1986 1302-1308
    • (1986) Blood , vol.67 , pp. 1302-1308
    • de Witte, T.1    Hoogenhout, J.2    de Pauw, B.3
  • 53
    • 0032571946 scopus 로고    scopus 로고
    • Tolerance induction by 'megadose' hematopoietic transplants: Donor-type human CD34 stem cells induce potent specific reduction of host anti-donor cytotoxic T lymphocyte precursors in mixed lymphocyte culture
    • M. Rachamim J. Gan H. Segall et al. Tolerance induction by 'megadose' hematopoietic transplants: Donor-type human CD34 stem cells induce potent specific reduction of host anti-donor cytotoxic T lymphocyte precursors in mixed lymphocyte culture Transplantation 65 1998 1386-1393
    • (1998) Transplantation , vol.65 , pp. 1386-1393
    • Rachamim, M.1    Gan, J.2    Segall, H.3
  • 54
    • 0242559250 scopus 로고    scopus 로고
    • Haploidentical stem cell transplantation for acute leukemia
    • F. Aversa A. Terenzi R. Felicini et al. Haploidentical stem cell transplantation for acute leukemia Int J Hematol 76 suppl 1 2002 165-168
    • (2002) Int. J. Hematol. , vol.76 , Issue.SUPPL. 1 , pp. 165-168
    • Aversa, F.1    Terenzi, A.2    Felicini, R.3
  • 55
    • 0033168770 scopus 로고    scopus 로고
    • Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation
    • L. Ruggeri M. Capanni M. Casucci et al. Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation Blood 94 1999 333-339
    • (1999) Blood , vol.94 , pp. 333-339
    • Ruggeri, L.1    Capanni, M.2    Casucci, M.3
  • 56
    • 0020839484 scopus 로고
    • Lethal graft-versus-host disease across minor histocompatibility barriers in mice
    • R. Korngold J. Sprent Lethal graft-versus-host disease across minor histocompatibility barriers in mice Clin Haematol 12 1983 681-693
    • (1983) Clin. Haematol. , vol.12 , pp. 681-693
    • Korngold, R.1    Sprent, J.2
  • 57
    • 1542456811 scopus 로고    scopus 로고
    • Impact of graft-versus-host disease (GVHD) prophylaxis on 3-year disease-free survival (DFS): Results of a multi-center, randomized phase II-III trial comparing T cell depletion/cyclosporine (TCD) and methotrexate/cyclosporine (M/C) in 410 recipients of unrelated donor bone marrow
    • (abstr.)
    • J. Wagner J. Thompson S. Carter et al. Impact of graft-versus-host disease (GVHD) prophylaxis on 3-year disease-free survival (DFS): results of a multi-center, randomized phase II-III trial comparing T cell depletion/cyclosporine (TCD) and methotrexate/cyclosporine (M/C) in 410 recipients of unrelated donor bone marrow Blood 100 2002 75a (abstr.)
    • (2002) Blood , vol.100
    • Wagner, J.1    Thompson, J.2    Carter, S.3
  • 58
    • 85047698374 scopus 로고    scopus 로고
    • Association between pretransplant Thymoglobulin and reduced non-relapse mortality rate after marrow transplantation from unrelated donors
    • M. Remberger B. Storer O. Ringden et al. Association between pretransplant Thymoglobulin and reduced non-relapse mortality rate after marrow transplantation from unrelated donors Bone Marrow Transplant 29 2002 391-397
    • (2002) Bone Marrow Transplant , vol.29 , pp. 391-397
    • Remberger, M.1    Storer, B.2    Ringden, O.3
  • 59
    • 0036861875 scopus 로고    scopus 로고
    • Unrelated donor BMT recipients given pretransplant low-dose antithymocyte globulin have outcomes equivalent to matched sibling BMT: A matched pair analysis
    • P. Duggan K. Booth A. Chaudhry et al. Unrelated donor BMT recipients given pretransplant low-dose antithymocyte globulin have outcomes equivalent to matched sibling BMT: A matched pair analysis Bone Marrow Transplant 30 2002 681-686
    • (2002) Bone Marrow Transplant , vol.30 , pp. 681-686
    • Duggan, P.1    Booth, K.2    Chaudhry, A.3
  • 60
    • 0035892107 scopus 로고    scopus 로고
    • Antithymocyte globulin for graft-versus-host disease prophylaxis in transplants from unrelated donors: 2 randomized studies from Gruppo Italiano Trapianti Midollo Osseo (GITMO)
    • A. Bacigalupo T. Lamparelli P. Bruzzi et al. Antithymocyte globulin for graft-versus-host disease prophylaxis in transplants from unrelated donors: 2 randomized studies from Gruppo Italiano Trapianti Midollo Osseo (GITMO) Blood 98 2001 2942-2947
    • (2001) Blood , vol.98 , pp. 2942-2947
    • Bacigalupo, A.1    Lamparelli, T.2    Bruzzi, P.3
  • 61
    • 0032055354 scopus 로고    scopus 로고
    • Induction of Fas (Apo-1, CD95)-mediated apoptosis of activated lymphocytes by polyclonal antithymocyte globulins
    • L. Genestier S. Fournel M. Flacher et al. Induction of Fas (Apo-1, CD95)-mediated apoptosis of activated lymphocytes by polyclonal antithymocyte globulins Blood 91 1998 2360-2368
    • (1998) Blood , vol.91 , pp. 2360-2368
    • Genestier, L.1    Fournel, S.2    Flacher, M.3
  • 62
    • 0036048349 scopus 로고    scopus 로고
    • Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: Comparison of grading systems
    • M.L. MacMillan D.J. Weisdorf J.E. Wagner et al. Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems Biol Blood Marrow Transplant 8 2002 387-394
    • (2002) Biol. Blood Marrow Transplant , vol.8 , pp. 387-394
    • MacMillan, M.L.1    Weisdorf, D.J.2    Wagner, J.E.3
  • 63
    • 4143083807 scopus 로고    scopus 로고
    • Extracorporeal photopheresis in graft-versus-host disease: T cell senescence in vivo
    • S. Lee B. Dorken C.A. Schmitt Extracorporeal photopheresis in graft-versus-host disease ultraviolet radiation mediates: T cell senescence in vivo Transplantation 78 2004 484-485
    • (2004) Transplantation , vol.78 , pp. 484-485
    • Lee, S.1    Dorken, B.2    Schmitt, C.A.3
  • 64
    • 10344249263 scopus 로고    scopus 로고
    • Phase I/II trial on the use of etanercept (Enbrel) and soluMedrol as primary treatment for acute graft-vs-host disease (aGVHD)
    • [abstr.]
    • J. Uberti L. Ayash J. Levine et al. Phase I/II trial on the use of etanercept (Enbrel) and soluMedrol as primary treatment for acute graft-vs-host disease (aGVHD) Blood 102 2003 243a [abstr.]
    • (2003) Blood , vol.102
    • Uberti, J.1    Ayash, L.2    Levine, J.3
  • 65
    • 3242756749 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha blockade for the treatment of acute GVHD
    • D. Couriel R. Saliba K. Hicks et al. Tumor necrosis factor-alpha blockade for the treatment of acute GVHD Blood 104 2004 649-654
    • (2004) Blood , vol.104 , pp. 649-654
    • Couriel, D.1    Saliba, R.2    Hicks, K.3
  • 66
    • 3843103590 scopus 로고    scopus 로고
    • Safety and efficacy of denileukin diftitox in patients with steroid refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
    • V.T. Ho D. Zahrieh E. Hochberg et al. Safety and efficacy of denileukin diftitox in patients with steroid refractory acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation Blood 104 2004 1224-1226
    • (2004) Blood , vol.104 , pp. 1224-1226
    • Ho, V.T.1    Zahrieh, D.2    Hochberg, E.3
  • 67
    • 0042073514 scopus 로고    scopus 로고
    • Pentostatin in steroid refractory acute graft versus host disease
    • (abstr.)
    • J. Bolanos-Meade D. Jacobson J. Margolis et al. Pentostatin in steroid refractory acute graft versus host disease Blood 100 2002 420a (abstr.)
    • (2002) Blood , vol.100
    • Bolanos-Meade, J.1    Jacobson, D.2    Margolis, J.3
  • 68
    • 4444304402 scopus 로고    scopus 로고
    • Effect of up-front daclizumab when combined with steroids for the treatment of acute graft-versus-host disease: Results of a randomized trial
    • S.J. Lee D. Zahrieh E. Agura et al. Effect of up-front daclizumab when combined with steroids for the treatment of acute graft-versus-host disease: Results of a randomized trial Blood 104 2004 1559-1564
    • (2004) Blood , vol.104 , pp. 1559-1564
    • Lee, S.J.1    Zahrieh, D.2    Agura, E.3
  • 69
    • 17844362706 scopus 로고    scopus 로고
    • Treatment of steroid-resistant acute graft-versus-host disease with anti-thymocyte globulin
    • H. Khoury A. Kashyap D.R. Adkins et al. Treatment of steroid-resistant acute graft-versus-host disease with anti-thymocyte globulin Bone Marrow Transplant 27 2001 1059-1064
    • (2001) Bone Marrow Transplant , vol.27 , pp. 1059-1064
    • Khoury, H.1    Kashyap, A.2    Adkins, D.R.3
  • 70
    • 0036210985 scopus 로고    scopus 로고
    • Poor outcome in steroid-refractory graft-versus-host disease with antithymocyte globulin treatment
    • S. Arai J. Margolis M. Zahurak et al. Poor outcome in steroid-refractory graft-versus-host disease with antithymocyte globulin treatment Biol Blood Marrow Transplant 8 2002 155-160
    • (2002) Biol. Blood Marrow Transplant , vol.8 , pp. 155-160
    • Arai, S.1    Margolis, J.2    Zahurak, M.3
  • 71
    • 79960971433 scopus 로고    scopus 로고
    • Pentostatin: A promising treatment for refractory chronic GVHD
    • (abstr.)
    • D. Jacobsohn J. Margolis A. Chen et al. Pentostatin: A promising treatment for refractory chronic GVHD Blood 98 2001 399a (abstr.)
    • (2001) Blood , vol.98
    • Jacobsohn, D.1    Margolis, J.2    Chen, A.3
  • 72
    • 0038309967 scopus 로고    scopus 로고
    • Pentostatin for the treatment of chronic graft-versus-host disease in children
    • J.D. Goldberg D.A. Jacobsohn J. Margolis et al. Pentostatin for the treatment of chronic graft-versus-host disease in children J Pediatr Hematol Oncol 25 2003 584-588
    • (2003) J. Pediatr. Hematol. Oncol. , vol.25 , pp. 584-588
    • Goldberg, J.D.1    Jacobsohn, D.A.2    Margolis, J.3
  • 73
    • 0034307671 scopus 로고    scopus 로고
    • Extracorporeal photochemotherapy in the treatment of severe steroid-refractory acute graft-versus-host disease: A pilot study
    • H.T. Greinix B. Volc-Platzer P. Kalhs et al. Extracorporeal photochemotherapy in the treatment of severe steroid-refractory acute graft-versus-host disease: A pilot study Blood 96 2000 2426-2431
    • (2000) Blood , vol.96 , pp. 2426-2431
    • Greinix, H.T.1    Volc-Platzer, B.2    Kalhs, P.3
  • 74
    • 0036673250 scopus 로고    scopus 로고
    • Extracorporeal photochemotherapy for the treatment of graft-versus-host disease
    • R. Dall'Amico C. Messina Extracorporeal photochemotherapy for the treatment of graft-versus-host disease Ther Apher 6 2002 296-304
    • (2002) Ther. Apher. , vol.6 , pp. 296-304
    • Dall'Amico, R.1    Messina, C.2
  • 75
    • 0042740515 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
    • K. Le Blanc L. Tammik B. Sundberg et al. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex Scand J Immunol 57 2003 11-20
    • (2003) Scand. J. Immunol. , vol.57 , pp. 11-20
    • Le Blanc, K.1    Tammik, L.2    Sundberg, B.3
  • 76
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • K. Le Blanc I. Rasmusson B. Sundberg et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells Lancet 363 2004 1439-1441
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3


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