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Volumn 42, Issue 12, 2004, Pages 719-723

A new simple diagnostic for the identification of the major CYP2D6 genotypes by DNA sequencing analysis

Author keywords

Cytochrome P450 (CYP)2D6; Genotype; Pharmacogenetics; Polymorphism

Indexed keywords

CYTOCHROME P450 2D6;

EID: 10344245504     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: 10.5414/CPP42719     Document Type: Article
Times cited : (19)

References (18)
  • 1
    • 0031960328 scopus 로고    scopus 로고
    • Ultrarapid metabolism of sparteine: Frequency of alleles with duplicated CYP2D6 genes in a Danish population as determined by restriction fragment length polymorphism and long polymerase chain reaction
    • Bathum L, Johansson I, Ingelman-Sundberg M, Høorder M, Brøsen K 1998 Ultrarapid metabolism of sparteine: frequency of alleles with duplicated CYP2D6 genes in a Danish population as determined by restriction fragment length polymorphism and long polymerase chain reaction. Pharmacogenetics 8: 119-123
    • (1998) Pharmacogenetics , vol.8 , pp. 119-123
    • Bathum, L.1    Johansson, I.2    Ingelman-Sundberg, M.3    Høorder, M.4    Brøsen, K.5
  • 2
    • 0029028932 scopus 로고
    • Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19
    • Bertilsson L 1995 Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. Clin Pharmacokinet 29: 192-209
    • (1995) Clin. Pharmacokinet. , vol.29 , pp. 192-209
    • Bertilsson, L.1
  • 3
    • 10344253928 scopus 로고    scopus 로고
    • CYP2D6 "Intermediate metabolizer" phenotype as a consequence of genetically determined alternative splicing
    • Chem Listy, Symposia, 97, Abstract TP41, S137
    • Cesaro C, Raimundo S, Klein K, Schäffeler E, Eichelbaum M, Schwab M, Zanger UM 2003 CYP2D6 "Intermediate metabolizer" phenotype as a consequence of genetically determined alternative splicing. Chem Listy, Symposia, 97, Abstract TP41, S137
    • (2003)
    • Cesaro, C.1    Raimundo, S.2    Klein, K.3    Schäffeler, E.4    Eichelbaum, M.5    Schwab, M.6    Zanger, U.M.7
  • 5
    • 0035775486 scopus 로고    scopus 로고
    • Pharmacogenomics: The inherited basis for interindividual differences in drug response
    • Evans WE, Johnson JA 2001 Pharmacogenomics: the inherited basis for interindividual differences in drug response. Annu Rev Genomics Hum Genet 2: 9-39
    • (2001) Annu. Rev. Genomics Hum. Genet. , vol.2 , pp. 9-39
    • Evans, W.E.1    Johnson, J.A.2
  • 7
    • 0025080352 scopus 로고
    • Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification
    • Heim M, Meyer UA 1990 Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification. Lancet 336: 529-532
    • (1990) Lancet , vol.336 , pp. 529-532
    • Heim, M.1    Meyer, U.A.2
  • 9
    • 0028997955 scopus 로고
    • "It's the genes, stupid": Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism
    • Krömer HK, Eichelbaum M 1995 "It's the genes, stupid": molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism. Life Sci 56: 2285-2298
    • (1995) Life Sci. , vol.56 , pp. 2285-2298
    • Krömer, H.K.1    Eichelbaum, M.2
  • 10
    • 0033590590 scopus 로고    scopus 로고
    • Genetic mechanisms for duplication and multiplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes
    • Lundqvist E, Johansson I, Ingelman-Sundberg M 1999 Genetic mechanisms for duplication and multiplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes. Gene 226 327-338
    • (1999) Gene , vol.226 , pp. 327-338
    • Lundqvist, E.1    Johansson, I.2    Ingelman-Sundberg, M.3
  • 11
    • 0028826569 scopus 로고
    • A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype
    • Marez D, Sabbagh N, Legrand M, Lo-Guidice JM, Boone P, Broly F 1995 A novel CYP2D6 allele with an abolished splice recognition site associated with the poor metabolizer phenotype. Pharmacogenetics 5: 305-311
    • (1995) Pharmacogenetics , vol.5 , pp. 305-311
    • Marez, D.1    Sabbagh, N.2    Legrand, M.3    Lo-Guidice, J.M.4    Boone, P.5    Broly, F.6
  • 12
    • 0030860004 scopus 로고    scopus 로고
    • Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: Characterization of 48 mutations and 53 alleles, their frequencies and evolution
    • Marez D, Legrand M, Sabbagh N, Lo-Guidice JM, Spire C, Lafitte J-J, Meyer UA, Broly F 1997 Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution. Pharmacogenetics 7: 193-202
    • (1997) Pharmacogenetics , vol.7 , pp. 193-202
    • Marez, D.1    Legrand, M.2    Sabbagh, N.3    Lo-Guidice, J.M.4    Spire, C.5    Lafitte, J.-J.6    Meyer, U.A.7    Broly, F.8
  • 14
    • 0036041454 scopus 로고    scopus 로고
    • Pharmacokinetics of the antianginal agent perhexiline: Relationship between metabolic ratio and steady-state dose
    • Sallustio BC, Westley IS, Morris RG 2002 Pharmacokinetics of the antianginal agent perhexiline: relationship between metabolic ratio and steady-state dose. Br J Clin Pharmacol 54 107-114
    • (2002) Br. J. Clin. Pharmacol. , vol.54 , pp. 107-114
    • Sallustio, B.C.1    Westley, I.S.2    Morris, R.G.3
  • 15
    • 0036720991 scopus 로고    scopus 로고
    • Rapid and reliable method for cytochrome P450 2D6 genotyping
    • Stamer UM, Bayerer B, Wolf S, Hoeft A, Stuber F 2002 Rapid and reliable method for cytochrome P450 2D6 genotyping. Clin Chem 48: 1412-1417
    • (2002) Clin. Chem. , vol.48 , pp. 1412-1417
    • Stamer, U.M.1    Bayerer, B.2    Wolf, S.3    Hoeft, A.4    Stuber, F.5
  • 16
    • 0029846193 scopus 로고    scopus 로고
    • Rapid detection of CYP2D6 null alleles by long distance- and multiplex-polymerase chain reaction
    • Stüven T, Griese EU, Krömer HK, Eichelbaum M, Zanger UM 1996 Rapid detection of CYP2D6 null alleles by long distance- and multiplex-polymerase chain reaction. Pharmacogenetics 6: 417-421
    • (1996) Pharmacogenetics , vol.6 , pp. 417-421
    • Stüven, T.1    Griese, E.U.2    Krömer, H.K.3    Eichelbaum, M.4    Zanger, U.M.5
  • 17
    • 0242637084 scopus 로고    scopus 로고
    • Identification of CYP2D6 alleles by single nucleotide polymorphism analysis using pyrosequencing
    • Zackrisson AL, Lindblom B 2003 Identification of CYP2D6 alleles by single nucleotide polymorphism analysis using pyrosequencing. Eur J Clin Pharmacol 59: 521-526
    • (2003) Eur. J. Clin. Pharmacol. , vol.59 , pp. 521-526
    • Zackrisson, A.L.1    Lindblom, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.