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Volumn 71, Issue 6, 2004, Pages 811-821

Genetically modified, live attenuated dengue virus type 3 vaccine candidates

Author keywords

[No Author keywords available]

Indexed keywords

DEN3 VACCINE; DENGUE VACCINE; LIVE VACCINE; UNCLASSIFIED DRUG;

EID: 10144222415     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2004.71.811     Document Type: Article
Times cited : (100)

References (47)
  • 1
    • 0001424128 scopus 로고    scopus 로고
    • Flaviviridae: The viruses and their replication
    • Fields BN, Knipe DM, Howley PM, Chanock RM, Melnick JL, Monath TP, Roizman B, Straus SE, eds. Philadelphia: Lippincott-Raven Publishers
    • Rice CM, 1996. Flaviviridae: the viruses and their replication. Fields BN, Knipe DM, Howley PM, Chanock RM, Melnick JL, Monath TP, Roizman B, Straus SE, eds. Fields Virology. Philadelphia: Lippincott-Raven Publishers, 931-959.
    • (1996) Fields Virology , pp. 931-959
    • Rice, C.M.1
  • 2
    • 0000445568 scopus 로고    scopus 로고
    • Molecular biology of dengue viruses
    • Gubler DJ, Kuno G, eds. New York: CAB International
    • Chang G-J, 1997. Molecular biology of dengue viruses. Gubler DJ, Kuno G, eds. Dengue and Dengue Hemorrhagic Fever. New York: CAB International, 175-198.
    • (1997) Dengue and Dengue Hemorrhagic Fever , pp. 175-198
    • Chang, G.-J.1
  • 3
    • 0031823546 scopus 로고    scopus 로고
    • Dengue and dengue hemorrhagic fever
    • Gubler DJ, 1998. Dengue and dengue hemorrhagic fever. Clin Microbiol Rev 11: 480-496.
    • (1998) Clin Microbiol Rev , vol.11 , pp. 480-496
    • Gubler, D.J.1
  • 4
    • 0033258362 scopus 로고    scopus 로고
    • Impact of dengue/dengue hemorrhagic fever on the developing world
    • Gubler DJ, Meltzer M, 1999. Impact of dengue/dengue hemorrhagic fever on the developing world. Adv Virus Res 53: 35-70.
    • (1999) Adv Virus Res , vol.53 , pp. 35-70
    • Gubler, D.J.1    Meltzer, M.2
  • 5
    • 0001955284 scopus 로고
    • Dengue and dengue hemorrhagic fever
    • Porter-field JS, ed. London: Chapman and Hall
    • Innis BL, 1995. Dengue and dengue hemorrhagic fever. Porter-field JS, ed. Exotic Viral Infections. London: Chapman and Hall, 103-146.
    • (1995) Exotic Viral Infections , pp. 103-146
    • Innis, B.L.1
  • 6
    • 0037135664 scopus 로고    scopus 로고
    • Accelerating the development and introduction of a dengue vaccine for poor children, 5-8 December, 2001, Ho Chi Minh City, Vietnam
    • Almond J, Clemens J, Engers H, Halstead S, Khiem HB, Pablos-Mendez A, Pervikov Y, Tram T, 2002. Accelerating the development and introduction of a dengue vaccine for poor children, 5-8 December, 2001, Ho Chi Minh City, Vietnam. Vaccine 20: 3043-3046.
    • (2002) Vaccine , vol.20 , pp. 3043-3046
    • Almond, J.1    Clemens, J.2    Engers, H.3    Halstead, S.4    Khiem, H.B.5    Pablos-Mendez, A.6    Pervikov, Y.7    Tram, T.8
  • 7
    • 0000337563 scopus 로고    scopus 로고
    • Yellow fever
    • Plotkin SA, Orenstein WA, eds. Philadelphia: W.B. Saunders Co.
    • Monath TP, 1999. Yellow fever. Plotkin SA, Orenstein WA, eds. Vaccines. Philadelphia: W.B. Saunders Co., 815-879.
    • (1999) Vaccines , pp. 815-879
    • Monath, T.P.1
  • 9
    • 0037408183 scopus 로고    scopus 로고
    • Dengue and dengue hemorrhagic fever in the Americas: Lessons and challenges
    • Guzman MG, Kouri G, 2003. Dengue and dengue hemorrhagic fever in the Americas: lessons and challenges. J Clin Virol 27: 1-13.
    • (2003) J Clin Virol , vol.27 , pp. 1-13
    • Guzman, M.G.1    Kouri, G.2
  • 12
    • 0023818748 scopus 로고
    • Pathogenesis of dengue: Challenges to molecular biology
    • Halstead SB, 1988. Pathogenesis of dengue: challenges to molecular biology. Science 239: 476-481.
    • (1988) Science , vol.239 , pp. 476-481
    • Halstead, S.B.1
  • 13
    • 1342331446 scopus 로고    scopus 로고
    • Modification of dengue virus strains by passage in primary dog kidney cells: Preparation of candidate vaccines and immunization of monkeys
    • Eckels KH, Dubois DR, Putnak R, Vaughn DW, Innis BL, Henchal EA, Hoke CH Jr, 2003. Modification of dengue virus strains by passage in primary dog kidney cells: preparation of candidate vaccines and immunization of monkeys. Am J Trop Med Hyg 69: 12-16.
    • (2003) Am J Trop Med Hyg , vol.69 , pp. 12-16
    • Eckels, K.H.1    Dubois, D.R.2    Putnak, R.3    Vaughn, D.W.4    Innis, B.L.5    Henchal, E.A.6    Hoke Jr., C.H.7
  • 18
    • 0036304311 scopus 로고    scopus 로고
    • Viremia and immunogenicity in nonhuman primates of a tetravalent yellow fever-dengue chimeric vaccine: Genetic reconstructions, dose adjustment, and antibody responses against wild-type dengue virus isolates
    • Guirakhoo F, Pugachev K, Arroyo J, Miller C, Zhang ZX, Weltzin R, Georgakopoulos K, Catalan J. Ocran S, Draper K, Monath TP. 2002. Viremia and immunogenicity in nonhuman primates of a tetravalent yellow fever-dengue chimeric vaccine: genetic reconstructions, dose adjustment, and antibody responses against wild-type dengue virus isolates. Virology 298: 146-159.
    • (2002) Virology , vol.298 , pp. 146-159
    • Guirakhoo, F.1    Pugachev, K.2    Arroyo, J.3    Miller, C.4    Zhang, Z.X.5    Weltzin, R.6    Georgakopoulos, K.7    Catalan, J.8    Ocran, S.9    Draper, K.10    Monath, T.P.11
  • 21
    • 0037223896 scopus 로고    scopus 로고
    • A live, attenuated dengue virus type 1 vaccine candidate with a 30-nucleotide deletion in the 3′ untranslated region is highly attenuated and immunogenic in monkeys
    • Whitehead SS, Falgout B, Hanley KA, Blaney JE Jr, Markoff L, Murphy BR, 2003. A live, attenuated dengue virus type 1 vaccine candidate with a 30-nucleotide deletion in the 3′ untranslated region is highly attenuated and immunogenic in monkeys. J Virol 77: 1653-1657.
    • (2003) J Virol , vol.77 , pp. 1653-1657
    • Whitehead, S.S.1    Falgout, B.2    Hanley, K.A.3    Blaney Jr., J.E.4    Markoff, L.5    Murphy, B.R.6
  • 22
    • 0346817393 scopus 로고    scopus 로고
    • Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys
    • Whitehead SS, Hanley KA, Blaney JE, Gilmore LE, Elkins WK, Murphy BR, 2003. Substitution of the structural genes of dengue virus type 4 with those of type 2 results in chimeric vaccine candidates which are attenuated for mosquitoes, mice, and rhesus monkeys. Vaccine 21: 4307-4316.
    • (2003) Vaccine , vol.21 , pp. 4307-4316
    • Whitehead, S.S.1    Hanley, K.A.2    Blaney, J.E.3    Gilmore, L.E.4    Elkins, W.K.5    Murphy, B.R.6
  • 23
    • 0036140438 scopus 로고    scopus 로고
    • Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes
    • Hanley KA, Lee JJ, Blaney JE Jr, Murphy BR, Whitehead SS, 2002. Paired charge-to-alanine mutagenesis of dengue virus type 4 NS5 generates mutants with temperature-sensitive, host range, and mouse attenuation phenotypes. J Virol 76: 525-531.
    • (2002) J Virol , vol.76 , pp. 525-531
    • Hanley, K.A.1    Lee, J.J.2    Blaney Jr., J.E.3    Murphy, B.R.4    Whitehead, S.S.5
  • 24
    • 0034801795 scopus 로고    scopus 로고
    • Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in Vero cells or human liver cells and attenuated in mice
    • Blaney JE Jr, Johnson DH, Firestone CY, Hanson CT, Murphy BR, Whitehead SS, 2001. Chemical mutagenesis of dengue virus type 4 yields mutant viruses which are temperature sensitive in Vero cells or human liver cells and attenuated in mice, J Virol 75: 9731-9740.
    • (2001) J Virol , vol.75 , pp. 9731-9740
    • Blaney Jr., J.E.1    Johnson, D.H.2    Firestone, C.Y.3    Hanson, C.T.4    Murphy, B.R.5    Whitehead, S.S.6
  • 25
    • 0038394486 scopus 로고    scopus 로고
    • Temperature sensitive mutations in the genes encoding the NS1, NS2A, NS3, and NS5 nonstructural proteins of dengue virus type 4 restrict replication in the brains of mice
    • Blaney JE Jr, Manipon GG, Murphy BR, Whitehead SS, 2003. Temperature sensitive mutations in the genes encoding the NS1, NS2A, NS3, and NS5 nonstructural proteins of dengue virus type 4 restrict replication in the brains of mice. Arch Virol 148: 999-1006.
    • (2003) Arch Virol , vol.148 , pp. 999-1006
    • Blaney Jr., J.E.1    Manipon, G.G.2    Murphy, B.R.3    Whitehead, S.S.4
  • 26
    • 0036383047 scopus 로고    scopus 로고
    • Genetic basis of attenuation of dengue virus type 4 small plaque mutants with restricted replication in suckling mice and in SCID mice transplanted with human liver cells
    • Blaney JE Jr, Johnson DH, Manipon GG, Firestone CY, Hanson CT, Murphy BR, Whitehead SS, 2002. Genetic basis of attenuation of dengue virus type 4 small plaque mutants with restricted replication in suckling mice and in SCID mice transplanted with human liver cells. Virology 300: 125-139.
    • (2002) Virology , vol.300 , pp. 125-139
    • Blaney Jr., J.E.1    Johnson, D.H.2    Manipon, G.G.3    Firestone, C.Y.4    Hanson, C.T.5    Murphy, B.R.6    Whitehead, S.S.7
  • 27
    • 4043141495 scopus 로고    scopus 로고
    • Introduction of mutations into the non-structural genes or 3′ untranslated region of an attenuated dengue virus type 4 vaccine candidate further decreases replication in rhesus monkeys while retaining protective immunity
    • Hanley KA, Manlucu LR, Manipon GG, Hanson CT, Whitehead SS, Murphy BR, Blaney JE Jr, 2004. Introduction of mutations into the non-structural genes or 3′ untranslated region of an attenuated dengue virus type 4 vaccine candidate further decreases replication in rhesus monkeys while retaining protective immunity. Vaccine 22: 3440-3448.
    • (2004) Vaccine , vol.22 , pp. 3440-3448
    • Hanley, K.A.1    Manlucu, L.R.2    Manipon, G.G.3    Hanson, C.T.4    Whitehead, S.S.5    Murphy, B.R.6    Blaney Jr., J.E.7
  • 28
    • 0043169616 scopus 로고    scopus 로고
    • A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4
    • Hanley KA, Manlucu LR, Gilmore LE, Blaney JE Jr, Hanson CT, Murphy BR, Whitehead SS, 2003. A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4. Virology 312: 222-232.
    • (2003) Virology , vol.312 , pp. 222-232
    • Hanley, K.A.1    Manlucu, L.R.2    Gilmore, L.E.3    Blaney Jr., J.E.4    Hanson, C.T.5    Murphy, B.R.6    Whitehead, S.S.7
  • 29
  • 30
    • 0019966544 scopus 로고
    • Growth of human hepatoma cells lines with differentiated functions in chemically defined medium
    • Nakabayashi H, Taketa K, Miyano K, Yamane T, Sato J, 1982. Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Res 42: 3858-3863.
    • (1982) Cancer Res , vol.42 , pp. 3858-3863
    • Nakabayashi, H.1    Taketa, K.2    Miyano, K.3    Yamane, T.4    Sato, J.5
  • 31
    • 0026012318 scopus 로고
    • Infectious RNA transcribed from stably cloned full-length cDNA of dengue type 4 virus
    • Lai CJ, Zhao BT, Hori H, Bray M, 1991. Infectious RNA transcribed from stably cloned full-length cDNA of dengue type 4 virus. Proc Natl Acad Sci USA 88: 5139-5143.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5139-5143
    • Lai, C.J.1    Zhao, B.T.2    Hori, H.3    Bray, M.4
  • 32
    • 0029893436 scopus 로고    scopus 로고
    • Dengue type 4 virus mutants containing deletions in the 3′ noncoding region of the RNA genome: Analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys
    • Men R, Bray M, Clark D, Chanock RM, Lai CJ, 1996. Dengue type 4 virus mutants containing deletions in the 3′ noncoding region of the RNA genome: analysis of growth restriction in cell culture and altered viremia pattern and immunogenicity in rhesus monkeys. J Virol 70: 3930-3937.
    • (1996) J Virol , vol.70 , pp. 3930-3937
    • Men, R.1    Bray, M.2    Clark, D.3    Chanock, R.M.4    Lai, C.J.5
  • 33
    • 0035215425 scopus 로고    scopus 로고
    • A live attenuated recombinant dengue-4 virus vaccine candidate with restricted capacity for dissemination in mosquitoes and lack of transmission from vaccinees to mosquitoes
    • Troyer JM, Hanley KA, Whitehead SS, Strickman D, Karron RA, Durbin AP, Murphy BR, 2001. A live attenuated recombinant dengue-4 virus vaccine candidate with restricted capacity for dissemination in mosquitoes and lack of transmission from vaccinees to mosquitoes. Am J Trop Med Hyg 65: 414-419.
    • (2001) Am J Trop Med Hyg , vol.65 , pp. 414-419
    • Troyer, J.M.1    Hanley, K.A.2    Whitehead, S.S.3    Strickman, D.4    Karron, R.A.5    Durbin, A.P.6    Murphy, B.R.7
  • 34
    • 33745158157 scopus 로고
    • A simple method of estimating fifty percent endpoints
    • Reed LJ, Muench H, 1938. A simple method of estimating fifty percent endpoints. Am J Hyg 27: 493-497.
    • (1938) Am J Hyg , vol.27 , pp. 493-497
    • Reed, L.J.1    Muench, H.2
  • 35
    • 0037022604 scopus 로고    scopus 로고
    • West Nile virus/dengue type 4 virus chimeras that are reduced in neurovirulence and peripheral virulence without loss of immunogenicity or protective efficacy
    • Pletnev AG, Putnak R, Speicher J, Wagar EJ, Vaughn DW, 2002. West Nile virus/dengue type 4 virus chimeras that are reduced in neurovirulence and peripheral virulence without loss of immunogenicity or protective efficacy. Proc Natl Acad Sci USA 99: 3036-3041.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3036-3041
    • Pletnev, A.G.1    Putnak, R.2    Speicher, J.3    Wagar, E.J.4    Vaughn, D.W.5
  • 36
    • 0026473001 scopus 로고
    • Construction and characterization of chimeric tick-borne encephalitis/dengue type 4 viruses
    • Pletnev AG, Bray M, Muggins J, Lai CJ, 1992. Construction and characterization of chimeric tick-borne encephalitis/dengue type 4 viruses. Proc Natl Acad Sci USA 89: 10532-10536.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 10532-10536
    • Pletnev, A.G.1    Bray, M.2    Muggins, J.3    Lai, C.J.4
  • 37
    • 0346186973 scopus 로고    scopus 로고
    • Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells
    • Blaney JE, Manipon GG, Firestone CY, Johnson DH, Hanson CT, Murphy BR, Whitehead SS, 2003. Mutations which enhance the replication of dengue virus type 4 and an antigenic chimeric dengue virus type 2/4 vaccine candidate in Vero cells. Vaccine 21: 4317-4327.
    • (2003) Vaccine , vol.21 , pp. 4317-4327
    • Blaney, J.E.1    Manipon, G.G.2    Firestone, C.Y.3    Johnson, D.H.4    Hanson, C.T.5    Murphy, B.R.6    Whitehead, S.S.7
  • 40
    • 0141680269 scopus 로고    scopus 로고
    • Molecularly engineered live-attenuated chimeric West Nile/dengue virus vaccines protect rhesus monkeys from West Nile virus
    • Pletnev AG, Claire MS, Elkins R, Speicher J, Murphy BR, Chanock RM, 2003. Molecularly engineered live-attenuated chimeric West Nile/dengue virus vaccines protect rhesus monkeys from West Nile virus. Virology 314: 190-195.
    • (2003) Virology , vol.314 , pp. 190-195
    • Pletnev, A.G.1    Claire, M.S.2    Elkins, R.3    Speicher, J.4    Murphy, B.R.5    Chanock, R.M.6
  • 41
    • 0029042305 scopus 로고
    • Construction of intertypic chimeric dengue viruses exhibiting type 3 antigenicity and neurovirulence for mice
    • Chen W, Kawano H, Men R, Clark D, Lai CJ, 1995. Construction of intertypic chimeric dengue viruses exhibiting type 3 antigenicity and neurovirulence for mice. J Virol 69: 5186-5190.
    • (1995) J Virol , vol.69 , pp. 5186-5190
    • Chen, W.1    Kawano, H.2    Men, R.3    Clark, D.4    Lai, C.J.5
  • 43
    • 0000902443 scopus 로고
    • History of Sabin attenuated poliovirus oral live vaccine strains
    • Sabin A, Boulger L, 1973. History of Sabin attenuated poliovirus oral live vaccine strains. J Biol Stand 1: 115-118.
    • (1973) J Biol Stand , vol.1 , pp. 115-118
    • Sabin, A.1    Boulger, L.2
  • 44
    • 0000708194 scopus 로고    scopus 로고
    • Immunization against viral diseases
    • Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Strauss SE, eds. Philadelphia: Lippincott Williams & Wilkins
    • Murphy BR, Chanock RM, 2001. Immunization against viral diseases. Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Strauss SE, eds. Fields Virology. Philadelphia: Lippincott Williams & Wilkins, 435-468.
    • (2001) Fields Virology , pp. 435-468
    • Murphy, B.R.1    Chanock, R.M.2
  • 45
    • 0030746980 scopus 로고    scopus 로고
    • Secondary structure of the 3' untranslated region of flaviviruses: Similarities and differences
    • Proutski V, Gould EA, Holmes EC, 1997. Secondary structure of the 3' untranslated region of flaviviruses: similarities and differences. Nucleic Acids Res 25: 1194-1202.
    • (1997) Nucleic Acids Res , vol.25 , pp. 1194-1202
    • Proutski, V.1    Gould, E.A.2    Holmes, E.C.3
  • 47
    • 0033594983 scopus 로고    scopus 로고
    • Widespread intra-serotype recombination in natural populations of dengue virus
    • Worobey M, Rambaut A, Holmes EC, 1999. Widespread intra-serotype recombination in natural populations of dengue virus. Proc Natl Acad Sci USA 96: 7352-7357.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7352-7357
    • Worobey, M.1    Rambaut, A.2    Holmes, E.C.3


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