Modeling and verification of fluid-responsive polymer pumps for microfluidic systems

Chemical Engineering Science

Volumn 59, Issue 24, 2004, Pages 5967-5974

  Good, Brian T ^a   Bowman, Christopher N ^a   Davis, Robert H ^a  

^a University of Colorado   (United States)

Author keywords

Fluid mechanics; Gels; Hydrogels; Modeling; Particles; Polymers

Indexed keywords

COMPUTER SIMULATION; ELEMENTARY PARTICLES; POLYMERS; PUMPS; VOLUME MEASUREMENT;

MICROFLUIDIC SYSTEMS; POLYMER PUMPS; PRESSURE-DRIVEN FLOW;

FLUID DYNAMICS;

FLOW MODELING; FLUID MECHANICS; HYDROGEL;

EID: 10044297087     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2004.07.041     Document Type: Article

References (29)

1. Baldi, A., Gu, Y.D., Loftness, P.E., Siegel, R.A., Ziaie, B., 2003. A hydrogel-actuated environmentally sensitive microvalve for active flow control. Journal of Microelectromechanical Systems 12, 613-621.
2. Beebe, D.J., Moore, J.S., Bauer, J.M., Yu, Q., Liu, R.H., Devadoss, C., Jo, B.H., 2000. Functional hydrogel structures for autonomous flow control inside microfluidic channels. Nature 404, 588-590.
3. Benard, W.L., Kahn, H., Heuer, A.H., Huff, M.A., 1998. Thin-film shape-memory alloy actuated micropumps. Journal of Microelectromechanical Systems 7, 245-251.
4. Bourouina, T., Bosseboeuf, A., Grandchamp, J.P., 1997. Design and simulation of an electrostatic micropump for drug-delivery applications. Journal of Micromechanics and Microengineering.
5. Buchholz, F.L., Graham, A.T. (Ed.), 1998. Modem Superabsorbent Polymer Technology. Wiley, New York, pp. 154-221.
6. Buchholz, F.L., Peppas, N.A. (Ed.), 1994. Superabsorbent Polymers. American Chemical Society, Washington DC, pp. 107-111.
7. Effenhauser, C.S., Harttig, H., Kramer, P., 2002. An evaporation-based disposable micropump concept for continuous monitoring applications. Biomedical Microdevices 4, 27-32.
8. Francais, O., Dufour, I., Sarraute, E., 1997. Analytical static modeling and optimization of electrostatic micropumps. Journal of Micromechanics and Microengineering 7, 183-185.
9. Granik, V.T., Smith, B.R., Lee, S.C., Ferrari, M., 2002. Osmotic pressures for binary solutions of non-electrolytes. Biomedical Microdevices 4, 309-321.
10. Gravesen, P., Braneberg, J., Jensen, O.S., 1993. Microfluidics a review. Journal of Micromechanics and Microengineering 4, 168-182.
11. Guenat, O.T., Ghiglione, D., Morf, W.E., de Roojj, N.F., 2001. Partial electroosmotic pumping in complex capillary systems Part 2: Fabrication and application of a micro total analysis system (mTAS) suited for continuous volumetric nanotitrations. Sensors and Actuators B 72, 273-282.
12. Hartop, W.L., 1975. Expandable Drug Delivery Device. USA, Ortho Pharmaceutical Corp.
13. Hatch, A., Kamholz, A.E., Holman, G., Yager, P., Böhringer, K.F., 2001. A ferrofluidic magnetic micropump. Journal of Microelectromechanical Systems 10, 215-221.
14. Kabra, B., Gehrke, S.H., 1989. Hydrogels for driving an osmotic pump. Abstracts of Papers of the American Chemical Society 197, 259-POLY.
15. Lemoff, A.V., Lee, A.P., 2000. An AC magnetohydrodynamic micropump. Sensors and Actuators B 63, 178-185.
16. Li, P.C.H., Harrison, D.J., 1997. Transport, manipulation and reaction of biological cells on-chip using electrokinetic effects. Analytical Chemistry 69, 1564-1568.
17. Li, Y., Tanaka, T., 1990. Kinetics of swelling and shrinking of gels. Journal of Chemical Physics 92, 1365-1371.
18. Liu, R.H., Yu, Q., Beebe, D.J., 2002. Fabrication and characterization of hydrogel-based microvalves. Journal of Microelectromechanical Systems 11, 45-53.
19. Manz, A., Effenhauser, C.S., Burggraf, N., Harrison, D.J., Seiler, K., Fluri, K., 1994. Electroosmotic pumping and electrophoretic separations for miniaturized chemical analysis systems. Journal of Micromechanics and Microengineering 4, 257-265.
20. Michaels, A.S. 1980. Device using hydrophilic polymer for delivering drug to biological environment. USA, Alza Corp.
21. Persson, B.N.J., 2000. Sliding Friction: Physical Principles and Applications. Springer, New York, pp. 101-109.
22. Rubinstein, M., Colby, R.H., Dobrynin, A.V., Joanny, J.F., 1996. Elastic modulus and equilibrium swelling of polyelectrolyte gels. Macromolecules 29, 398-406.
23. Shoji, S., Esashi, M., 1994. Microflow devices and systems. Journal of Micromechanics and Microengineering 4, 157-171.
24. Soppimath, K.S., Aminabhavi, T.M., Dave, A.M., Kumbar, S.G., Rudzinski, W.E., 2002. Stimulus-responsive "smart" hydrogels as novel drug delivery systems. Drug Development and Industrial Pharmacy 28, 957-974.
25. Su, Y.C., Lin, L.W., Pisano, A.P., 2002. A water-powered osmotic microactuator. Journal of Microelectromechanical Systems 11, 736-742.
26. Theeuwes, F., 1975. Elementary osmotic pump. Journal of Pharmaceutical Sciences 64, 1987-1991.
27. Theeuwes, F., Yum, S.I., 1976. Principles of design and operation of generic osmotic pumps for delivery of semisolid or liquid drug formulations. Annals of Biomedical Engineering 4, 343-353.
28. Whitesides, G.M., Stroock, A.D., 2001. Flexible methods for microfluidics. Physics Today 54, 42-48.
29. Zeng, S., Chen, C., Mikkelsen, J.C., Santiago, J.G., 2001. Fabrication and characterization of electroosmotic micropumps. Sensors and Actuators B 79, 107-114.