Salmonella enterica Serovar Typhimurium RamA, Intracellular Oxidative Stress Response, and Bacterial Virulence

Infection and Immunity

Volumn 72, Issue 2, 2004, Pages 996-1003

  Van Der Straaten, Tahar ^a   Zulianello, Laurence ^a   Van Diepen, Angela ^a   Granger, Donald L ^b   Janssen, Riny ^a   Van Dissel, Jaap T ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CHLORAMPHENICOL; DNA; HYDROGEN PEROXIDE; KANAMYCIN; LINSIDOMINE; MANGANESE SUPEROXIDE DISMUTASE; MENADIONE; NALIDIXIC ACID; NORFLOXACIN; PARAQUAT;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BACTERIAL GENE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; BACTERIUM MUTANT; COLONY FORMING UNIT; FEMALE; GENE MAPPING; GENE OVEREXPRESSION; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAMA GENE; SALMONELLA; SALMONELLA ENTERICA; SALMONELLA TYPHIMURIUM; SALMONELLOSIS;

AMINO ACID SEQUENCE; ANIMALS; ARAC TRANSCRIPTION FACTOR; BACTERIAL PROTEINS; DNA-BINDING PROTEINS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MACROPHAGES; MICE; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; OXIDATIVE STRESS; REGULON; REPRESSOR PROTEINS; SALMONELLA TYPHIMURIUM; SUPEROXIDE DISMUTASE; SUPEROXIDES; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; VIRULENCE;

EID: 0842347930     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.2.996-1003.2004     Document Type: Article

References (33)

1. Amabile-Cuevas, C. F., and B. Demple. 1991. Molecular characterization of the soxRS genes of Escherichia coli: two genes control a superoxide stress regulon. Nucleic Acids Res. 19:4479-4484.
2. Bauer, A. W., W. M. Kirby, J. C. Sherris, and M. Turck. 1966. Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol. 45:493-496.
3. Benson, N. R., and B. S. Goldman. 1992. Rapid mapping in Salmonella typhimurium with Mud-P22 prophages. J. Bacteriol. 174:1673-1681.
4. Cohen, S. P., H. Hachler, and S. B. Levy. 1993. Genetic and functional analysis of the multiple antibiotic resistance (mar) locus in Escherichia coli. J. Bacteriol. 175:1484-1492.
5. Cohen, S. P., L. M. McMurry, and S. B. Levy. 1988. marA locus causes decreased expression of OmpF porin in multiple-antibiotic-resistant (Mar) mutants of Escherichia coli. J. Bacteriol. 170:5416-5422.
6. Fang, F. C., M. A. DeGroote, J. W. Foster, A. J. Baumler, U. Ochsner, T. Testerman, S. Bearson, J. C. Giard, Y. Xu, G. Campbell, and T. Laessig. 1999. Virulent Salmonella typhimurium has two periplasmic Cu, Zn-super-oxide dismutases. Proc. Natl. Acad. Sci. 96:7502-7507.
7. Fang, F. C., A. Vazquez-Torres, and Y. Xu. 1997. The transcriptional regulator SoxS is required for resistance of Salmonella typhimurium to paraquat but not for virulence in mice. Infect. Immun. 65:5371-5375.
8. Farr, S. B., and T. Kogoma. 1991. Oxidative stress responses in Escherichia coli and Salmonella typhimurium. Microbiol. Rev. 55:561-585.
9. Gallegos, M. T., C. Michan, and J. L. Ramos. 1993. The XylS/AraC family of regulators. Nucleic Acids Res. 21:807-810.
10. Gallois, A., J. R. Klein, L. A. Allen, B. D. Jones, and W. M. Nauseef. 2001. Salmonella pathogenicity island 2-encoded type iii secretion system mediates exclusion of NADPH oxidase assembly from the phagosomal membrane. J. Immunol. 166:5741-5748.
11. Gaudu, P., N. Moon, and B. Weiss. 1997. Regulation of the soxRS oxidative stress regulon. Reversible oxidation of the Fe-S centers of SoxR in vivo. J. Biol. Chem. 272:5082-5086.
12. George, A. M., R. M. Hall, and H. W. Stokes. 1995. Multidrug resistance in Klebsiella pneumoniae: a novel gene, ramA, confers a multidrug resistance phenotype in Escherichia coli. Microbiology 141:1909-1920.
13. Groisman, E. A., and M. J. Casadaban. 1986. Mini-Mu bacteriophage with plasmid replicons for in vivo cloning and lac gene fusing. J. Bacteriol. 168:357-364.
14. Lei, S. P., H. C. Lin, L. Heffernan, and G. Wilcox. 1985. araB Gene and nucleotide sequence of the araC gene of Erwinia carotovora. J. Bacteriol. 164:717-722.
15. Ma, D., M. Alberti, C. Lynch, H. Nikaido, and J. E. Hearst. 1996. The local repressor AcrR plays a modulating role in the regulation of acrAB genes of Escherichia coli by global stress signals. Mol. Microbiol. 19:101-112.
16. Nunoshiba, T., T. DeRojas-Walker, J. S. Wishnok, S. R. Tannenbaum, and B. Demple. 1993. Activation by nitric oxide of an oxidative-stress response that defends Escherichia coli against activated macrophages. Proc. Natl. Acad. Sci. 90:9993-9997.
17. Piddock, L. J., D. G. White, K. Gensberg, L. Pumbwe, and D. J. Griggs. 2000. Evidence for an efflux pump mediating multiple antibiotic resistance in Salmonella enterica serovar Typhimurium. Antimicrob. Agents Chemother. 44:3118-3121.
18. Pomposiello, P. J., and B. Demple. 2000. Identification of SoxS-regulated genes in Salmonella enterica serovar Typhimurium. J. Bacteriol. 182:23-29.
19. Rhee, S., R. G. Martin, J. L. Rosner, and D. R. Davies. 1998. A novel DNA-binding motif in MarA: the first structure for an AraC family transcriptional activator. Proc. Natl. Acad. Sci. 95:10413-10418.
20. Rosner, J. L., and G. Storz. 1997. Regulation of bacterial responses to oxidative stress. Curr. Top. Cell. Regul. 35:163-177.
21. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
22. Stoner, C. M., and R. Schleif. 1982. Is the amino acid but not the nucleotide sequence of the Escherichia coli araC gene conserved? J. Mol. Biol. 154:649-652.
23. Tsolis, R. M., A. J. Baumler, and F. Heffron. 1995. Role of Salmonella typhimurium Mn-superoxide dismutase (SodA) in protection against early killing by J774 macrophages. Infect. Immun. 63:1739-1744.
24. van der Straaten, T., A. van Diepen, K. Kwappenberg, S. van Voorden, K. Franken, R. Janssen, J. G. Kusters, D. L. Granger, and J. T. van Dissel. 2001. Novel Salmonella enterica serovar Typhimurium protein that is indispensable for virulence and intracellular replication. Infect. Immun. 69:7413-7418.
25. phox-/- mice. Infect. Immun. 70:2614-2621.
26. van Dissel, J. T., P. C. Leijh, and R. Van Furth. 1985. Differences in initial rate of intracellular killing of Salmonella typhimurium by resident peritoneal macrophages from various mouse strains. J. Immunol. 134:3404-3410.
27. van Dissel, J. T., J. J. Stikkelbroeck, M. T. van den Barselaar, W. Sluiter, P. C. Leijh, and R. Van Furth. 1987. Divergent changes in antimicrobial activity after immunologic activation of mouse peritoneal macrophages. J. Immunol. 139:1665-1672.
28. Vazquez-Torres, A., Y. Xu, J. Jones-Carson, D. W. Holden, S. M. Lucia, M. C. Dinauer, P. Mastroeni, and F. C. Fang. 2000. Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase. Science 287:1655-1658.
29. Wang, R. F., and S. R. Kushner. 1991. Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli. Gene 100:195-199.
30. Wu, J., and B. Weiss. 1992. Two-stage induction of the soxRS (superoxide response) regulon of Escherichia coli. J. Bacteriol. 174:3915-3920.
31. Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33:103-119.
32. Yassien, M. A., H. E. Ewis, C. D. Lu, and A. T. Abdelal. 2002. Molecular cloning and characterization of the Salmonella enterica serovar Paratyphi B rma gene, which confers multiple drug resistance in Escherichia coli. Antimicrob. Agents Chemother. 46:360-366.
33. Youderian, P., P. Sugiono, K. L. Brewer, N. P. Higgins, and T. Elliott. 1988. Packaging specific segments of the Salmonella chromosome with locked-in Mud-P22 prophages. Genetics 118:581-592.