Altered cyclooxygenase-2 expression and nitric oxide metabolism following major elective surgery

Journal of Surgical Research

Volumn 116, Issue 2, 2004, Pages 211-218

  Maddali, Sirish ^a   Stapleton, Philip P ^a,b   Freeman, Tracy A ^a   Yan, Zhaoping ^a   Duff, Michael ^a   Smyth, Gordon P ^a   Daly, John M ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

COX 2; Nitric oxide (NO.); Peripheral blood mononuclear cells (PBMC); PGE2; Surgery

Indexed keywords

CYCLOOXYGENASE 2; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA; NITRIC OXIDE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANALYSIS OF VARIANCE; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; ELECTIVE SURGERY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL ANALYSIS; STUDENT T TEST;

EID: 0842329525     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-4804(03)00344-5     Document Type: Article

References (39)

1. Holzheimer R.G., Gross J., Schein M. Pro- and anti-inflammatory cytokine-response in abdominal aortic aneurysm repair A clinical model of ischemia-reperfusion . Shock. 11:1999;305.
2. Faist E., Kupper T.S., Baker C.C., Chaudry I.H., Dwyer J., Baue A.E. Depression of cellular immunity after major injury. Its association with posttraumatic complications and its reversal with immunomodulation. Arch. Surg. 121:1986;1000.
3. Faist E., Ertel W., Cohnert T., Huber P., Inthorn D., Heberer G. Immunoprotective effects of cyclooxygenase inhibition in patients with major surgical trauma. J. Trauma. 30:1990;8.
4. Lahat N., Shtiller R., Zlotnick A.Y., Merin G. Early IL-2/sIL-2R surge following surgery leads to temporary immune refractoriness. Clin. Exp. Immunol. 92:1993;482.
5. Lin E., Calvano S.E., Lowry S.F. Inflammatory cytokines and cell response in surgery. Surgery. 127:2000;117.
6. Schinkel C., Licht K., Zedler S., Schinkel S., Fraunberger P., Fuchs D., Neugebauer E., Kreuzer E., Faist E. Interferon-γ modifies cytokine release in vitro by monocytes from surgical patients. J. Trauma. 50:2001;321.
7. Strong V.E., Winter J., Yan Z., Smyth G.P., Mestre J.R., Maddali S., Schaefer P.A., Yurt R.W., Stapleton P.P., Daly J.M. Prostaglandin E2 receptors EP2 and EP4 are down-regulated in human mononuclear cells after injury. Surgery. 130:2001;249.
8. 2)-dependent suppression of interleukin α (IL-2) production in patients with major trauma. J. Trauma. 27:1987;837.
9. Schwacha M.G., Samy T.S., Catania R.A., Chaudry I.H. Thermal injury alters macrophage responses to prostaglandin E2 Contribution to the enhancement of inducible nitric oxide synthase activity . J. Leukocyte Biol. 64:1998;740.
10. Braun W., Ishizuka M. Antibody formation Reduced responses after administration of excessive amounts of nonspecific stimulators . Proc. Natl. Acad. Sci. USA. 68:1971;1114.
11. Waymack J.P., Yurt R.W. Effect of prostaglandin E on immune function in multiple animal models. Arch. Surg. 123:1988;1429.
12. Park K.G., Hayes P.D., Garlick P.J., Sewell H., Eremin O. Stimulation of lymphocyte natural cytotoxicity by L-arginine. Lancet. 337:1991;645.
13. Beckerman K.P., Rogers H.W., Corbett J.A., Schreiber R.D., McDaniel M.L., Unanue E.R. Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes. J. Immunol. 150:1993;888.
14. Kubes P., Kanwar S., Niu X.F., Gaboury J.P. Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells. FASEB J. 7:1993;1293.
15. McInnes I.B., Leung B.P., Field M., Wei X.Q., Huang F.P., Sturrock R.D., Kinninmonth A., Weidner J., Mumford R., Liew F.Y. Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. J. Exp. Med. 184:1996;1519.
16. Brinkmann A., Seeling W., Wolf C.F., Kneitinger E., Vogeser F., Rockemann M., Bruckner U., Radermacher P., Buchler M., Georgieff M. The impact of prostanoids on pulmonary gas exchange during abdominal surgery with mesenteric traction. Anesth. Analg. 85:1997;274.
17. Gebhard F.T., Becker H.P., Gerngross H., Bruckner U.B. Reduced inflammatory response in minimal invasive surgery of pneumothorax. Arch. Surg. 131:1996;1079.
18. Shimada M., Matsumata T., Taketomi A., Shirabe K., Yamamoto K., Sugimachi K. The role of prostaglandins in hepatic resection. Prostaglandins Leukot. Essent. Fatty Acids. 50:1994;65.
19. Schulze S., Sommer P., Bigler D., Honnens M., Shenkin A., Cruickshank A.M., Bukhave K., Kehlet H. Effect of combined prednisolone, epidural analgesia, and indomethacin on the systemic response after colonic surgery. Arch. Surg. 127:1992;325.
20. Baxevanis C.N., Papilas K., Dedoussis G.V., Pavlis T., Papamichail M. Abnormal cytokine serum levels correlate with impaired cellular immune responses after surgery. Clin. Immunol. Immunopathol. 71:1994;82.
21. Brinkmann A., Seeling W., Wolf C.F., Kneitinger E., Vogt N., Steinbach G., Orend K.H., Radermacher P., Georgieff M. Ibuprofen does not impair renal function in patients undergoing infrarenal aortic surgery with epidural anaesthesia. Intensive Care Med. 24:1998;322.
22. Kort W.J., Bijma A.M., van Dam J.J., van der Ham A.C., Hekking J.M., van der Ingh H.F., Meijer W.S., van Wilgenburg M.G., Zijlstra F.J. Eicosanoids in breast cancer patients before and after mastectomy. Prostaglandins Leukot. Essent. Fatty Acids. 45:1992;319.
23. Satoi S., Kamiyama Y., Kitade H., Kwon A.H., Yoshida H., Nakamura N., Takai S., Uetsuji S., Okuda K., Hara K., Takahashi H. Prolonged decreases in plasma nitrate levels at early postoperative phase after hepato-pancreato- biliary surgery. J. Lab. Clin. Med. 131:1998;236.
24. Arias - Diaz J., Rodriguez J.M., Vara E., Garcia C., Torres-Melero J., Garcia - Carreras C., Balibrea J.L. NO2/NO3 and cytokine plasma profiles under different postoperative parenteral nutrition regimens. Nutrition. 12:1996;89.
25. Ioannidis I., Hellinger A., DehmLow C., Rauen U., Erhard J., Eigler F.W., De Groot H. Evidence for increased nitric oxide production after liver transplantation in humans. Transplantation. 59:1995;1293.
26. Ruvolo G., Speziale G., Greco E., Tritapepe L., Mollace V., Nistico G., Marino B. Nitric oxide release during hypothermic versus normothermic cardiopulmonary bypass. Eur. J. Cardiothorac. Surg. 9:1995;651.
27. Brett S.J., Quinlan G.J., Mitchell J., Pepper J.R., Evans T.W. Production of nitric oxide during surgery involving cardiopulmonary bypass. Crit. Care Med. 26:1998;272.
28. Moojen T.M., Van Gulik T.M., Hoek F.J., Gouma D.J., Tytgat G.N., Boeckxstaens G.E. Possible role of nitric oxide in postoperative ileus A comparative study . Neurogastroenterol. Motil. 11:1999;403.
29. Fujioka S., Mizumoto K., Okada K. A decreased serum concentration of nitrite/nitrate correlates with an increased plasma concentration of lactate during and after major surgery. Surg. Today. 30:2000;871.
30. Fedyk E.R., Ripper J.M., Brown D.M., Phipps R.P. A molecular analysis of PGE receptor (EP) expression on normal and transformed b lymphocytes Coexpression of EP1, EP2, EP3β and EP4 . Mol. Immunol. 33:1996;33.
31. Boie Y., Stocco R., Sawyer N., Slipetz D.M., Ungrin M.D., Neuschafer-Rube F., Puschel G., Metters K.M., Abramovitz M. Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. Eur. J. Pharmacol. 340:1997;227.
32. Misko T.P., Schilling R.J., Salvemini D., Moore W.M., Currie M.G. A fluorometric assay for the measurement of nitrite in biological samples. Anal. Biochem. 214:1993;11.
33. Johnson M.L., Billiar T.R. Roles of nitric oxide in surgical infection and sepsis. World J. Surg. 22:1982;187.
34. Ochoa J.B., Udekwu A.O., Billiar T.R., Curran R.D., Cerra F.B., Simmons R.L., Peitzman A.B. Nitrogen oxide levels in patients after trauma and during sepsis. Ann. Surg. 214:1991;621.
35. Perkins D.J., Kniss D.A. Blockade of nitric oxide formation down-regulates cyclooxygenase-2 and decreases PGE2 biosynthesis in macrophages. J. Leukocyte Biol. 65:1999;792.
36. Pang L., Hoult J.R. Repression of inducible nitric oxide synthase and cyclooxygenase-2 by prostaglandin E2 and other cyclic amp stimulants in J774 macrophages. Biochem. Pharmacol. 53:1997;493.
37. Milano S., Arcoleo F., Dieli M., D'Agostino R., D'Agostino P., De Nucci G., Cillari E. Prostaglandin E2 regulates inducible nitric oxide synthase in the murine macrophage cell line J774. Prostaglandins. 49:1995;105.
38. Leung K.L., Lai P.B., Ho R.L., Meng W.C., Yiu R.Y., Lee J.F., Lau W.Y. Systemic cytokine response after laparoscopic-assisted resection of rectosigmoid carcinoma A prospective randomized trial . Ann. Surg. 231:2000;506.
39. Yamauchi H., Kobayashi E., Yoshida T., Kiyozaki H., Hozumi Y., Kohiyama R., Suminaga Y., Sakurabayashi I., Fujimura A., Miyata M. Changes in immune-endocrine response after surgery. Cytokine. 10:1998;549.