Cyclosporine-A induced nephrotoxicity is associated with decreased renal bone morphogenetic protein-7 expression in rats

Transplantation Proceedings

Volumn 36, Issue 1, 2004, Pages 131-133

  Tuglular S ^a,b   Yavuz, D Gogas ^a   Cakalagaoglu F ^a   Citak L ^a   Arikan, H ^a   Kocak H ^a   Ozener C ^a   Akoglu E ^a  

^a MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b NONE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

AQUITEL; CREATININE; CYCLOSPORIN A; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DRINKING WATER; OSTEOGENIC PROTEIN 1; QUINAPRIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DISEASE; ATROPHY; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; DISEASE MODEL; DRUG EFFECT; ENZYME INHIBITION; HISTOPATHOLOGY; HYALINE DEGENERATION; IMMUNOHISTOCHEMISTRY; INTERSTITIAL NEPHRITIS; KIDNEY FIBROSIS; KIDNEY PARENCHYMA; KIDNEY TUBULE DISORDER; LONG TERM EXPOSURE; MALE; MICROSCOPY; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT;

EID: 0842324828     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2003.11.018     Document Type: Conference Paper

References (6)

1. Lund R.J., Davies M.R., Hruska K. Bone morphogenetic protein-7 an anti-fibrotic morphogenetic protein with therapeutic-importance in renal disease . Curr Opin Nephrol Hypertens. 11:2002;31.
2. Klahr S., Morrissey J., Hruska K., et al. New approaches to delay the progression of chronic renal failure. Kidney Int. 61:(suppl 80):2002;S23.
3. Hruska K.A. Treatment of chronic tubulointerstitial disease a new concept . Kidney Int. 61:2002;1911-1922.
4. Morissey J., Hruska K., Guo G., et al. Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function. J Am Soc Nephrol. 13:(suppl):2002;S14.
5. Young B.A., Burdmann E.A., Johnson R.J., et al. Cyclosporine A induced arteriolopathy in a rat model of chronic cyclosporine nephropathy. Kidney Int. 48:1995;431.
6. Young B.A., Burdmann E.A., Johnson R.J., et al. Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity. Kidney Int. 48:1995;439.