Surprisingly Stable Helical Conformations in α/β-Peptides by Incorporation of cis-β-Aminocyclopropane Carboxylic Acids

Angewandte Chemie - International Edition

Volumn 43, Issue 4, 2004, Pages 511-514

  De Pol, Silvia ^a   Zorn, Chiara ^a   Klein, Christian D ^c   Zerbe, Oliver ^b   Reiser, Oliver ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

peptides; amino acids; Foldamers; Helical structures; NMR spectroscopy

Indexed keywords

CARBOXYLIC ACIDS; CONFORMATIONS; STRUCTURE (COMPOSITION);

FOLDAMER; HELICAL STRUCTURE;

AMINO ACIDS;

ALANINE; CYCLOPROPANECARBOXYLIC ACID DERIVATIVE;

ALPHA HELIX; ARTICLE; BETA CHAIN; CIS ISOMER; MOLECULAR STABILITY; NUCLEAR OVERHAUSER EFFECT; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY;

ALANINE; AMINO ACIDS; AMINO ACIDS, CYCLIC; COMPUTER SIMULATION; CYCLOPROPANES; ELECTROSTATICS; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; METHANOL; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SOLVENTS; STEREOISOMERISM; TEMPERATURE;

EID: 0842307523     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200352267     Document Type: Article

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33. See also: A. Hayen, M. A. Schmitt, F. N. Ngassa, K. A. Thomasson, S. H. Gellman, Angew. Chem. 2004, 116, 511; Angew. Chem. Int. Ed. 2004, 43, 505.