Is the Volume-Regulated Anion Channel VRAC a "Water-Permeable" Channel?

Neurochemical Research

Volumn 29, Issue 1, 2004, Pages 3-8

  Nilius, Bernd ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Cl channels; Volume regulation; Volume regulated anion channels; Water permeability

Indexed keywords

CHLORIDE CHANNEL; WATER;

ANIMAL CELL; ARTICLE; CATTLE; CELL MEMBRANE PERMEABILITY; CHANNEL GATING; DIFFUSION; ENDOTHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; TRANSPORT KINETICS; WATER PERMEABILITY; WATER TRANSPORT;

ANIMALS; ANIONS; CATTLE; CELL LINE; ION CHANNELS; PERMEABILITY; PULMONARY ARTERY; WATER;

ANIMALIA; BOS TAURUS;

EID: 0842301325     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000010430.23137.be     Document Type: Article

References (23)

1. Pasantes-Morales, H. 1996. Volume regulation in brain cells: Cellular and molecular mechanisms. Metab. Brain Dis. 11: 187-204.
2. Nilius, B. and Droogmans, G. 2003. Amazing chloride channels: An overview. Acta Physiol. Scand. 177:119-147.
3. - channels. Gen. Pharmacol. 27:1131-1140.
4. Nilius, B., Voets, T., Eggermont, J., and Droogmans, G. 1999. VRAC: A multifunctional volume regulated anion channel in vascular endothelium. Pages 47-63 in Kozlowski, R. (ed.), Chloride channels, Oxford, UK: Isis Medical Media Limited.
5. Nilius, B., Eggermont, J., Voets, T., Buyse, G., Manolopoulos, V., and Droogmans, G. 1997. Properties of volume-regulated anion channels in mammalian cells. Prog. Biophys. Mol. Biol. 68:69-119.
6. - channel: Fresh start to the molecular identity and volume sensor. Am. J. Physiol. 273:C755-C789.
7. Strange, K., Emma, F., and Jackson P. S. 1996. Cellular and molecular physiology of volume-sensitive anion channels. Am. J. Physiol. 270:C711-C730.
8. Alexander, S. P. H. and Peters, J. A. 1999. Receptor and ion channel nomenclature supplement. Trends Pharmacol. Sci. 20 (Suppl):92.
9. Okada, Y. and Maeno, E. 2001. Apoptosis, cell volume regulation and volume-regulatory chloride channels. Comp. Biochem. Physiol. Mol. Integr. Physiol. 130:377-383.
10. Okada, Y., Maeno, E., Shimizu, T., Dezaki, K., Wang, J., and Morishima, S. 2001. Receptor-mediated control of regulatory volume decrease (RVD) and apoptotic volume decrease (AVD). J. Physiol. (Lond.) 532:3-16.
11. Eggermont, J., Trouet, D., Carton, I. and Nilius, B. 2001. Cellular function and control of volume-regulated anion channels. Cell Biochem. Biophys. 35:263-274.
12. Hisadome, K., Koyama, T., Kimura, C., Droogmans, G., Ito, Y., and Oike, M. 2002. Volume-regulated anion channels serve as an auto/paracrine nucleotide release pathway in aortic endothelial cells. J. Gen. Physiol. 119:511-520.
13. Droogmans, G., Prenen, J., Eggermont, J., Voets, T., and Nilius, B. 1998. Voltage-dependent block of endothelial volume-regulated anion channels by calix[4]arenes. Am. J. Physiol. 275: C646-C652.
14. Halm, D. R. 1998. Identifying swelling-activated channels from ion selectivity patterns. J. Gen. Physiol. 112:369-371.
15. Voets, T., Droogmans, G., Raskin, G., Eggermont, J., and Nilius, B. 1999. Reduced intracellular ionic strength as the initial trigger for activation of endothelial volume-regulated anion channels. Proc. Natl. Acad. Sci. USA 96:5298-5303.
16. Nilius, B., Prenen, J., Voets, T., Eggermont, J., and Droogmans, G. 1998. Reduction of intracellular ionic strength activates the volume-regulated chloride current in cultured bovine pulmonary endothelial cells. J. Physiol. (Lond.) 506:353-361.
17. Nilius, B., Voets, T., Prenen, J., Barth, H., Aktories, K., Kaibuchi, K., Droogmans, G., and Eggermont, J. 1999. Role of RhoA and Rho kinase in the activation of volume-regulated anion channels in bovine endothelial cells. J. Physiol. (Lond.) 516:67-74.
18. Van Driessche, W., De Smet, P., and Raskin, G. 1993. An automatic monitoring system for epithelial cell height. Pflügers Arch. Eur. J. Physiol. 425:164-171.
19. Sabirov, R. Z., Morishima, S., and Okada, Y. 1998. Probing the water permeability of ROMK1 and amphotericin B channels using Xenopus oocytes. Biochim. Biophys. Acta 1368:19-26.
20. Yasui, M., Hazama, A., Kwon, T. H., Nielsen, S., Guggino, W. B., and Agre, P. 1999. Rapid gating and anion permeability of an intracellular aquaporin. Nature 402:184-187.
21. Saparov, S. M., Kozono, D., Rothe, U., Agre, P., and Pohl, P. 2001. Water and ion permeation of aquaporin-1 in planar lipid bilayers: Major differences in structural determinants and stoichiometry. J. Biol. Chem. 276:31515-31520.
22. Schnitzer, J. E. and Oh, P. 1996. Aquaporin-1 in plasma membrane and caveolae provides mercury-sensitive water channels across lung endothelium. Am. J. Physiol. 270:H416-H422.
23. Heinke, S., Raskin, G., De Smet, P., Droogmans, G., Van Driessche, W., and Nilius, B. 1997. Simultaneous measurements of membrane capacitance and whole cell currents during cell swelling in macrovascular endothelium. Cell. Physiol. Biochem. 7:19-24.