α-Nitro Ketone As An Electrophile and Nucleophile: Synthesis of 3-Substituted 2-Nitromethylenetetrahydrothiophene and -Tetrahydrofuran As Drosophila Nicotinic Receptor Probes

Journal of Organic Chemistry

Volumn 69, Issue 3, 2004, Pages 876-881

  Zhang, Nanjing ^a   Tomizawa, Motohiro ^a   Casida, John E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOMERS; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

ELECTROPHILES; NUCLEOPHILES;

KETONES;

2 NITROMETHYLENEPYRROLIDINE; 3 (6 CHLOROPYRIDIN 3 YL)METHYL 2 NITROMETHYLENETETRAHYDROFURAN; 3 (6 CHLOROPYRIDIN 3 YL)METHYL 2 NITROMETHYLENETETRAHYDROTHIOPHENE; CARBONYL DERIVATIVE; IMIDACLOPRID; INSECTICIDE; KETONE; NICOTINIC RECEPTOR; NITRO DERIVATIVE; PYRIDINE DERIVATIVE; PYRROLIDINE DERIVATIVE; TETRAHYDROFURAN DERIVATIVE; TETRAHYDROTHIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DROSOPHILA; DRUG RECEPTOR BINDING; NONHUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; DROSOPHILA; FURANS; ISOMERISM; KETONES; MOLECULAR PROBES; NITRO COMPOUNDS; PROTEIN BINDING; PYRROLIDINES; RECEPTORS, NICOTINIC; THIOPHENES;

EID: 0842285774     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo035457g     Document Type: Article

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