메뉴 건너뛰기




Volumn 74, Issue 1, 2004, Pages 55-59

Effects of 24 Months of Growth Hormone (GH) Treatment on Serum Carboxylated and Undercarboxylated Osteocalcin Levels in GH-Deficient Adults

Author keywords

Bone mass; Growth hormone replacement; Undercarboxylated osteocalcin

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM PHOSPHATE; GROWTH HORMONE; OSTEOCALCIN; PARATHYROID HORMONE;

EID: 0842283931     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-002-2149-4     Document Type: Article
Times cited : (18)

References (39)
  • 2
    • 0027203108 scopus 로고
    • Growth hormone and bone
    • Wuster C (1993) Growth hormone and bone. Acta Endocrinol 128:S14-S18
    • (1993) Acta Endocrinol , vol.128
    • Wuster, C.1
  • 3
    • 0027363782 scopus 로고
    • Reduced bone mineral content in adult patients with growth hormone deficiency
    • Rosen T, Hansson T, Granhed H, Szucs J, Bengtsson B-A (1993) Reduced bone mineral content in adult patients with growth hormone deficiency. Acta Endocrinol 129:201-206
    • (1993) Acta Endocrinol , vol.129 , pp. 201-206
    • Rosen, T.1    Hansson, T.2    Granhed, H.3    Szucs, J.4    Bengtsson, B.-A.5
  • 7
    • 0034519223 scopus 로고    scopus 로고
    • Fracture rates in patients with growth hormone deficiency
    • Wuster C (2000) Fracture rates in patients with growth hormone deficiency. Horm Res 54:31-35
    • (2000) Horm Res , vol.54 , pp. 31-35
    • Wuster, C.1
  • 10
    • 0031808446 scopus 로고    scopus 로고
    • Serum collagen crosslink as marker of bone turn-over during GH replacement therapy in growth hormone-deficient adults
    • Rodriguez-Arnao J, James I, Jabbar A, Trainer PJ, Perrett D, Besser GM, Ross RJ (1998) Serum collagen crosslink as marker of bone turn-over during GH replacement therapy in growth hormone-deficient adults. Clin Endocrinol 48:455-462
    • (1998) Clin Endocrinol , vol.48 , pp. 455-462
    • Rodriguez-Arnao, J.1    James, I.2    Jabbar, A.3    Trainer, P.J.4    Perrett, D.5    Besser, G.M.6    Ross, R.J.7
  • 11
    • 0034011568 scopus 로고    scopus 로고
    • Effects of long-term treatment with GH in the bone mineral density of adults with hypopituitarism and GH deficiency and after discontinuation of GH replacement
    • Gomez JM, Gomez N, Fiter J, Soler J (2000) Effects of long-term treatment with GH in the bone mineral density of adults with hypopituitarism and GH deficiency and after discontinuation of GH replacement. Horm Metab Res 32:66-70
    • (2000) Horm Metab Res , vol.32 , pp. 66-70
    • Gomez, J.M.1    Gomez, N.2    Fiter, J.3    Soler, J.4
  • 13
    • 0026767143 scopus 로고
    • The effect of growth hormone administration in growth hormone-deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as on body composition
    • Binnerts A, Swart GR, Wilson JH, Hoogerbrugge N, Pols HA, Birkenhager JC, Lamberts SW (1992) The effect of growth hormone administration in growth hormone-deficient adults on bone, protein, carbohydrate and lipid homeostasis, as well as on body composition. Clin Endocrinol 37:79-87
    • (1992) Clin Endocrinol , vol.37 , pp. 79-87
    • Binnerts, A.1    Swart, G.R.2    Wilson, J.H.3    Hoogerbrugge, N.4    Pols, H.A.5    Birkenhager, J.C.6    Lamberts, S.W.7
  • 14
    • 0031792733 scopus 로고    scopus 로고
    • Effects of short-term insulin-like growth factor-I (IGF-I) or growth hormone (GH) treatment on bone metabolism and on production of 1,25-dihydroxychole-calciferol in GH-deficient adults
    • Bianda TM, Glatz Y, Bouillon R, Froesch ER, Schmid C (1998) Effects of short-term insulin-like growth factor-I (IGF-I) or growth hormone (GH) treatment on bone metabolism and on production of 1, 25-dihydroxychole-calciferol in GH-deficient adults. J Clin Endocrinol Metab 83:81-87
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 81-87
    • Bianda, T.M.1    Glatz, Y.2    Bouillon, R.3    Froesch, E.R.4    Schmid, C.5
  • 15
    • 0034527637 scopus 로고    scopus 로고
    • Growth hormone replacement therapy improves body composition and increases bone metabolism in elderly patients with pituitary disease
    • Fernholm R, Bramnert M, Hagg E, Hilding A, Baylink DJ, Mohan S, Thoren M (2000) Growth hormone replacement therapy improves body composition and increases bone metabolism in elderly patients with pituitary disease. J Clin Endocrinol Metab 85:4104-4112
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 4104-4112
    • Fernholm, R.1    Bramnert, M.2    Hagg, E.3    Hilding, A.4    Baylink, D.J.5    Mohan, S.6    Thoren, M.7
  • 17
    • 0030483350 scopus 로고    scopus 로고
    • Dose-dependent effects of recombinant human growth hormone on biochemical markers of bone and collagen metabolism in adult growth hormone deficiency
    • Bollerslev J, Moller J, Thomas S, Djoseland O, Christiansen JS (1996) Dose-dependent effects of recombinant human growth hormone on biochemical markers of bone and collagen metabolism in adult growth hormone deficiency. Eur J Endocrinol 135:666-671
    • (1996) Eur J Endocrinol , vol.135 , pp. 666-671
    • Bollerslev, J.1    Moller, J.2    Thomas, S.3    Djoseland, O.4    Christiansen, J.S.5
  • 18
    • 8044255242 scopus 로고    scopus 로고
    • Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment
    • Adult Growth Hormone Deficiency Study Group
    • Attanasio AF, Lamberts SW, Matranga AM, Birkett MA, Bates PC, Valk NK, Hilsted J, Bengtsson B-A, Strasburger CJ (1997) Adult growth hormone (GH)-deficient patients demonstrate heterogeneity between childhood onset and adult onset before and during human GH treatment. Adult Growth Hormone Deficiency Study Group. J Clin Endocrinol Metab 82:82-88
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 82-88
    • Attanasio, A.F.1    Lamberts, S.W.2    Matranga, A.M.3    Birkett, M.A.4    Bates, P.C.5    Valk, N.K.6    Hilsted, J.7    Bengtsson, B.-A.8    Strasburger, C.J.9
  • 20
    • 0031156847 scopus 로고    scopus 로고
    • The effect of growth hormone (GH) on histomorphometric indices of bone structure and bone turnover in GH-deficient men
    • Bravenboer N, Holzmann P, de Boer H, Roos JC, van der Veen EA, Lips P (1997) The effect of growth hormone (GH) on histomorphometric indices of bone structure and bone turnover in GH-deficient men. J Clin Endocrinol Metab 82:1818-1822
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 1818-1822
    • Bravenboer, N.1    Holzmann, P.2    De Boer, H.3    Roos, J.C.4    Van Der Veen, E.A.5    Lips, P.6
  • 23
  • 25
    • 0031931910 scopus 로고    scopus 로고
    • Age-related changes in serum undercarboxylated osteocalcin and its relationships with bone density, bone quality, and hip fracture
    • Liu G, Peacock M (1998) Age-related changes in serum undercarboxylated osteocalcin and its relationships with bone density, bone quality, and hip fracture. Calcif Tissue Int 62:286-289
    • (1998) Calcif Tissue Int , vol.62 , pp. 286-289
    • Liu, G.1    Peacock, M.2
  • 26
    • 0034980829 scopus 로고    scopus 로고
    • Carboxylation of osteocalcin may be related to bone quality: A possible mechanism of bone fracture prevention by vitamin K
    • Sugiyama T, Kawai S (2001) Carboxylation of osteocalcin may be related to bone quality: a possible mechanism of bone fracture prevention by vitamin K. J Bone Miner Res 19:146-149
    • (2001) J Bone Miner Res , vol.19 , pp. 146-149
    • Sugiyama, T.1    Kawai, S.2
  • 27
    • 0027232105 scopus 로고
    • Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women
    • Szulc P, Chapuy MC, Meunier PJ, Delmas PD (1993) Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture in elderly women. J Clin Invest 91: 1769-1774
    • (1993) J Clin Invest , vol.91 , pp. 1769-1774
    • Szulc, P.1    Chapuy, M.C.2    Meunier, P.J.3    Delmas, P.D.4
  • 28
    • 0028147029 scopus 로고
    • Serum undercarboxylated osteocalcin correlates with hip bone mineral density in elderly women
    • Szulc P, Arlot M, Chapuy MC, Duboeuf F, Meunier PJ, Delmas PD (1994) Serum undercarboxylated osteocalcin correlates with hip bone mineral density in elderly women. J Bone Miner Res 9:1591-1595
    • (1994) J Bone Miner Res , vol.9 , pp. 1591-1595
    • Szulc, P.1    Arlot, M.2    Chapuy, M.C.3    Duboeuf, F.4    Meunier, P.J.5    Delmas, P.D.6
  • 29
    • 0029879059 scopus 로고    scopus 로고
    • Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture: A three-year follow-up study
    • Szulc P, Chapuy MC, Meunier PJ, Delmas PD (1996) Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture: a three-year follow-up study. Bone 18:487-488
    • (1996) Bone , vol.18 , pp. 487-488
    • Szulc, P.1    Chapuy, M.C.2    Meunier, P.J.3    Delmas, P.D.4
  • 30
    • 0025149295 scopus 로고
    • Normal carboxylation of circulating osteocalcin (bone Gla-protein) in Paget's disease of bone
    • Merle B, Delmas PD (1990) Normal carboxylation of circulating osteocalcin (bone Gla-protein) in Paget's disease of bone. Bone Miner 11:237-245
    • (1990) Bone Miner , vol.11 , pp. 237-245
    • Merle, B.1    Delmas, P.D.2
  • 31
    • 0031044021 scopus 로고    scopus 로고
    • Undercarboxylated osteocalcin measured with a specific immunoassay predicts hip fracture in elderly women: The EPIDOS Study
    • Vergnaud P, Garnero P, Meunier PJ, Breatr G, Kamihagi K, Delmas PD (1997) Undercarboxylated osteocalcin measured with a specific immunoassay predicts hip fracture in elderly women: the EPIDOS Study. J Clin Endocrinol Metab 82:719-724
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 719-724
    • Vergnaud, P.1    Garnero, P.2    Meunier, P.J.3    Breatr, G.4    Kamihagi, K.5    Delmas, P.D.6
  • 33
    • 0027217259 scopus 로고
    • The epidemiology of fragility fractures: Is there a role for bone quality?
    • Coopper C (1993) The epidemiology of fragility fractures: Is there a role for bone quality? Calcif Tissue Int 53:S23-S26
    • (1993) Calcif Tissue Int , vol.53
    • Coopper, C.1
  • 34
    • 0027313510 scopus 로고
    • Bone quality: A determinant for certain risk factors for bone fragility
    • Schnitzler CM (1993) Bone quality: a determinant for certain risk factors for bone fragility. Calcif Tissue Int 53:S27-S31
    • (1993) Calcif Tissue Int , vol.53
    • Schnitzler, C.M.1
  • 35
    • 0035127621 scopus 로고    scopus 로고
    • Effect of vitamin K and/or D on undercarboxylated and intact osteocalcin in osteoporotic patients with vertebral or hip fractures
    • Takahashi M, Naitou K, Ohishi T, Kushida K, Miura M (2001) Effect of vitamin K and/or D on undercarboxylated and intact osteocalcin in osteoporotic patients with vertebral or hip fractures. Clin Endocrinol 54:219-224
    • (2001) Clin Endocrinol , vol.54 , pp. 219-224
    • Takahashi, M.1    Naitou, K.2    Ohishi, T.3    Kushida, K.4    Miura, M.5
  • 36
    • 0031792815 scopus 로고    scopus 로고
    • Vitamin K status and bone health: An analysis of methods for determination of undercarboxylated osteocalcin
    • Gundberg CM, Nieman SD, Abrams S, Rosen H (1998) Vitamin K status and bone health: an analysis of methods for determination of undercarboxylated osteocalcin. J Clin Endocrinol Metab 83:3258-3266
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3258-3266
    • Gundberg, C.M.1    Nieman, S.D.2    Abrams, S.3    Rosen, H.4
  • 37
    • 0033660336 scopus 로고    scopus 로고
    • Vitamin K supplementation reduces serum concentration of under-γ-carboxylated osteocalcin in healthy young and elderly adults
    • Binkley NC, Krueger DC, Engelke JA, Foley AL, Suttie JW (2000) Vitamin K supplementation reduces serum concentration of under-γ-carboxylated osteocalcin in healthy young and elderly adults. Am J Clin Nutr 72:1523-1528
    • (2000) Am J Clin Nutr , vol.72 , pp. 1523-1528
    • Binkley, N.C.1    Krueger, D.C.2    Engelke, J.A.3    Foley, A.L.4    Suttie, J.W.5
  • 39
    • 0035744490 scopus 로고    scopus 로고
    • Effects of vitamin K on calcium and bone metabolism
    • Zittermann A (2001) Effects of vitamin K on calcium and bone metabolism. Curr Opin Clin Nutr Metab Care 4: 483-487
    • (2001) Curr Opin Clin Nutr Metab Care , vol.4 , pp. 483-487
    • Zittermann, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.