Is blood donation induced low iron status associated with favourable levels of OxLDL, s-ICAM-1, sVCAM-1 and vWF-antigen in healthy men

Atherosclerosis

Volumn 172, Issue 2, 2004, Pages 321-327

  Van Hoydonck, Pascale G A ^a   Schouten, Evert G ^a   Hoppenbrouwers, Karel P M ^a   Temme, Elisabeth H M ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Blood donation; Iron status; Vascular endothelium

Indexed keywords

ANTIGEN; FERRITIN; HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERCELLULAR ADHESION MOLECULE 1; IRON; LOW DENSITY LIPOPROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; AGED; ARTICLE; BLOOD DONOR; BLOOD SAMPLING; CONTROLLED STUDY; DEMOGRAPHY; DIET RESTRICTION; DISEASE ASSOCIATION; HEMATOCRIT; HUMAN; IRON BLOOD LEVEL; IRON DEFICIENCY; LIPID OXIDATION; MALE; NORMAL HUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

EID: 0842281420     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2003.11.006     Document Type: Article

References (25)

1. Tuomainen T.-P., Salonen R., Nyyssönen K., Salonen J.T. Cohort study of relation between donating blood and risk of myocardial infarction in 2682 men in eastern Finland. BMJ. 314:1997;793-794.
2. Salonen J.T., Tuomainen T.-P., Salonen R., Lakka T.A., Nyyssönen K. Donation of blood is associated with reduced risk of myocardial infarction. The Kuopio Ischaemic Heart Disease Risk Factor Study. Am. J. Epidemiol. 148:1998;445-451.
3. Meyers D.G., Strickland D., Maloley P.A., Seburg J.J., Wilson J.E., McManus B.F. Possible association of a reduction in cardiovascular events with blood donation. Heart. 78:1997;188-193.
4. Meyers D.G., Kelly C.J., Menitove J.E. A historical cohort study of the effect of lowering body iron through blood donation on incident cardiac events. Transfusion. 42:2002;1135-1139.
5. Milman N., Kirchhoff M. Influence of blood donation on iron stores assessed by serum ferritin and haemoglobin in a population survey of 1433 Danish males. Eur. J. Haematol. 47:1991;134-139.
6. Finch C.A., Cook J.D., Labbe R.F., Culala M. Effect of blood donation on iron stores as evaluated by serum ferritin. Blood. 50:1977;441-447.
7. Sullivan J.L. The iron paradigm of ischemic heart disease. Am. Heart J. 117:1989;1177-1188.
8. Welch K.D., Davis T.Z., Van Eden M.E., Aust S.D. Deleterious iron-mediated oxidation of biomolecules. Free Radic. Biol. Med. 32:2002;577-583.
9. Ascherio A., Rimm E.B., Giovannucci E., Wilett W.C., Stampfer M.J. Blood donations and risk of coronary heart disease in men. Circulation. 103:2001;52-57.
10. Minotti G., Aust S.D. Redox cycling of iron and lipid peroxidation. Lipids. 27:1992;219-226.
11. Holvoet P. Endothelial dysfunction, oxidation of low-density lipoprotein, and cardiovascular disease. Ther. Apher. 3:1999;287-293.
12. Penn M.S., Chisolm G.M. Oxidised lipoproteins, altered cell function and atherosclerosis. Atherosclerosis. 108:1994;S21-29.
13. McCord J.M. Is iron sufficiency a risk factor in ischemic heart disease. Circulation. 83:1991;1112-1114.
14. Halliwell B,Gutteridge JM., Role of free radicals and catalytic metal ions in human disease: an overview. In: Packer L, Glazer AN, editors. Methods in enzymology, vol 186. San Diego: Academic Press, 1990. p. 1-85.
15. Friedewald W.T., Levy R.I., Fredrikson D.S. Estimation of the concentration of the low-denstity lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18:1972;499-502.
16. Holvoet P., Perez G., Bernar H., Brouwens E., Vanloo B., Rosseneu M., Collen D. Stimulation with a monoclonal antibody (mAb4E4) of scavenger receptor-mediated uptake of chemically modified low density lipoproteins by THP-1 derived macrophages enhances foam cell generation. J. Clin. Invest. 93:1994;89-98.
17. Holvoet P., Donck J., Landeloos M., Brouwers E., Luijtens K., Arnout J. et al. Correlation between oxidised low density lipoproteins and von Willebrand factor in chronic renal failure. Thromb Haemost. 76:1996;663-669.
18. Derstine J.L., Murray-Kolb L.E., Yu-Poth S., Hargrove R.L., Kris-Etherton P.M., Beard J.L. Iron status in association with cardiovascular disease risk in 3 controlled feeding studies. Am. J. Clin. Nutr. 77:2003;56-61.
19. Williams M.J., Poulton R., Williams S. Relationship of serum ferritin with cardiovascular risk factors and inflammation in young men and women. Atherosclerosis. 165:2002;179-184.
20. Facchini F.S., Saylor K.L. Effect of iron depletion on cardiovascular risk factors: studies in carbohydrate-intolerant patients. Ann. N.Y. Acad. Sci. 967:2002;342-351.
21. Sigurdardottir V., Fagerberg B., Hulthe J. Circulating oxidised low-density lipoprotein (LDL) is associated with risk factors of the metabolic syndrome and LDL size in clinically healthy 58-year old men (AIR study). J. Int. Med. 252:2002;440-447.
22. Fagerberg B., Bokemark L., Hulthe J. The metabolic syndrome, smoking, and antibodies to oxidised LDL in 58-year-old clinically healthy men. Nutr. Metab. Cardiovasc. Dis. 11:2001;227-235.
23. Iribarren C., Sempos C.T., Eckfeldt J.H., Folsom A.R. Lack of association between ferritin level and measures of LDL oxidation: the ARIC study. Atherosclerosis risk in communities. Atherosclerosis. 139:1998;189-195.
24. Salonen J.T., Korpela H., Porkkala E., Tuomainen T.-P. Lowering of body iron stores by blood letting and oxidation resistance of serum lipoproteins: a randomised cross-over trial in male smokers. J. Intern. Med. 237:1995;161-168.
25. Gaenzer H., Marschang P., Sturm W., Neumayr G., Vogel W., Patsch J., Weiss G. Association between increased iron stores and impaired endothelial function in patients with hereditary hemochromatosis. J. Am. Coll. Cardiol. 40:2002;2189-2194.