8-Isoprostane increases expression of interleukin-8 in human macrophages through activation of mitogen-activated protein kinases

Cardiovascular Research

Volumn 59, Issue 4, 2003, Pages 945-954

  Scholz, Hanne ^a   Yndestad, Arne ^a   Damås, Jan Kristian ^a   Wæhre, Torgun ^a   Tonstad, Serena ^b   Aukrust, Pål ^a   Halvorsen, Bente ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

Atherosclerosis; Free radicals; Inflammation; Macrophages; Protein kinases

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 8 ISOPROSTANE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; ISOPROSTANE DERIVATIVE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN; PROTEIN 1ALPHA; SYNAPSIN I; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME IMMUNOASSAY; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBONUCLEASE PROTECTION ASSAY;

EID: 0842270943     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(03)00538-8     Document Type: Article

References (45)

1. Libby P. Changing concepts of atherogenesis. J. Intern. Med. 247:2000;349-358.
2. Ross R. Atherosclerosis - an inflammatory disease. New Engl J. Med. 340:1999;115-126.
3. Suarna C., Dean R.T., May J., Stocker R. Human atherosclerotic plaque contains both oxidized lipids and relatively large amounts of alpha-tocopherol and ascorbate. Arterioscler. Thromb. Vasc. Biol. 15:1995;1616-1624.
4. Navab M., Berliner J.A., Watson A.D., et al. The Yin and Yang of oxidation in the development of the fatty streak. A review based on the 1994 George Lyman Duff Memorial Lecture. Arterioscler Thromb Vasc Biol. 16:1996;831-842.
5. Morrow J.D., Awad J.A., Boss H.J., Blair I.A., Roberts L.J. Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids. Proc Natl Acad Sci USA. 89:1992;10721-10725.
6. Morrow J.D., Chen Y., Brame C.J., et al. The isoprostanes: unique prostaglandin-like products of free-radical-initiated lipid peroxidation. Drug Metab Rev. 31:1999;117-139.
7. Patrono C., FitzGerald G.A. Isoprostanes: potential markers of oxidant stress in atherothrombotic disease. Arterioscler Thromb Vasc Biol. 17:1997;2309-2315.
8. Pratico D., Iuliano L., Mauriello A., et al. Localization of distinct F2-isoprostanes in human atherosclerotic lesions. J Clin Invest. 100:1997;2028-2034.
9. Waddington E.I., Puddey I.B., Mori T.A., Croft K.D. Similarity in the distribution of F2-isoprostanes in the lipid subfractions of atherosclerotic plaque and in vitro oxidised low density lipoprotein. Redox Rep. 7:2002;179-184.
10. Pratico D., Tangirala R.K., Rader D.J., Rokach J., FitzGerald G.A. Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice. Nature Med. 4:1998;1189-1192.
11. Simonini A., Moscucci M., Muller D.W., et al. IL-8 is an angiogenic factor in human coronary atherectomy tissue. Circulation. 101:2000;1519-1526.
12. Boisvert W.A., Curtiss L.K., Terkeltaub R.A. Interleukin-8 and its receptor CXCR2 in atherosclerosis. Immunol Res. 21:2000;129-137.
13. Su B., Karin M. Mitogen-activated protein kinase cascades and regulation of gene expression. Curr Opin Immunol. 8:1996;402-411.
14. Jing Q., Xin S.M., Zhang W.B., et al. Lysophosphatidylcholine activates p38 and p42/44 mitogen-activated protein kinases in monocytic THP-1 cells, but only p38 activation is involved in its stimulated chemotaxis. Circ Res. 87:2000;52-59.
15. Fu Y., Luo N., Lopes-Virella M.F. Upregulation of interleukin-8 expression by prostaglandin D2 metabolite 15-deoxy-delta12,14 prostaglandin J2 (15d-PGJ2) in human THP-1 macrophages. Atherosclerosis. 160:2002;11-20.
16. Aukrust P., Berge R.K., Ueland T., et al. Interaction between chemokines and oxidative stress: possible pathogenic role in acute coronary syndromes. J Am Coll Cardiol. 37:2001;485-491.
17. Muller F., Rollag H., Froland S.S. Reduced oxidative burst responses in monocytes and monocyte-derived macrophages from HIV-infected subjects. Clin Exp Immunol. 82:1990;10-15.
18. Yndestad A., Kristian Damas J., Geir Eiken H., et al. Increased gene expression of tumor necrosis factor superfamily ligands in peripheral blood mononuclear cells during chronic heart failure. Cardiovasc Res. 54:2002;175-182.
19. Damas J.K., Gullestad L., Ueland T., et al. CXC-chemokines, a new group of cytokines in congestive heart failure - possible role of platelets and monocytes. Cardiovasc Res. 45:2000;428-436.
20. Cuenda A., Rouse J., Doza Y.N., et al. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364:1995;229-233.
21. Alessi D.R., Cuenda A., Cohen P., Dudley D.T., Saltiel A.R. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem. 270:1995;27489-27494.
22. Fu Y., Luo N., Lopes-Virella M.F. Oxidized LDL induces the expression of ALBP/aP2 mRNA and protein in human THP-1 macrophages. J Lipid Res. 41:2000;2017-2023.
23. Lemay S., Lebedeva T.V., Singh A.K. Inhibition of cytokine gene expression by sodium salicylate in a macrophage cell line through an NF-kappaB-independent mechanism. Clin Diagn Lab Immunol. 6:1999;567-572.
24. Abate A., Schroder H. Protease inhibitors protect macrophages from lipopolysaccharide-induced cytotoxicity: possible role for NF-kappaB. Life Sci. 62:1998;1081-1088.
25. Halvorsen B., Ranheim T., Nenseter M.S., Huggett A.C., Drevon C.A. Effect of a coffee lipid (cafestol) on cholesterol metabolism in human skin fibroblasts. J Lipid Res. 39:1998;901-912.
26. Reape T.J., Groot P.H. Chemokines and atherosclerosis. Atherosclerosis. 147:1999;213-225.
27. Ohki R., Yamamoto K., Mano H., et al. Identification of mechanically induced genes in human monocytic cells by DNA microarrays. J Hypertens. 20:2002;685-691.
28. Halvorsen B., Staff A.C., Henriksen T., Sawamura T., Ranheim T. 8-iso-prostaglandin F(2alpha) increases expression of LOX-1 in JAR cells. Hypertension. 37:2001;1184-1190.
29. Minuz P., Andrioli G., Degan M., et al. The F2-isoprostane 8-epiprostaglandin F2alpha increases platelet adhesion and reduces the antiadhesive and antiaggregatory effects of NO. Arterioscler Thromb Vasc Biol. 18:1998;1248-1256.
30. Leitinger N., Huber J., Rizza C., et al. The isoprostane 8-iso-PGF(2alpha) stimulates endothelial cells to bind monocytes: differences from thromboxane-mediated endothelial activation. FASEB J. 15:2001;1254-1256.
31. Hoffmann E., Dittrich-Breiholz O., Holtmann H., Kracht M. Multiple control of interleukin-8 gene expression. J Leukoc Biol. 72:2002;847-855.
32. Azuma Y., Ohura K. Endomorphins 1 and 2 inhibit IL-10 and IL-12 production and innate immune functions, and potentiate NF-kappaB DNA binding in THP-1 differentiated to macrophage-like cells. Scand J Immunol. 56:2002;260-269.
33. Delanty N., Reilly M.P., Pratico D., et al. 8-epi PGF2 alpha generation during coronary reperfusion. A potential quantitative marker of oxidant stress in vivo. Circulation. 95:1997;2492-2499.
34. Cyrus T., Yao Y., Rokach J., Tang L.X., Pratico D. Vitamin E reduces progression of atherosclerosis in low-density lipoprotein receptor-deficient mice with established vascular lesions. Circulation. 107:2003;521-523.
35. Lim P.S., Chang Y.M., Thien L.M., et al. 8-iso-prostaglandin f(2alpha) as a useful clinical biomarker of oxidative stress in ESRD patients. Blood Purif. 20:2002;537-542.
36. Cyrus T., Tang L.X., Rokach J., FitzGerald G.A., Pratico D. Lipid peroxidation and platelet activation in murine atherosclerosis. Circulation. 104:2001;1940-1945.
37. Minuz P., Gaino S., Zuliani V., et al. Functional role of p38 mitogen activated protein kinase in platelet activation induced by a thromboxane A2 analogue and by 8-iso-prostaglandin F2alpha. Thromb Haemost. 87:2002;888-898.
38. Shin W.S., Szuba A., Rockson S.G. The role of chemokines in human cardiovascular pathology: enhanced biological insights. Atherosclerosis. 160:2002;91-102.
39. Mohler E.R., Franklin M.T., Adam L.P. Intracellular signaling by 8-epi-prostaglandin F2 alpha is mediated by thromboxane A2/prostaglandin endoperoxide receptors in porcine carotid arteries. Biochem Biophys Res Commun. 225:1996;915-923.
40. Lei Z.B., Zhang Z., Jing Q., et al. OxLDL upregulates CXCR2 expression in monocytes via scavenger receptors and activation of p38 mitogen-activated protein kinase. Cardiovasc Res. 53:2002;524-532.
41. Holtmann H., Winzen R., Holland P., et al. Induction of interleukin-8 synthesis integrates effects on transcription and mRNA degradation from at least three different cytokine- or stress-activated signal transduction pathways. Mol Cell Biol. 19:1999;6742-6753.
42. Pearson L L., Castle B.E., Kehry M.R. CD40-mediated signaling in monocytic cells: up-regulation of tumor necrosis factor receptor-associated factor mRNAs and activation of mitogen-activated protein kinase signaling pathways. Int Immunol. 13:2001;273-283.
43. Kunsch C., Rosen C.A. NF-kappa B subunit-specific regulation of the interleukin-8 promoter. Mol Cell Biol. 13:1993;6137-6146.
44. Hipp M S., Urbich C., Mayer P., et al. Proteasome inhibition leads to NF-kappaB-independent IL-8 transactivation in human endothelial cells through induction of AP-1. Eur J Immunol. 32:2002;2208-2217.
45. Zafarullah M., Li W Q., Sylvester J., Ahmad M. Molecular mechanisms of N-acetylcysteine actions. Cell Mol Life Sci. 60:2003;6-20.