-
1
-
-
0026785750
-
Allosteric modifiers of hemoglobin: 2-[4-[[(3,5-disubstituted anilino)carbonyl]methyl]phenoxy]-2-methylpropionic acid derivatives that lower the oxygen affinity of hemoglobin in red cell suspensions, in whole blood, and in vivo in rats
-
Abraham DJ, Wireko FC, Randad RS (1992) Allosteric modifiers of hemoglobin: 2-[4-[[(3,5-disubstituted anilino)carbonyl]methyl]phenoxy]-2- methylpropionic acid derivatives that lower the oxygen affinity of hemoglobin in red cell suspensions, in whole blood, and in vivo in rats. Biochemistry 31:9141
-
(1992)
Biochemistry
, vol.31
, pp. 9141
-
-
Abraham, D.J.1
Wireko, F.C.2
Randad, R.S.3
-
2
-
-
0034875068
-
Enhanced tumor oxygenation and radiation response by the allosteric effector of hemoglobin, RSR13
-
Amorino GP, Lee H, Holburn GE, Pashcal CB, Hercules SK, Shyr Y, Choy H (2001) Enhanced tumor oxygenation and radiation response by the allosteric effector of hemoglobin, RSR13. Radiat Res 156:294
-
(2001)
Radiat Res
, vol.156
, pp. 294
-
-
Amorino, G.P.1
Lee, H.2
Holburn, G.E.3
Pashcal, C.B.4
Hercules, S.K.5
Shyr, Y.6
Choy, H.7
-
3
-
-
0032910812
-
Reducing hemoglobin oxygen affinity does not increase hydroxyl radicals after acute subdural hematoma in the rat
-
Doppenberg EM, Rice MR, Alessandri B, Qian Y, Di X, Bullock R (1999) Reducing hemoglobin oxygen affinity does not increase hydroxyl radicals after acute subdural hematoma in the rat. J Neurotrauma 16:123
-
(1999)
J Neurotrauma
, vol.16
, pp. 123
-
-
Doppenberg, E.M.1
Rice, M.R.2
Alessandri, B.3
Qian, Y.4
Di, X.5
Bullock, R.6
-
4
-
-
0018627373
-
Radiosensitization of hypoxic tumor cells by cis- and trans-dichloroammineplatinum(II)
-
Douple EB, Richmond RC (1979) Radiosensitization of hypoxic tumor cells by cis-and trans-dichloroammineplatinum(II). Int J Radiat Oncol Biol Phys 5:1369
-
(1979)
Int J Radiat Oncol Biol Phys
, vol.5
, pp. 1369
-
-
Douple, E.B.1
Richmond, R.C.2
-
5
-
-
0027222563
-
Effects of cisplatin on the induction of apoptosis in proliferating hepatoma cells and nonproliferating immature thymocytes
-
Evans D, Dice C (1993) Effects of cisplatin on the induction of apoptosis in proliferating hepatoma cells and nonproliferating immature thymocytes. Cancer Res 53:2133
-
(1993)
Cancer Res
, vol.53
, pp. 2133
-
-
Evans, D.1
Dice, C.2
-
6
-
-
0024207211
-
Effect of cancer chemotherapy on the hypoxic fraction of a solid tumor measured using a local tumor control assay
-
Grau C, Overgaard J (1988) Effect of cancer chemotherapy on the hypoxic fraction of a solid tumor measured using a local tumor control assay. Radiother Oncol 13:301
-
(1988)
Radiother Oncol
, vol.13
, pp. 301
-
-
Grau, C.1
Overgaard, J.2
-
7
-
-
0005855687
-
RSR13, an allosteric effector of hemoglobin, and carbogen radiosensitize FSAII and SCCVII tumors in C3H mice
-
Khandelwal SR, Kavanagh BD, Lin PS, Truong QT, Lu J, Abraham DJ, Schmidt-Ullrich RK (1998) RSR13, an allosteric effector of hemoglobin, and carbogen radiosensitize FSAII and SCCVII tumors in C3H mice. Br J Cancer 79:814
-
(1998)
Br J Cancer
, vol.79
, pp. 814
-
-
Khandelwal, S.R.1
Kavanagh, B.D.2
Lin, P.S.3
Truong, Q.T.4
Lu, J.5
Abraham, D.J.6
Schmidt-Ullrich, R.K.7
-
8
-
-
0032796232
-
Phase I trial to determine the safety, pharmacodynamics, and pharmacokinetics of RSR13, a novel radioenhancer, in newly diagnosed glioblastoma multiforme
-
Kleinberg L, Grossman SA, Piantadosi S, Pearlman J, Engelhard H, Lesser G, Ruffer J, Gerber M (1999) Phase I trial to determine the safety, pharmacodynamics, and pharmacokinetics of RSR13, a novel radioenhancer, in newly diagnosed glioblastoma multiforme. J Clin Oncol 17:2593
-
(1999)
J Clin Oncol
, vol.17
, pp. 2593
-
-
Kleinberg, L.1
Grossman, S.A.2
Piantadosi, S.3
Pearlman, J.4
Engelhard, H.5
Lesser, G.6
Ruffer, J.7
Gerber, M.8
-
9
-
-
0024336128
-
Inactivation of hypoxic cells by cisplatin and radiation at clinically relevant doses
-
Korbelik M, Skov KA (1989) Inactivation of hypoxic cells by cisplatin and radiation at clinically relevant doses. Radiat Res 119:145
-
(1989)
Radiat Res
, vol.119
, pp. 145
-
-
Korbelik, M.1
Skov, K.A.2
-
10
-
-
0023921914
-
Oxygen- and temperature-dependent cytotoxic and radiosensitizing effects of cis-dichlorodiammineplatinum(II) on human NHIK 3025 cells in vitro
-
Melvik JE, Pettersen EO (1988) Oxygen-and temperature-dependent cytotoxic and radiosensitizing effects of cis-dichlorodiammineplatinum(II) on human NHIK 3025 cells in vitro. Radiat Res 114:489
-
(1988)
Radiat Res
, vol.114
, pp. 489
-
-
Melvik, J.E.1
Pettersen, E.O.2
-
11
-
-
0021276479
-
Hypoxic fractions of solid tumors: Experimental techniques, methods of analysis, and a survey of existing data
-
Moulder JE, Rockwell S (1984) Hypoxic fractions of solid tumors: experimental techniques, methods of analysis, and a survey of existing data. Int J Radiat Oncol Biol Phys 10:695
-
(1984)
Int J Radiat Oncol Biol Phys
, vol.10
, pp. 695
-
-
Moulder, J.E.1
Rockwell, S.2
-
12
-
-
0025975893
-
Allosteric modifiers of hemoglobin 1: Design, synthesis, testing, and structure-allosteric activity relationship of novel hemoglobin affinity decreasing agents
-
Randad RS, Mahran MA, Mehanna AS (1991) Allosteric modifiers of hemoglobin 1: design, synthesis, testing, and structure-allosteric activity relationship of novel hemoglobin affinity decreasing agents. J Med Chem 4:752
-
(1991)
J Med Chem
, vol.4
, pp. 752
-
-
Randad, R.S.1
Mahran, M.A.2
Mehanna, A.S.3
-
14
-
-
0017603563
-
In vivo-in vitro tumor systems: New models for studying the response of tumors to therapy
-
Rockwell S (1977) In vivo-in vitro tumor systems: new models for studying the response of tumors to therapy. Lab Anim Sci 27:831
-
(1977)
Lab Anim Sci
, vol.27
, pp. 831
-
-
Rockwell, S.1
-
15
-
-
0031737678
-
RSR13, a synthetic allosteric modifier of hemoglobin, as an adjunct to radiotherapy: Preliminary studies with EMT6 cells and tumors and normal tissues in mice
-
Rockwell S, Kelley M (1998) RSR13, a synthetic allosteric modifier of hemoglobin, as an adjunct to radiotherapy: preliminary studies with EMT6 cells and tumors and normal tissues in mice. Radiat Oncol Investig 6:199
-
(1998)
Radiat Oncol Investig
, vol.6
, pp. 199
-
-
Rockwell, S.1
Kelley, M.2
-
16
-
-
0022457633
-
Reactions of tumors and normal tissues in mice to irradiation in the presence and absence of a perfluorochemical emulsion
-
Rockwell S, Mate TP, Irvin CG, Nierenburg M (1986) Reactions of tumors and normal tissues in mice to irradiation in the presence and absence of a perfluorochemical emulsion. Int J Radiat Oncol Biol Phys 12:1315
-
(1986)
Int J Radiat Oncol Biol Phys
, vol.12
, pp. 1315
-
-
Rockwell, S.1
Mate, T.P.2
Irvin, C.G.3
Nierenburg, M.4
-
17
-
-
0026770941
-
Effects of the perfluorochemical emulsion FMIQ on the radiation response of EMT6 tumors
-
Rockwell S, Kelly M, Irvin CG (1992) Effects of the perfluorochemical emulsion FMIQ on the radiation response of EMT6 tumors. Int J Radiat Biol 6:833
-
(1992)
Int J Radiat Biol
, vol.6
, pp. 833
-
-
Rockwell, S.1
Kelly, M.2
Irvin, C.G.3
-
18
-
-
0035055934
-
High-resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector
-
Safo MK, Moure CM, Burnett JC, Joshi GS, Abraham DJ (2001) High-resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector. Protein Sci 10:951
-
(2001)
Protein Sci
, vol.10
, pp. 951
-
-
Safo, M.K.1
Moure, C.M.2
Burnett, J.C.3
Joshi, G.S.4
Abraham, D.J.5
-
20
-
-
0018836776
-
Combination studies with misonidazole and a cis-platinum complex: Cytotoxicity and radiosensitization in vitro
-
Stratford IJ, Williamson C, Adams GE (1980) Combination studies with misonidazole and a cis-platinum complex: cytotoxicity and radiosensitization in vitro. Br J Cancer 41:517
-
(1980)
Br J Cancer
, vol.41
, pp. 517
-
-
Stratford, I.J.1
Williamson, C.2
Adams, G.E.3
-
21
-
-
0027407414
-
Lack of differential radiosensitization of hypoxic cells in a mouse tumor at low radiation doses per fraction by cisplatin
-
Sun JR, Brown JM (1993) Lack of differential radiosensitization of hypoxic cells in a mouse tumor at low radiation doses per fraction by cisplatin. Radiat Res 133:252
-
(1993)
Radiat Res
, vol.133
, pp. 252
-
-
Sun, J.R.1
Brown, J.M.2
-
22
-
-
0019349297
-
Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells
-
Teicher BA, Lazo JS, Sartorelli AC (1981) Classification of antineoplastic agents by their selective toxicities toward oxygenated and hypoxic tumor cells. Cancer Res 41:73
-
(1981)
Cancer Res
, vol.41
, pp. 73
-
-
Teicher, B.A.1
Lazo, J.S.2
Sartorelli, A.C.3
-
23
-
-
0035120517
-
Allosteric modification of oxygen delivery by hemoglobin: Effects of RSR13 on p50 in anesthetized patients
-
Wahr JA, Gerber MJ, Venitz J, Baliga N (2001) Allosteric modification of oxygen delivery by hemoglobin: effects of RSR13 on p50 in anesthetized patients. Anesth Analg 92:615
-
(2001)
Anesth Analg
, vol.92
, pp. 615
-
-
Wahr, J.A.1
Gerber, M.J.2
Venitz, J.3
Baliga, N.4
-
24
-
-
0026080846
-
Allosteric modifiers of hemoglobin 2: Crystallographically determined binding sites and hydrophobic binding/interaction analysis of novel hemoglobin oxygen effectors
-
Wireko FC, Kellogg GE, Abraham DJ (1991) Allosteric modifiers of hemoglobin 2: crystallographically determined binding sites and hydrophobic binding/interaction analysis of novel hemoglobin oxygen effectors. J Med Chem 34:758
-
(1991)
J Med Chem
, vol.34
, pp. 758
-
-
Wireko, F.C.1
Kellogg, G.E.2
Abraham, D.J.3
|