Lead-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma (HepG2) cells

Molecular and Cellular Biochemistry

Volumn 255, Issue 1-2, 2004, Pages 161-170

  Tchounwou, Paul B ^a   Yedjou, Clement G ^a   Foxx, Dominique N ^a   Ishaque, Ali B ^a   Shen, Elaine ^b  

^a JACKSON STATE UNIVERSITY   (United States)

^b Xenometrix Inc USA   (United States)

Author keywords

Cytotoxicity; Gene expression; Human liver carcinoma cells; Lead

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CHLORAMPHENICOL ACETYLTRANSFERASE; CYTOCHROME P450 1A1; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LEAD; LEAD NITRATE; METALLOTHIONEIN; PROTEIN C FOS; PROTEIN P53;

BIOTRANSFORMATION; CELL DAMAGE; CELL PROLIFERATION; CELL STRAIN HEPG2; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; EXPOSURE; GENE FUSION; HUMAN; HUMAN CELL; LD 50; LIVER CARCINOMA; MAMMAL; OXIDATIVE STRESS; PROMOTER REGION; REVIEW; STATISTICAL SIGNIFICANCE; TOXICITY TESTING; TRANSCRIPTION INITIATION;

ARTIFICIAL GENE FUSION; CELL DIVISION; CHLORAMPHENICOL O-ACETYLTRANSFERASE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEAD; LIVER NEOPLASMS; NITRATES; PROMOTER REGIONS (GENETICS); RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED;

FELIS CATUS; MAMMALIA;

EID: 0742271931     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:MCBI.0000007272.46923.12     Document Type: Review

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