Effect of lead and arsenic on murine macrophage response

Drug and Chemical Toxicology

Volumn 25, Issue 4, 2002, Pages 459-472

  Sengupta, Mahuya ^a   Bishayi, Biswadev ^a  

^a UNIVERSITY OF CALCUTTA   (India)

Author keywords

Immunomodulation; Immunosuppression; Lead and arsenic intoxication; Macrophage functions

Indexed keywords

ALKALINE PHOSPHATASE; ARSENIC; ARSENITE SODIUM; DNA FRAGMENT; LEAD; NITRIC OXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; CELL ADHESION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRUCTURE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; IMMUNE RESPONSE; IMMUNOMODULATION; MACROPHAGE FUNCTION; MALE; MOUSE; NONHUMAN; PHAGOCYTOSIS;

ALKALINE PHOSPHATASE; ANIMALS; APOPTOSIS; ARSENITES; CELL ADHESION; DNA FRAGMENTATION; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; NITRIC OXIDE; ORGANOMETALLIC COMPOUNDS; PHAGOCYTOSIS; SODIUM COMPOUNDS; SPLEEN;

ANIMALIA; MURINAE; RODENTIA;

EID: 0036384272     PISSN: 01480545     EISSN: None     Source Type: Journal    
DOI: 10.1081/DCT-120014796     Document Type: Conference Paper

References (19)

1. Waalkes, M.P. In Metal Toxicology; Goyer, R.A., Klassen, C.D., Waalkes, M.P., Eds.; Acadmeic Press: New York, 1995; 54-56.
2. Lawrence, D.A. In Vivo and In Vitro Effects of Lead on Humoral and Cell Mediated Immunity. Infect Immun. 1981, 31, 136-143.
3. Laschi, A.; Eyrand, A.; Morisset, D.; Sanou, A.; Tachon, P.; Veysseyre, C.; Descotes, J. Influence of Heavy Metals on the Resistance of Mice Toward Infection. Immunopharmacol. Immunotoxicol. 1987, 9, 235-241.
4. Robbiano, L.; Carrovini, R.; Puglia, C.P.; Corbu, C.; Brambilla, G. Correlation Between Induction of DNA Fragmentation and Micronuclei Formation in Kidney Cells from Rats and Human and Their Specific Carcinogenic Activity. Toxicol. Appl. Pharmacol. 1999, 166, 133-159.
5. Kyle, R.A. Inorganic Arsenic Intoxication. In Laboratory Diagnosis of Disease Caused by Toxic Agents; Sunderman, F.W., Sunderman, Jr. F.W., Eds.; 1970; pp. 367-370.
6. 38 Dependent Pathway. J. Biol. Chem. 1998, 273, 1917-1922.
7. Luster, M.I.; Blank, J.A. Molecular and Cellular Basis of Chemically Induced Immunotoxicity. Ann. Rev. Pharmacol. Toxicol. 1987, 27, 23-49.
8. Bishayi, B.; Lalitha, R.V.; Ghosh, S. Lead Induced Modulation of Splenic Macrophage Responses on Humoral and Cell Mediated Immunity. Acta Microbiologica. Et. Immunologica. Hungarica 2002, 49: (in press).
9. Bishayi, B. Sodium Arsenite Induced Alteration in Functional Activity of Murine Peritoneal Macrophages. Ind. J. Pharmacol. 2000, 32, 192-197.
10. Sikorsi, E.E.; Burns, L.A.; Stern, M.L.; Luster, M.I.; Munson, A.E. Splenic Cell Targets in Gallium Arsenide Induced Suppression of Primary Antibody Response. Toxicol. Appl. Pharmacol. 1991, 110, 179-192.
11. Lin, T.H.; Roseles, C.; Mordal, K.L.; Bolen, J.B.; Haskill, S.; Juliano, R.L. Integrin Mediated Tyrosine Phosphorylation and Message Induction in Monocytic Cells. J. Biol. Chem. 1995, 270, 16189-16202.
12. Qu, J.; Condliffe, M.A.; Lawson, M.; Plevin, R.J.; Chlivers, E. Lack of Effect of Recombinant Platelet Derived Growth Factor on Human Neutrophil Function. J. Immunol. 1997, 159, 2952-2959.
13. Massman, T. Rapid Colorimetric Assay for Cellular Growth and Survival. J. Immunol. Methods 1983, 65, 55-63.
14. Tietz, N.W. Fundamental of Clinical Chemistry; W.B. Saunders and Company: Philadelphia, PA, 1976; 602.
15. Czuprynski, C.J.; Henson, P.M.; Campbell, P.A. Killing of Listeria monocytogenes by Inflammatory Neutrophils and Mononuclear Phagocytes from Immune and Non Immune Mice. J. Leukocyte Biol. 1984, 35, 193-208.
16. Sasaki, S.; Miura, T.; Nishikawa, S.; Yamada, K.; Hirasue, M.; Nakane, A. Protective Role of Nitric Oxide in S. aureus infection in mice. Infect Immun. 1998, 66, 1017-1022.
17. Ochiai, T.; Fukushima, K.; Ochiai, K. Butyric Acid Induced Apoptosis of Murine Thymocytes, Splenic T Cells and Jurkat-T-Cells. Infect Immun. 1997, 35-41.
18. Tian, L.; Lawrence, D.A. Metal Induced Modulation of Nitric Oxide Production In Vitro by Murine Macrophages. Lead, Nickel and Cobalt Utilize Different Mechanisms. Toxicol. Appl. Pharmacol. 1996, 141, 540-547.
19. Singh, J.; Pritchand, D.E.; Carlisle, D.L.; McLean, J.A.; Montaser, A. Internalization of Carcinogenic Lead Chromate Particles by Cultured Normal Human Epithelial Cells: Formation of Intracellular Lead Inclusion Bodies and Induction of Apoptosin. Toxicol. Appl. Pharmacol. 1999, 161, 240-248.