Effect of excipients on the stability and transport of recombinant human epidermal growth factor (rhEGF) across caco-2 cell monolayers

Archives of Pharmacal Research

Volumn 26, Issue 4, 2003, Pages 330-337

  Kim, In Wha ^a   Yoo, Ho Jung ^b   Song, Im Sook ^b   Chung, Youn Bok ^a   Moon, Dong Cheul ^a   Chung, Suk Jae ^b   Shim, Chang Koo ^b  

^a Chungbuk National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Absorption enhancers; Caco 2 cell monolayer; rhEGF; Stabilizing agents

Indexed keywords

CARRIER PROTEIN; EPIDERMAL GROWTH FACTOR; EXCIPIENT; PHARMACEUTICAL VEHICLES AND ADDITIVES; PRESERVATIVE; RECOMBINANT PROTEIN;

ABSORPTION; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL STRAIN CACO 2; DRUG EFFECT; DRUG STABILITY; ENHANCER REGION; HUMAN; IN VITRO STUDY; METABOLISM; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ABSORPTION; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; DRUG STABILITY; ENHANCER ELEMENTS (GENETICS); EPIDERMAL GROWTH FACTOR; EXCIPIENTS; HUMANS; MEMBRANE TRANSPORT PROTEINS; PHARMACEUTIC AIDS; PRESERVATIVES, PHARMACEUTICAL; RECOMBINANT PROTEINS;

EID: 0642373769     PISSN: 02536269     EISSN: 02536269     Source Type: Journal    
DOI: 10.1007/BF02976964     Document Type: Article

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