메뉴 건너뛰기




Volumn 168, Issue 2, 1998, Pages 189-197

Site-specific degradation and transport of recombinant human epidermal growth factor (rhEGF) in the rat gastrointestinal mucosa

Author keywords

Absorption enhancers; Degradation; Enzyme inhibitors; Gastrointestinal mucosa; rhEGF; Transport

Indexed keywords

BESTATIN; DODECYL SULFATE SODIUM; DRUG METABOLITE; ENZYME INHIBITOR; GLYCEROL PALMITOSTEARATE; HEXANOIC ACID; IODINE 125; PENETRATION ENHANCING AGENT; POLYSORBATE 80; RECOMBINANT EPIDERMAL GROWTH FACTOR; SALICYLATE SODIUM;

EID: 0032527029     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(98)00097-0     Document Type: Article
Times cited : (10)

References (23)
  • 4
    • 0022553189 scopus 로고
    • Epidermal growth factor, its receptor, and related proteins
    • Carpenter G., Zendegui J.G. Epidermal growth factor, its receptor, and related proteins. Exp. Cell Res. 164:1986;1-10.
    • (1986) Exp. Cell Res. , vol.164 , pp. 1-10
    • Carpenter, G.1    Zendegui, J.G.2
  • 5
    • 0016754387 scopus 로고
    • Effect of urogastrone on gastrin secretion and plasma gasrtin levels in normal subjects
    • Elder J.B., Ganguli P.C., Gillespie I.E., Gerring E.L., Gregory H. Effect of urogastrone on gastrin secretion and plasma gasrtin levels in normal subjects. Gut. 16:1975;887-893.
    • (1975) Gut , vol.16 , pp. 887-893
    • Elder, J.B.1    Ganguli, P.C.2    Gillespie, I.E.3    Gerring, E.L.4    Gregory, H.5
  • 6
    • 0021806588 scopus 로고
    • Peptides and proteins as drugs
    • Ferraiolo, B.L., Benet, L.Z., 1985. Peptides and proteins as drugs. Pharm. Res. 2, 151-156.
    • (1985) Pharm. Res. , vol.2 , pp. 151-156
    • Ferraiolo, B.L.1    Benet, L.Z.2
  • 8
    • 0023039369 scopus 로고
    • Uptake and transepithelial transport of nerve growth factor in suckling rat ileum
    • Gonella P., Murphy R., Owen L., Bernanke J., Neutra M. Uptake and transepithelial transport of nerve growth factor in suckling rat ileum. J. Cell. Biol. 103:1986;1979-1990.
    • (1986) J. Cell. Biol. , vol.103 , pp. 1979-1990
    • Gonella, P.1    Murphy, R.2    Owen, L.3    Bernanke, J.4    Neutra, M.5
  • 9
    • 0016719486 scopus 로고
    • Isolation and structure of urogastrone and its relationship to EGF
    • Gregory H. Isolation and structure of urogastrone and its relationship to EGF. Nature. 257:1975;325-327.
    • (1975) Nature , vol.257 , pp. 325-327
    • Gregory, H.1
  • 10
    • 0002458463 scopus 로고
    • Urogastrone and epidermal growth factor
    • In: Kastrup, K.W., Nielsen, J.H. (Eds.) Pergamon Press, Oxford, pp.
    • Gregory, H., Bower, J.M., Willshire, I.R., 1978. Urogastrone and epidermal growth factor. In: Kastrup, K.W., Nielsen, J.H. (Eds.), Growth factors. Pergamon Press, Oxford, pp. 75-84.
    • (1978) Growth Factors , pp. 75-84
    • Gregory, H.1    Bower, J.M.2    Willshire, I.R.3
  • 11
    • 0029552071 scopus 로고
    • Development of luteinizing hormone releasing hormone (LHRH) delivery systems for vaginal mucosal route
    • Han K., Park J.S., Chung Y.B., Jeong N.J., Park H.B., Robinson J.R. Development of luteinizing hormone releasing hormone (LHRH) delivery systems for vaginal mucosal route. Arch. Pharm. Res. 18:1995;325-331.
    • (1995) Arch. Pharm. Res. , vol.18 , pp. 325-331
    • Han, K.1    Park, J.S.2    Chung, Y.B.3    Jeong, N.J.4    Park, H.B.5    Robinson, J.R.6
  • 12
    • 0026579497 scopus 로고
    • Aminopeptidase activity in the jejunal and ileal peyer's patches of the albino rabbit
    • Hayakawa E., Lee V.H.L. Aminopeptidase activity in the jejunal and ileal peyer's patches of the albino rabbit. Pharm. Res. 9:1992;535-540.
    • (1992) Pharm. Res. , vol.9 , pp. 535-540
    • Hayakawa, E.1    Lee, V.H.L.2
  • 13
    • 0022917595 scopus 로고
    • Peptides and related drugs: A review of their absorption, metabolism, and excretion
    • Humphrey J.M., Ringros P.S. Peptides and related drugs: a review of their absorption, metabolism, and excretion. Drug Metab. Rev. 17:1986;283-310.
    • (1986) Drug Metab. Rev. , vol.17 , pp. 283-310
    • Humphrey, J.M.1    Ringros, P.S.2
  • 14
    • 0021061146 scopus 로고
    • Epidermal growth factor inhibits cysteamine-induced duodenal ulcers
    • Kirkegaard P., Olsen P.S., Poulsen S.S., Nexo E. Epidermal growth factor inhibits cysteamine-induced duodenal ulcers. Gastroenterology. 85:1983;1277-1283.
    • (1983) Gastroenterology , vol.85 , pp. 1277-1283
    • Kirkegaard, P.1    Olsen, P.S.2    Poulsen, S.S.3    Nexo, E.4
  • 16
    • 0019824248 scopus 로고
    • Role of mucosal prostaglandins and DNA synthesis in gastric cytoprotection by luminal epidermal growth factor
    • Konturek S.J., Brzozowski T., Piastucki I. Role of mucosal prostaglandins and DNA synthesis in gastric cytoprotection by luminal epidermal growth factor. Gut. 22:1981;927-932.
    • (1981) Gut , vol.22 , pp. 927-932
    • Konturek, S.J.1    Brzozowski, T.2    Piastucki, I.3
  • 19
    • 0016188201 scopus 로고
    • Deamidation of glutaminyl residues: Dependence on pH, temperature, and ionic strength
    • Scotchler J.W., Robinson A.B. Deamidation of glutaminyl residues: Dependence on pH, temperature, and ionic strength. Anal. Biochem. 59:1974;319-322.
    • (1974) Anal. Biochem. , vol.59 , pp. 319-322
    • Scotchler, J.W.1    Robinson, A.B.2
  • 21
    • 0028964291 scopus 로고
    • Stabilization of human epidermal growth factor (rEGF) in aqueous formulation
    • Son K., Kwon C. Stabilization of human epidermal growth factor (rEGF) in aqueous formulation. Pharm. Res. 12:1995;451-454.
    • (1995) Pharm. Res. , vol.12 , pp. 451-454
    • Son, K.1    Kwon, C.2
  • 22
    • 0017131813 scopus 로고
    • Inhibition of aminopeptidase B and leucine aminopeptidase by bestatin and its stereoisomer
    • Suda H., Aoyagi T., Takeuchi T., Umezawa H. Inhibition of aminopeptidase B and leucine aminopeptidase by bestatin and its stereoisomer. Arch. Biochem. Biophys. 177:1976;196-200.
    • (1976) Arch. Biochem. Biophys. , vol.177 , pp. 196-200
    • Suda, H.1    Aoyagi, T.2    Takeuchi, T.3    Umezawa, H.4
  • 23
    • 0010452201 scopus 로고
    • Evidence for specific epidermal growth factor (EGF) receptors on fecal, suckling and adult rat intestinal microvillus membranes (MVM)
    • Tompson, J.F., 1986. Evidence for specific epidermal growth factor (EGF) receptors on fecal, suckling and adult rat intestinal microvillus membranes (MVM). Gastroenterology 90, 1664.
    • (1986) Gastroenterology , vol.90 , pp. 1664
    • Tompson, J.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.