Harnessing the power of RNA interference to advance anticancer drug development

Molecular Cancer Therapeutics

Volumn 2, Issue 3, 2003, Pages 217-218

  Mousses, Spyro ^a  

^a TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; RNA; SMALL INTERFERING RNA; TELOMERASE; TELOMERASE RNA;

DRUG DESIGN; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; NEOPLASM; NOTE; RNA INTERFERENCE; TELOMERE;

DNA-BINDING PROTEINS; DRUG DESIGN; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASMS; RNA; RNA INTERFERENCE; RNA, SMALL INTERFERING; TELOMERASE; TELOMERE;

EID: 0642364466     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Note

References (5)

1. Shay, J. W., and Wright, W. E. Telomerase: a target for cancer therapeutics. Cancer Cells (Cold Spring Harbor), 2: 257-265, 2002. (Pubitemid 41043959)
2. Kosciolek, B. A., Kalantidis, K., Tabler, M., and Rowley, P. T. Inhibition of telomerase activity in human cancer cells by RNA interference Mol. Cancer. Ther., 2: 209-216, 2003.
3. Caplen, N. J., Parrish, S., Imani, F., Fire, A., and Morgan, R. A. Specific inhibition of gene expression by small double-stranded RNAs in invertebrates and vertebrate systems. Proc. Natl. Acad. Sci. USA, 98: 9746-9747, 2001.
4. Elbashir, S. M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (Lond.), 411: 494-498, 2001. (Pubitemid 32494397)
5. Caplen, N. J. A new approach to the inhibition of gene expression. Trends Biotechnol., 20: 49-51, 2002. (Pubitemid 34113937)